Adel Malek - Wellesley MA, US Andrew Copeland - Cambridge MA, US
Assignee:
The Charles Stark Draper Laboratory, Inc. - Cambridge MA Tufts Medical Center, Inc. - Boston MA
International Classification:
G06K 9/80
US Classification:
382128, 382107, 382130, 382154, 382276, 382284
Abstract:
High resolution time sequences of 3D images that show the dynamics of a time varying changes are provided. The 3D time series of images representing an object that include time varying changes may be produced from lower dimensional image time sequences, such as 2D images. The 2D images may be generated using angiography and may include fluid flow information (e. g. , arrival times). The fluid flow information may be provided, for example, by injecting a chemical into the fluid and analyzing its position in the object or body over time. A varying contrast model may be applied to determine the location of the chemical at different points in time which may assist in detecting an ailment.
Adel M. Malek - Lexington MA, US Eric Miller - Newton MA, US Alexandra Lauric - Medford MA, US
International Classification:
G06K 9/00 A61B 5/103
US Classification:
382128, 600587
Abstract:
An approach to automatically detecting, classifying and/or highlighting abnormal structures such as brain aneurysms is based on three-dimensional studies of the brain vessels. The approach is applicable to effectively all currently available modalities of acquisition of the cerebral vessels, including magnetic resonance angiography (MRA), computed tomography angiography (CTA), and conventional catheter-based three-dimensional rotational angiography (3DRA).
Carl Heilman - Wayland MA, US Adel M. Malek - Lexington MA, US
Assignee:
TUFTS MEDICAL CENTER - Boston MA
International Classification:
A61M 1/00
US Classification:
604 8
Abstract:
An implantable shunt device for draining cerebrospinal fluid from a patient's subarachnoid space. The device includes a shunt having opposed first and second ends. A one-way valve is located at the first end of the shunt. A helical tip is disposed at the second end. The helical tip is constructed to penetrate a sinus wall of the patient. Upon implantation, a hollow passageway extends between the helical tip and one-way valve such that fluid can be drained through the helical tip and out through the valve. The endovascular cerebrospinal fluid shunt of the present invention can be placed into a patient percutaneously via a catheter inserted into the venous system of the body through a needle hole, without the need for open surgery and the skin incisions required with current shunt devices. The device also allows for more physiologic drainage of cerebrospinal fluid since the device is shunting cerebrospinal fluid into the same cerebral venous system that occurs naturally in normal people.
An apparatus includes an embolic coil including a mechanically flexible tubular member having a central lumen and a plurality of expandable sheaths spaced along the axial length of the tubular member, each expandable sheath enveloping and corresponding to the plurality of apertures, the expandable sheaths configured to have an initial low profile arrangement and upon introduction of an expansion medium to the central lumen of the tubular member radially expands to a high profile arrangement. Methods for making and using the apparatus are also described.
An intravascular stent is provided for treatment of an aneurysm in a vessel wall of a cranial blood vessel. The stent includes at least one a flow-shaping member including a flow-facing surface that protrudes from an inner surface of the stent and is configured to control at least one of the direction, velocity and secondary flow characteristics of the blood flow within the aneurysm.
Rami Mangoubi - Newton MA, US Mukund Desai - Needham MA, US Adel Malek - Wellesley MA, US Andrew Copeland - Cambridge MA, US
Assignee:
The Charles Stark Draper Laboratory, Inc. - Cambridge MA Tufts Medical Center, Inc. - Medford MA
International Classification:
G06K 9/80
US Classification:
382128, 382107, 382130, 382154, 382276, 382284
Abstract:
High resolution time sequences of 3D images that show the dynamics of a time varying changes are provided. The 3D time series of images representing an object that include time varying changes may be produced from lower dimensional image time sequences, such as 2D images. The 2D images may be generated using angiography and may include fluid flow information (e. g. , arrival times). The fluid flow information may be provided, for example, by injecting a chemical into the fluid and analyzing its position in the object or body over time. A varying contrast model may be applied to determine the location of the chemical at different points in time which may assist in detecting an ailment.
Implantable shunt devices and methods for draining cerebrospinal fluid from a patient's subarachnoid space include a shunt having opposed first and second ends, the second end being constructed to penetrate a wall of a sigmoid, transverse, straight, or sagittal sinus of the patient, a one-way valve, a hollow passageway extending between the second end and the one-way valve such that cerebrospinal fluid can be drained through the second end and out through the valve, and a mechanism coupled to the shunt and configured to anchor the shunt at a desired location proximal to the subarachnoid space.
Directional Stent For Accessing Extravascular Spaces
An extravascular access system includes a tubular stent configured to be deployed in a blood vessel, the stent having a sidewall and a proximal end opening and an internal scaffolding comprising one or more structural members, and an elongate access catheter having a distal end portion configured to access the blood vessel wherein when the stent is deployed in the blood vessel, and the distal end portion of the catheter is inserted into the proximal end opening of the stent, the one or more internal structural members of the stent deflect the distal end portion of the catheter towards a wall of the blood vessel.
Tufts Medical Center Neurosurgery 800 Washington St FL 7, Boston, MA 02111 6176365858 (phone), 6176367587 (fax)
Education:
Medical School Harvard Medical School Graduated: 1994
Procedures:
Lumbar Puncture Craniotomy Spinal Cord Surgery Spinal Surgery
Languages:
English
Description:
Dr. Adel M. Malek graduated from the Harvard Medical School in 1994. He completed Neurosurgery residency training at Brigham & Women's/Children's Hospitals and Neurointerventional Radiology fellowship training at University of California San Francisco. He has been in practice in Boston, MA since 2001 and specializes in cerebrovascular and endovascular neurosurgery. His interests include