Alan C Rapraeger from Stoughton, WI, age 74

Name / Title

Company / Classification

Phones & Addresses

Alan C. Rapraeger
President

Driftwood Pointe Estates Homeowners Association
Civic/Social Association

99262 Winchuck Riv Rd, Harbor, OR 97415

Syndecan 1 Ectodomain Inhibits Cancer
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US Patent:

20070054332, Mar 8, 2007
Filed:

Aug 8, 2006
Appl. No.:

11/501209
Inventors:

Alan Rapraeger - Madison WI, US
Yan Ji - Madison WI, US
International Classification:

G01N 33/574
A61K 38/17
A61K 38/10
A61K 38/08
US Classification:

435007230, 514012000, 514013000, 514014000, 514015000, 514016000, 514017000
Abstract:

The present invention provides for the treatment of cancers, e.g., carcinomas, using the ectodomain of syndecan 1, where the ectodomain lacks heparan sulfate residues. In addition, agents that bind the ectodomain of syndecan 1 also are useful as anti-cancer therapeutics.

Peptides Of Syndecan-1 For Inhibiting Angiogenesis
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US Patent:

20080020979, Jan 24, 2008
Filed:

Jun 8, 2007
Appl. No.:

11/760594
Inventors:

Alan Rapraeger - Madison WI, US
DeannaLee Beauvais - Madison WI, US
International Classification:

A61K 38/00
A61P 43/00
C07H 21/04
C07K 14/00
C07K 7/00
US Classification:

514012000, 514013000, 514014000, 514015000, 514016000, 514017000, 530324000, 530326000, 530327000, 530328000, 530329000, 530330000, 530350000
Abstract:

The present invention provides a peptide derived from the extracellular domain of syndecan-1 that inhibits angiogenesis.

Syndecan Peptides And Polypeptides As Inhibitors Of Cancer
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US Patent:

20140011746, Jan 9, 2014
Filed:

Jul 8, 2013
Appl. No.:

13/936854
Inventors:

Alan RAPRAEGER - Madison WI, US
Assignee:

Wisconsin Alumni Research Foundation - Madison WI
International Classification:

C07K 14/47
US Classification:

514 193, 530324, 530350, 536 235, 435375, 514 213, 514 212
Abstract:

The invention provides for peptides from syndecan 1 and methods of use therefor. These peptides can inhibit α4β6 interaction with HER2, thereby preventing tumor cell growth and tissue invasion.

Syndecan Peptides And Polypeptides As Inhibitors Of Cancer
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US Patent:

20140011747, Jan 9, 2014
Filed:

Jul 8, 2013
Appl. No.:

13/936872
Inventors:

Alan RAPRAEGER - Madison WI, US
Assignee:

Wisconsin Alumni Research Foundation - Madison WI
International Classification:

C07K 14/47
US Classification:

514 193, 530324, 530350, 536 235, 4353201, 435375, 514 213, 514 212
Abstract:

The invention provides for peptides from syndecan 4 and methods of use therefor. These peptides can inhibit α6β4 integrin interaction with EGFR, thereby preventing tumor cell growth and tissue invasion.

Peptides Of Syndecan-1 For Inhibition Of Cancer
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US Patent:

20060134122, Jun 22, 2006
Filed:

Nov 30, 2005
Appl. No.:

11/291112
Inventors:

Alan Rapraeger - Madison WI, US
DeannaLee Beauvais - Madison WI, US
International Classification:

A61K 39/395
C07H 21/04
C12P 21/06
C12N 5/06
C07K 16/30
US Classification:

424155100, 435069100, 435320100, 435338000, 530388800, 536023530
Abstract:

The present invention provides a novel peptide from the extracellular domain of syndecan-1 that inhibits migration, metastasis, survival and proliferation of cancer cells.

Syndecan Peptides And Polypeptides And Uses Thereof
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US Patent:

20170087210, Mar 30, 2017
Filed:

Dec 12, 2016
Appl. No.:

15/375523
Inventors:

- Madison WI, US
Alan Rapraeger - Stoughton WI, US
International Classification:

A61K 38/17
Abstract:

The invention provides for peptides from syndecan 4 and methods of use therefor. These peptides can inhibit α6β4 integrin interaction with EGFR, thereby preventing tumor cell growth and tissue invasion, or inhibiting scarring and/or pathologic neovascularization.

Syndecan Peptides And Polypeptides And Uses Thereof
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US Patent:

20170049852, Feb 23, 2017
Filed:

Oct 18, 2016
Appl. No.:

15/296218
Inventors:

- Madison WI, US
Alan Rapraeger - Stoughton WI, US
International Classification:

A61K 38/17
Abstract:

The invention provides for peptides from syndecan 1 and methods of use therefor. These peptides can inhibit α4β6 interaction with HER2, thereby preventing tumor cell growth and tissue invasion. The peptides can further be used to inhibit scarring and/or to inhibit pathologic neovascularization in a subject.

Syndecan Peptides And Polypeptides As Inhibitors Of Cancer
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US Patent:

20150218237, Aug 6, 2015
Filed:

Apr 16, 2015
Appl. No.:

14/688703
Inventors:

- Madison WI, US
Alan RAPRAEGER - Stoughton WI, US
Assignee:

WISCONSIN ALUMNI RESEARCH FOUNDATION - Madison WI
International Classification:

C07K 14/47
A61K 38/17
Abstract:

The invention provides for peptides from syndecan 4 and methods of use therefor. These peptides can inhibit α6β4 integrin interaction with EGFR, thereby preventing tumor cell growth and tissue invasion.

Alan C Rapraeger