Aaron James Mccabe

US Patent:

7277754, Oct 2, 2007

Filed:

Dec 24, 2003

Appl. No.:

10/746855

Inventors:

Aaron McCabe - Minneapolis MN, US
David J. Yonce - Fridley MN, US

Assignee:

Cardiac Pacemakers, Inc. - St. Paul MN

International Classification:

A61N 1/36

US Classification:

607 9, 607 32, 600523, 600509, 128923

Abstract:

An implantable cardiac rhythm management device is configured to remove pacing artifacts from recorded electrograms by a subtraction method. A template waveform representing a recorded pace without accompanying cardiac electrical activity is generated. Such a pacing pulse template is then aligned with the instant at which a pace is delivered and subtracted from the recorded electrogram in order to remove the pacing artifact.

US Patent:

7299086, Nov 20, 2007

Filed:

Mar 5, 2004

Appl. No.:

10/795126

Inventors:

Aaron McCabe - Minneapolis MN, US
Avram Scheiner - Vadnais Heights MN, US
Geng Zhang - Newbury Park CA, US
Quan Ni - White Bear Lake MN, US
Douglas R. Daum - Oakdale MN, US
Yi Zhang - Blaine MN, US

Assignee:

Cardiac Pacemakers, Inc. - St. Paul MN

International Classification:

A61B 5/0428
A61N 1/368

US Classification:

600509, 607 9, 607 32, 607 36

Abstract:

An implantable medical device such as an implantable pacemaker or implantable cardioverter/defibrillator includes a programmable sensing circuit providing for sensing of a signal approximating a surface electrocardiogram (ECG) through implanted electrodes. With various electrode configurations, signals approximating various standard surface ECG signals are acquired without the need for attaching electrodes with cables onto the skin. The various electrode configurations include, but are not limited to, various combinations of intracardiac pacing electrodes, portions of the implantable medical device contacting tissue, and electrodes incorporated onto the surface of the implantable medical device.

US Patent:

7457664, Nov 25, 2008

Filed:

May 9, 2005

Appl. No.:

11/125068

Inventors:

Yi Zhang - Blaine MN, US
Yinghong Yu - Shoreview MN, US
Aaron R. McCabe - Minneapolis MN, US
Jiang Ding - Maplewood MN, US
Jeffrey E. Stahmann - Ramsey MN, US
Carlos Alberto Ricci - Apple Valley MN, US
Scott A. Meyer - Rochester MN, US

Assignee:

Cardiac Pacemakers, Inc. - St. Paul MN

International Classification:

A61N 1/365

US Classification:

607 9

Abstract:

Cardiac monitoring and/or stimulation methods and systems that provide one or more of monitoring, diagnosing, defibrillation, and pacing. Cardiac signal separation is employed to detect, monitor, track, and/or trend closed-loop cardiac resynchronization therapy using cardiac activation sequence information. Devices and methods involve sensing a plurality of composite cardiac signals using a plurality of electrodes, the electrodes configured for implantation in a patient. A source separation is performed using the sensed plurality of composite cardiac signals, producing one or more cardiac signal vectors associated with all or a portion of one or more cardiac activation sequences. A cardiac resynchronization therapy is adjusted using one or both of the one or more cardiac signal vectors and the signals associated with the one or more cardiac signal vectors. In further embodiments, the cardiac resynchronization therapy may be initiated, terminated, or one or more parameters of the resynchronization therapy may be altered.

US Patent:

7509170, Mar 24, 2009

Filed:

May 9, 2005

Appl. No.:

11/124972

Inventors:

Yi Zhang - Blaine MN, US
Jiang Ding - Maplewood MN, US
Aaron R. McCabe - Minneapolis MN, US
Scott A. Meyer - Rochester MN, US

Assignee:

Cardiac Pacemakers, Inc. - St. Paul MN

International Classification:

A61N 1/08
A61N 1/37
A61B 5/0452

US Classification:

607 28, 600512

Abstract:

Cardiac monitoring and/or stimulation methods and systems that provide one or more of monitoring, diagnosing, defibrillation, and pacing. Cardiac signal separation is employed for automatic capture verification using cardiac activation sequence information. Devices and methods sense composite cardiac signals using implantable electrodes. A source separation is performed using the composite signals. One or more signal vectors are produced that are associated with all or a portion of one or more cardiac activation sequences based on the source separation. A cardiac response to the pacing pulses is classified using characteristics associated with cardiac signal vectors and the signals associated with the vectors. Further embodiments may involve classifying the cardiac response as capture or non-capture, fusion or intrinsic cardiac activity. The characteristics may include an angle or an angle change of the cardiac signal vectors, such as a predetermined range of angles of the one or more cardiac signal vectors.

