Alex M Freeman

US Patent:

6335291, Jan 1, 2002

Filed:

Nov 24, 1999

Appl. No.:

09/448705

Inventors:

Alex Freeman - Plano TX

Assignee:

Ball Semiconductor, Inc. - Allen TX

International Classification:

H01L 213065

US Classification:

438706, 438710, 438712, 438713

Abstract:

A system and method for performing plasma etch on a spherical shaped device is disclosed. The system includes a processing tube for providing a reactive chamber for the spherical shaped substrate and a plasma jet is located adjacent to the processing tube. The plasma jet includes a pair of electrodes, such as a central cathode and a surrounding anode, for producing a plasma flame directed towards the reactive chamber. The central cathode may, for example, be powered by a radio frequency power source. As a result, the reactive chamber supports non-contact etching of the spherical shaped substrate by the plasma flame.

US Patent:

6423974, Jul 23, 2002

Filed:

May 28, 1999

Appl. No.:

09/321862

Inventors:

Akira Ishikawa - Royce City TX
Nabuo Takeda - Richardson TX
Suzanne I. Ahn - Dallas TX
Steven R. Hays - Dallas TX
Alex Freeman - Plano TX

Assignee:

Ball Semiconductor, Inc. - Allen TX

International Classification:

H05G 164

US Classification:

25037014, 25037001

Abstract:

A solid state X-ray detector ( ) is disclosed which is comprised of a plurality of Spherical ICs ( )-( ) disposed on a substrate (210). The Spherical ICs each have a plurality of detector picture elements (pixels) ( ) disposed on the surface thereof. Each of the pixels ( ) is formed from a layer of hydrogenated amorphous silicon ( ) with a heavy metal layer ( ) of molybdenum (Mo) disposed thereon as the cathode and a metal layer ( ) disposed on the lower surface thereof. The cathode is reverse biased and X-rays impinging thereon will cause a transfer of electron-holes to the lower plate, which are stored on a capacitor ( ). The electrons are accumulated over a predetermined period of time and then sampled and processed for output on a display ( ) in real time or for storage of a digital value in a memory ( ).

US Patent:

6653124, Nov 25, 2003

Filed:

Nov 10, 2000

Appl. No.:

09/710700

Inventors:

Alex R. Freeman - Plano TX

Assignee:

Cytoplex Biosciences Inc. - Dallas TX

International Classification:

C12M 112

US Classification:

4352971, 4352865, 4352885, 4352887, 4353052

Abstract:

An apparatus and method for cell culture in microchambers that are formed on or adjacent to a substrate. The microchambers are connected by one or more fluid conduits, valves and reagent reservoirs, is disclosed.

US Patent:

6969489, Nov 29, 2005

Filed:

Aug 24, 2001

Appl. No.:

09/939087

Inventors:

Alex Reddy Freeman - Plano TX, US

Assignee:

Cytoplex Biosciences - Plano TX

International Classification:

B01L003/02
B01L011/00
B01L003/00
G01N015/06
G01N035/00

US Classification:

422100, 422 50, 422 55, 422 63, 422 681, 422 81, 422 82, 422101, 422102, 422103, 422104, 436 43, 436 52, 436 53

Abstract:

Array based fluid is stored in through holes that extend through a substrate. Combined capillary and hydrophyllic forces are used to retain the fluid and also transfer it to other substrates of similar type. In another embodiment vacuum and pressure forces are used to introduce the fluid and remove the fluid from the known through holes and transfer the remaining fluid to other substrates. In yet another embodiment, electrokinetic forces are used to retain and move the fluids across the substrates via the through holes. The substrates are aligned and the fluids are transferred or mixed based on the above techniques.

US Patent:

7264617, Sep 4, 2007

Filed:

Feb 28, 2001

Appl. No.:

09/796095

Inventors:

Alex R. Freeman - Plano TX, US

International Classification:

A61K 9/22

US Classification:

6048901, 6048911

Abstract:

Flexible microconduits integral at a proximal end to a substrate and adapted for connection to a biological environment at the distal end are provided. Also provided are microsystems with at least one flexible microconduit integral at a proximal end to a substrate and with a distal end that is adapted for connection to a biological environment. The microconduits may be fluid conduits, electrical conduits, or electro-fluidic conduits that transmit both fluids and electrical signals. Methods for fabricating the microconduits and other structures integral with the substrate are also provided.

US Patent:

20030104512, Jun 5, 2003

Filed:

Nov 30, 2001

Appl. No.:

10/013017

Inventors:

Alex Freeman - Plano TX, US

International Classification:

C12Q001/02

US Classification:

435/029000

Abstract:

The present invention relates to a structure comprising a biological membrane and substrate with fluidic network, an array of membranes and an array of fluidic networks in substrate, a high throughput screen, methods for production of the membrane, substrate structure, and a method for interconnected array of substrate structures and a method for attaching membranes to structure, a method to electrically record events from the membranes and a method to screen large compound library using the array. More particularly, it relates to biological cells and artificial cell membranes adhered to the substrate with a high electrical resistivity seal, a method to manufacture array configuration of such substrates, and a method to screen compounds using the membrane receptors such as ion-channels, ion pumps, & receptors.

US Patent:

60499966, Apr 18, 2000

Filed:

Jul 10, 1998

Appl. No.:

9/113766

Inventors:

Alex Freeman - Frisco TX
Ram Ramamurthi - Allen TX

Assignee:

Ball Semiconductor, Inc. - Allen TX

International Classification:

F26B 308

US Classification:

34362

Abstract:

An apparatus and method for separating fluid from a device such as a spherical shaped semiconductor integrated circuit. To this end, one embodiment provides a first area for receiving the device, a reducing area registering with the first area, a first passage centered in the reducing area, and a second passage adjacent the first passage. The pressure inside the first area is greater than the pressure inside the reducing area. Also, the pressure inside the first passage is greater than the pressure inside the second passage. The device moves through the first area and into the reducing area. Once in the reducing area, the device is inclined to enter the first passage while at least part of the fluid is inclined to enter the second passage. As a result, the fluid is thereby separated from the device.

US Patent:

6077388, Jun 20, 2000

Filed:

Jul 8, 1999

Appl. No.:

9/350045

Inventors:

Alex Freeman - Plano TX

Assignee:

Ball Semiconductor, Inc. - Allen TX

International Classification:

H05H 100
C23C 1600

US Classification:

156345

Abstract:

A system and method for performing plasma etch on a spherical shaped device is disclosed. The system includes a processing tube for providing a reactive chamber for the spherical shaped substrate and a plasma jet is located adjacent to the processing tube. The plasma jet includes a pair of electrodes, such as a central cathode and a surrounding anode, for producing a plasma flame directed towards the reactive chamber. The central cathode may, for example, be powered by a radio frequency power source. As a result, the reactive chamber supports non-contact etching of the spherical shaped substrate by the plasma flame.