Al Y. Lin - Castro Valley CA, US Thomas B. Neff - Atherton CA, US Noelynn A. Oliver - Los Altos CA, US William R. Usinger - Lafayette CA, US Qingjian Wang - Belmont CA, US David A. Yeowell - San Francisco CA, US
Assignee:
FibroGen, Inc. - South San Francisco CA
International Classification:
C12P 21/08 C07K 16/00
US Classification:
5303871, 5303873, 5303881, 53038823
Abstract:
The present invention relates to antibodies that bind to CTGF. The antibodies are particularly directed to regions of CTGF involved in biological activities associated with fibrosis. The invention also relates to methods of using the antibodies to treat disorders associated with CTGF including localized and systemic fibrotic disorders including those of the lung, liver, heart, skin, and kidney.
Patrick D. Fourney - Walnut Creek CA, US Stephen J. Klaus - San Francisco CA, US Al Y. Lin - Castro Valley CA, US Thomas B. Neff - Atherton CA, US Todd W. Seeley - Moraga CA, US
Assignee:
FibroGen, Inc. - San Francisco CA
International Classification:
C12Q 1/37
US Classification:
514 3, 435 23
Abstract:
The present invention provides methods and compounds for regulating fat metabolism and achieving fat homoeostasis in a subject. Methods and compound for regulating body weight, reducing body fat, and inducing weight loss are also provided, as are methods and compounds for treating or preventing obesity and for preventing or treating conditions associated with altered fat metabolism including, e. g. , obesity, diabetes, atherosclerosis, etc.
Antibodies That Bind To A Portion Of The Vwc Domain Of Connective Tissue Growth Factor
Al Y. Lin - Castro Valley CA, US Thomas B. Neff - Atherton CA, US Noelynn A. Oliver - Los Altos CA, US William R. Usinger - Lafayette CA, US Qingjian Wang - Belmont CA, US David A. Yeowell - San Francisco CA, US
The present invention relates to antibodies that bind to a portion of the Von Willebrand's factor (VWC) domain of connective tissue growth factor (CTGF). The antibodies are particularly directed to regions of CTGF involved in biological activities associated with fibrosis. The invention also relates to methods of using the antibodies to treat disorders associated with CTGF including localized and systemic fibrotic disorders including those of the lung, liver, heart, skin, and kidney.
Patrick D. Fourney - Walnut Creek CA, US Stephen J. Klaus - Boston MA, US Al Y. Lin - Castro Valley CA, US Thomas B. Neff - Atherton CA, US Todd W. Seeley - Oakland CA, US
Assignee:
FibroGen, Inc. - San Francisco CA
International Classification:
A61K 31/47
US Classification:
514 11, 514292, 514307, 514312, 514346, 435375
Abstract:
The present invention provides methods and compounds for regulating fat metabolism and achieving fat homeostasis in a subject. Methods and compound for regulating body weight, reducing body fat, and inducing weight loss are also provided, as are methods and compounds for treating or preventing obesity and for preventing or treating conditions associated with altered fat metabolism including, e. g. , obesity, diabetes, atherosclerosis, etc.
Methods Of Increasing Endogenous Erythropoietin (Epo)
Stephen Klaus - San Francisco CA, US Al Lin - Castro Valley CA, US Thomas Neff - Atherton CA, US Qingjian Wang - Davis CA, US Michael Arend - San Mateo CA, US Lee Flippin - Woodside CA, US Alex Melekhov - San Mateo CA, US
International Classification:
A61K038/17
US Classification:
514/012000
Abstract:
The present invention relates to methods for treating erythropoietin-associated conditions by increasing endogenous erythropoietin in vitro and in vivo. Methods for treating, pretreating or preconditioning, or preventing erythropoietin-associated conditions are also included. Compounds for use in these methods are provided, as are methods of identifying such compounds.
Methods Of Increasing Endogenous Erythropoietin (Epo)
Stephen Klaus - San Francisco CA, US Al Lin - Castro Valley CA, US Thomas Neff - Atherton CA, US Qingjian Wang - Belmont CA, US Michael Arend - Foster City CA, US Lee Flippin - Woodside CA, US Alex Melekhov - Irvine CA, US
Assignee:
FibroGen, Inc. - South San Francisco CA
International Classification:
A61K 31/47 A61K 38/04
US Classification:
514019000, 514310000
Abstract:
The present invention relates to methods for treating erythropoietin-associated conditions by increasing endogenous erythropoietin in vitro and in vivo. Methods for treating, pretreating or preconditioning, or preventing erythropoietin-associated conditions are also included. Compounds for use in these methods are provided, as are methods of identifying such compounds.
