Alex H Chen

US Patent:

7629470, Dec 8, 2009

Filed:

Jul 1, 2005

Appl. No.:

11/629005

Inventors:

Kevin R. Campos - Berkeley Heights NJ, US
Artis Klapars - Scotch Plains NJ, US
J. Christopher McWilliams - Hoboken NJ, US
C. Scott Shultz - Maplewood NJ, US
Debra J. Wallace - Scotch Plains NJ, US
Alex M. Chen - Metuchen NJ, US
Lisa F. Frey - Somerset NJ, US
Andrey V. Peresypkin - Cranford NJ, US
Yaling Wang - Westfield NJ, US
Robert M. Wenslow - Cream Ridge NJ, US
Cheng-Yi Chen - Plainsboro NJ, US

Assignee:

Merck & Co., Inc. - Rahway NJ

International Classification:

C07D 213/63

US Classification:

546290

Abstract:

The present invention is directed to a practical process for the preparation of an enamide (II) by palladium catalyzed coupling of a primary amide (IV) with a compound of structural formula (III), as shown below: As well as to crystalline forms of a compound produced by this process, in particular, an anhydrous crystal form, Form B, and crystalline solvates falling into three patterns, Type 1, Type 2, and Type 3, and crystalline intermediate compounds produced in the process. Still further, the present invention relates to the stereoselective reduction of the tetrasubstituted enamide (II) to the corresponding amide (I).

US Patent:

7839513, Nov 23, 2010

Filed:

Aug 3, 2004

Appl. No.:

10/910413

Inventors:

Ojeni P. Sammis - Glendale CA, US
Peter S. Fisher - Pasadena CA, US
Lily A. Ray - Altadena CA, US
Alexandra D. Ruegg - La Crescenta CA, US
Alex C. Chen - Arcadia CA, US
Vazrik Israelian - Glendale CA, US
James R. Low - Rochester NY, US
Richard T. Horn - Claremont CA, US
Mike L Justice - Fredericksburg VA, US

Assignee:

Xerox Corporation - Norwalk CT

International Classification:

G06K 15/00

US Classification:

358 114, 358 21, 358 19, 358 15, 382100

Abstract:

A hybrid document automation system manages a hybrid printing job, such as PostScript (PS) job with a mix of color and monochrome (B/W) sheets containing variable data. The print job may contain any number of sets, each differing in size and ratio of color and B/W sheets. The system includes a color printer, a monochrome printer, a print manager, a splitter for separating color pages from monochrome pages in the print job and automatic jam recovery. A graphical user interface (GUI) may be provided to give a user/operator information on the status of the print job. The system may also include a document integrity system for insuring the correct output of the merged color and monochrome pages.

US Patent:

8067992, Nov 29, 2011

Filed:

Jun 6, 2008

Appl. No.:

12/134323

Inventors:

Alex Jianzhong Chen - Irvine CA, US
Gim Eng Chew - Penang, MY
Tong Tee Tan - Johor, MY
Kok Chin Pan - Penang, MY

Assignee:

Avago Technologies ECBU IP (Singapore) Pte. Ltd. - Singapore

International Classification:

H03K 3/26

US Classification:

331111, 331 66, 331143, 331175, 331176

Abstract:

Disclosed are various embodiments of temperature-compensated relaxation oscillator circuits that may be fabricated using conventional CMOS manufacturing techniques. The relaxation oscillator circuits described herein exhibit superior low temperature coefficient performance characteristics, and do not require the use of expensive off-chip high precision resistors to effect temperature compensation. Positive and negative temperature coefficient resistors arranged in a resistor array offset one another to provide temperature compensation in the relaxation oscillator circuit.

US Patent:

8294518, Oct 23, 2012

Filed:

Sep 3, 2010

Appl. No.:

12/807403

Inventors:

Sherif Galal - Irvine CA, US
Alex Jianzhong Chen - Irvine CA, US
Khaled Abdelfattah - Irvine CA, US
Todd L. Brooks - Laguna Beach CA, US

Assignee:

Broadcom Corporation - Irvine CA

International Classification:

H03F 3/26

US Classification:

330267, 330265

Abstract:

Disclosed is a Class-AB/B amplifier comprising a first output stage including a first plurality of amplification devices and a second output stage including a second plurality of amplification devices. According to one embodiment, the first output stage operates when the Class-AB/B amplifier is in a quiescent state and the second output stage operates when the Class-AB/B amplifier is in an active state. The Class-AB/B amplifier also comprises a level shifting circuit that adjusts a control voltage of the second output stage, where the level shifting circuit is adapted to activate the second output stage when the Class-AB/B amplifier enters the active state. Embodiments of the Class-AB/B amplifier may include a level shifting circuit that implements either a fixed or signal-dependent level shift, and a quiescent control circuit that substantially eliminates any systematic offset arising from the active feedback circuit inside the replica bias circuit.