US Patent:

7542800, Jun 2, 2009

Filed:

Apr 5, 2005

Appl. No.:

11/099141

Inventors:

Imad Libbus - St. Paul MN, US
Paul A. Haefner - Circle Pines MN, US
Aaron McCabe - Minneapolis MN, US
Yi Zhang - Blaine MN, US

Assignee:

Cardiac Pacemakers, Inc. - St. Paul MN

International Classification:

A61N 1/36

US Classification:

607 9, 607 2

Abstract:

A neural stimulator senses a reference signal indicative of cardiac cycles each including a predetermined type timing reference event using a sensor external to the heart and blood vessels. The delivery of the neural stimulation pulses are synchronized to that timing reference event. Examples of the timing reference event include a predetermined cardiac event such as a P-wave or an R-wave detected from a subcutaneous ECG signal, a predetermined type heart sound detected from an acoustic signal, and a peak detected from a hemodynamic signal related to blood flow or pressure.

US Patent:

7706866, Apr 27, 2010

Filed:

Jun 24, 2004

Appl. No.:

10/876008

Inventors:

Yi Zhang - St. Paul MN, US
Marina Brockway - Shoreview MN, US
Carlos Alberto Ricci - Apple Valley MN, US
Ron Heil - Roseville MN, US
Douglas R. Daum - Oakdale MN, US
Robert J. Sweeney - Woodbury MN, US
Aaron McCabe - Minneapolis MN, US

Assignee:

Cardiac Pacemakers, Inc. - St. Paul MN

International Classification:

A61B 5/04

US Classification:

600512, 600510, 600511, 600513

Abstract:

Cardiac monitoring and/or stimulation methods and systems provide monitoring, defibrillation and/or pacing therapies. A signal processor receives a plurality of composite signals associated with a plurality of sources, separates a signal using a source separation algorithm, and identifies a cardiac signal using a selected vector. The signal processor may iteratively separate signals from the plurality of composite signals until the cardiac signal is identified. The selected vector may be updated if desired or necessary. A method of signal separation involves detecting a plurality of composite signals at a plurality of locations, separating a signal using source separation, and selecting a vector that provides a cardiac signal. The separation may include a principal component analysis and/or an independent component analysis. Vectors may be selected and updated based on changes of position and/or orientation of implanted components and changes in patient parameters such as patient condition, cardiac signal-to-noise ratio, and disease progression.

US Patent:

7751890, Jul 6, 2010

Filed:

Jul 14, 2004

Appl. No.:

10/890810

Inventors:

Aaron McCabe - Minneapolis MN, US
David J. Yonce - Fridley MN, US

Assignee:

Cardiac Pacemakers, Inc. - St. Paul MN

International Classification:

A61N 1/00
A61B 5/04

US Classification:

607 27, 600510

Abstract:

A self-diagnostic system for an implantable cardiac device such as a pacemaker, cardioverter, or resynchronization device which utilizes a subcutaneous ECG channel is described. The subcutaneous ECG channel allows the device to, in real time and independent of the standard pacing and sensing circuitry, verify the presence of pacing spikes, chamber senses, and other device outputs and hence establish and verify device integrity.

US Patent:

7774061, Aug 10, 2010

Filed:

Dec 23, 2005

Appl. No.:

11/318257

Inventors:

Yi Zhang - Blaine MN, US
Aaron McCabe - Minneapolis MN, US
Kevin J. Stalsberg - White Bear Lake MN, US
Kent Lee - Shoreview MN, US
Marina V. Brockway - Shoreview MN, US
Joseph M. Pastore - Woodbury MN, US
Allan C. Shuros - St. Paul MN, US

Assignee:

Cardiac Pacemakers, Inc. - St. Paul MN

International Classification:

A61N 1/37

US Classification:

607 9, 607 17, 607 18

Abstract:

A cardiac device is described with the capability of detecting cardiac ischemia using multiple sensing modalities. The device may be configured to modify its behavior in delivering therapies to treat bradycardia or tachyarrhythmias in response to detection of cardiac ischemia.