Methods Of Increasing Endogenous Erythropoietin (Epo)
Stephen Klaus - San Francisco CA, US Al Lin - Castro Valley CA, US Thomas Neff - Atherton CA, US Qingjian Wang - Belmont CA, US Michael Arend - Foster City CA, US Lee Flippin - Woodside CA, US Alex Melekhov - Irvine CA, US
Assignee:
FibroGen, Inc. - South San Francisco CA
International Classification:
A61K 38/04 A61K 31/4745
US Classification:
514019000, 514291000
Abstract:
The present invention relates to methods for treating erythropoietin-associated conditions by increasing endogenous erythropoietin in vitro and in vivo. Methods for treating, pretreating or preconditioning, or preventing erythropoietin-associated conditions are also included. Compounds for use in these methods are provided, as are methods of identifying such compounds.
Methods Of Increasing Endogenous Erythropoietin (Epo)
Stephen Klaus - San Francisco CA, US Al Lin - Castro Valley CA, US Thomas Neff - Atherton CA, US Qingjian Wang - Belmont CA, US Michael Arend - Foster City CA, US Lee Flippin - Woodside CA, US Alex Melekhov - Irvine CA, US
Assignee:
FibroGen, Inc. - South San Francisco CA
International Classification:
A61K 38/04 A61K 31/502
US Classification:
514019000, 514248000
Abstract:
The present invention relates to methods for treating erythropoietin-associated conditions by increasing endogenous erythropoietin in vitro and in vivo. Methods for treating, pretreating or preconditioning, or preventing erythropoietin-associated conditions are also included. Compounds for use in these methods are provided, as are methods of identifying such compounds.
Name / Title
Company / Classification
Phones & Addresses
Al Lin Director Preclin Develop And Pharmacol
Fibrogen, Inc. Pharmaceutical Preparations
409 Illinois St, San Francisco, CA 94158
Al Lin Director Preclin Develop And Pharmacol
FibroGen, Inc. Biotechnology · Mfg Pharmaceutical Preparations · Physical Medicine
409 Illinois St, San Francisco, CA 94158 4159781200, 4159781902, 8007207203
Partners IV - Cranford, NJ since 2002
Assistant Director
Partners Pharmacy - Cranford, NJ 2000 - 2002
Staff
Alpine Medical 1999 - Jan 2000
Pharmacist in Charge
Apria Healthcare 1997 - 1999
Staff Pharmacist
. 1990 - 1994
.
Education:
University of the Sciences in Philadelphia 1989 - 1994
BS, Pharmacy
Skills:
Infusion Pumps Workflow Infusion Health Clinical Research Pharmacy Benefit Home Care Healthcare Pharmacy Automation Healthcare Information Tpns Clinical Healthcare It Oncology Healthcare Information Technology Home Infusion Managed Care Pbm Pharmacy Benefit Management Diabetes Clean Rooms Management Informatics Pharmacy Hospitals
Breadcrumb Point of Sale
Software Engineer
Grant Thornton Llp 2012 - 2013
Advisory Associate
Golden Gate University Sep 1, 2009 - Aug 1, 2012
L1 and L2 Technical Support
Wall Street English Jan 1, 2012 - Jul 1, 2012
Hustler of the English Language
Pwc Jun 2011 - Aug 2011
Risk Assurance Summer Intern
Education:
Open University
Community College
Skills:
Auditing Writing Physics Csu Community Service Comments Art Accounting Renewal D3.Js Units Corporate Finance Jquery C Node.js Ruby Mongodb Rights Enterprise Risk Management Calculus Cost Accounting Undergraduate Community History Students Entry Home Sci Clearance Crafts Lin Sage Act Hum Privacy Law American History React.js Continuing Education Financial Accounting San Francisco Fin Operations Management Families Warehouse Management Microsoft Excel India Admin Organizational Behavior Acad Credit Ext Javascript Int Financial Analysis Ruby on Rails China Assessment Bus Sem Software Engineering Css Coffeescript Image Credit Evaluation Gateway Culture Business Communications Compensation Mysql Print
Intel Corporation 2006 - 2016
Functional and Debug Logic and Physical Design and Automation Owner | Debug Team Lead
Xilinx 2006 - 2016
Ic Design Engineer
Broadcom 2016 - 2016
Arm Server Asic Design Automation Owner
Intel Corporation 2000 - 2006
Cpu Instruction Decode Logic and Physical Design Owner | System Debug Team Lead
San Francisco Bay Area 2000 - 2006
Education:
Stanford University
Bachelors, Electrical Engineering
Stanford University
Masters, Electrical Engineering
Skills:
Microprocessors Soc Circuit Design Debugging Verilog Perl Dft Asic Ic Logic Design Static Timing Analysis Integrated Circuits Rtl Design Physical Design System on A Chip Application Specific Integrated Circuits Python Management Project Planning Simulations Emulation Rtl Verification Processors Automatic Test Pattern Generation Field Programmable Gate Arrays Eda