US Patent:

20070021430, Jan 25, 2007

Filed:

Sep 17, 2004

Appl. No.:

10/570409

Inventors:

Alex Chen - Metuchen NJ, US
Robert Wenslow - Ream Ridge NJ, US

International Classification:

A61K 31/498
C07D 487/04

US Classification:

514249000, 544350000

Abstract:

The present invention relates to a novel crystalline anhydrate polymorph of the dihydrogenphosphate salt of (2R)-4-oxo-4-[3-trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine as well as a process for their preparation, pharmaceutical compositions containing this novel form, and methods of use of the novel form and pharmaceutical compositions for the treatment of diabetes, obesity, and high blood pressure.

US Patent:

20070136787, Jun 14, 2007

Filed:

Dec 13, 2005

Appl. No.:

11/301427

Inventors:

Alex Chen - Arcadia CA, US
Rene Robles - Santa Maria CA, US
George Hartupee - Racho Cucamonga CA, US

International Classification:

H04L 9/32

US Classification:

726003000

Abstract:

A method and system are provided for authorizing access to software printing resources stored within a memory of a network printing system. The method and system receive user identification information and a request for access to at least one software printing resource of the software printing resources. A determination is then made whether the user identification information corresponds to an authorized user. If the user identification information corresponds to an authorized user, access is given to the at least one software printing resource stored within the memory, thereby enabling the performance of a print job using the at least one software printing resource.

US Patent:

20090131465, May 21, 2009

Filed:

Oct 27, 2008

Appl. No.:

12/290062

Inventors:

Alex M. Chen - Edison NJ, US
Jennifer R. Foley - Garwood NJ, US
John Limanto - Rahway NJ, US
Robert M. Wenslow - Cream Ridge NJ, US
Karen C. Thompson - Lansdale PA, US
Andrey V. Peresypkin - Cambridge MA, US

International Classification:

A61K 31/438
C07D 401/06
A61P 3/04
A61P 3/10
A61P 15/10

US Classification:

514278, 546 17

Abstract:

The present invention relates to a process for producing crystalline N-[1-((3R)-1′-{[(3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrolidine-3-yl]carbonyl}-6-chloro-5-methyl-2,3-dihydrospiro[indene-1,4′-piperidine]-3-yl)-1-methylethyl]acetamide, and novel salts, solvates, hydrates and polymorphs thereof.

US Patent:

20100041893, Feb 18, 2010

Filed:

Oct 22, 2009

Appl. No.:

12/603901

Inventors:

KEVIN R. CAMPOS - Berkeley Heights NJ, US
Artis Klapars - Scotch Plains NJ, US
J. Christopher McWilliams - Hoboken NJ, US
C. Scott Shultz - Maplewood NJ, US
Debra J. Wallace - Scotch Plains NJ, US
Alex M. Chen - Metuchen NJ, US
Lisa F. Frey - Somerset NJ, US
Andrey V. Peresypkin - Cranford NJ, US
Yaling Wang - Westfield NJ, US
Robert M. Wenslow - Cream Ridge NJ, US
Cheng-Yi Chen - Plainsboro NJ, US

International Classification:

C07D 211/72
C07C 233/00

US Classification:

546300, 564123

Abstract:

The present invention is directed to a practical process for the preparation of an enamide (II) by palladium catalyzed coupling of a primary amide (IV) with a compound of structural formula (III), as shown below: As well as to crystalline forms of a compound produced by this process, in particular, an anhydrous crystal form, Form B, and crystalline solvates falling into three patterns, Type 1, Type 2, and Type 3, and crystalline intermediate compounds produced in the process. Still further, the present invention relates to the stereoselective reduction of the tetrasubstituted enamide (II) to the corresponding amide (I).