Alfredo Cruz Torres

US Patent:

20120082989, Apr 5, 2012

Filed:

Apr 9, 2010

Appl. No.:

13/138845

Inventors:

Alfredo G. Torres - Friendswood TX, US

International Classification:

C12Q 1/68
G01N 33/559
C07H 21/04

US Classification:

435 612, 435 615, 536 2433, 204456

Abstract:

Provided are methods for identifying lpf genes in pathogenic serotypes of the Enterobacteriaceae family and for differentiating () O157:H7 strains in an isolate using primer pairs specific to lpf gene variants, particularly IpfA1 and/or lpfA 2 genes and amplicon size of the PCR product to identify prototypic Enterobacteriaceae serotypes or more specifically, to differentiate strains of serotype O157:1-17. Differentiation further requires identifying the isolate's eae gene variant type which in combination with the IpfA1 and/or lpfA2 variant identification provides unique markers. Also provided are the primer pairs and a kit comprising the same.

US Patent:

20120251565, Oct 4, 2012

Filed:

Mar 19, 2012

Appl. No.:

13/424341

Inventors:

Alfredo G. Torres - Friendswood TX, US
D. Mark Estes - League City TX, US

Assignee:

THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM - AUSTIN TX

International Classification:

C07K 14/195
G01N 33/53
A61P 31/04
A61K 39/02
A61P 37/04

US Classification:

4241901, 530350, 435 71

Abstract:

The present invention provides a protein or a fragment or a variant of said protein, wherein the protein, fragment, or variant is capable of producing a protective immune response in an animal, wherein the immune response is protective against infection by species. Also provided is a method of preventing or treating infection in an animal caused by species which comprises administering an effective amount of the pharmaceutical composition of the present invention to the animal infected with species.

US Patent:

20170333543, Nov 23, 2017

Filed:

May 18, 2017

Appl. No.:

15/598787

Inventors:

- Austin TX, US
Alfredo G. Torres - Friendswood TX, US

International Classification:

A61K 39/02
A61K 9/12
C12N 15/74
C12N 1/36
A61K 39/00

Abstract:

Herein we describe construction of a select agent-excluded ΔtonB Δhcp1 (CLH001) vaccine strain and demonstrate its ability to protect against acute respiratory glanders. Particularly, CLH001 is shown to be attenuated, safe, and effective at protecting against lethal challenge. This strain should be useful in vaccines are for use in humans and animals, e.g., equines, in treating or providing immunoprotection against infections elicited by category B, tier 1 pathogens, in particular (Bm) and , the causative agents of human glanders and melioidosis, respectively.

US Patent:

20170189516, Jul 6, 2017

Filed:

Feb 17, 2017

Appl. No.:

15/436044

Inventors:

Alfredo G. Torres - Friendswood TX, US

Assignee:

THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM - Austin TX

International Classification:

A61K 39/108

Abstract:

Certain embodiments are directed to compositions comprising EHEC-specific antigens. In certain aspects EHEC O157:H7-specific antigen(s) are used as components of immunogenic compositions and vaccines.

US Patent:

20150273038, Oct 1, 2015

Filed:

Mar 4, 2015

Appl. No.:

14/638956

Inventors:

Alfredo G. Torres - Friendswood TX, US

Assignee:

The Board of Regents of the University of Texas System - Austin TX

International Classification:

A61K 39/108

Abstract:

Certain embodiments are directed to compositions comprising EHEC-specific antigens. In certain aspects EHEC O157:H7-specific antigen(s) are used as components of immunogenic compositions and vaccines.

Address:

15214 Lucky Star Dr, Houston, TX 77082

VIN:

1N6AD0ER8AC410221

Make:

NISSAN

Model:

FRONTIER

Year:

2010

Address:

9710 Therrell Dr, Houston, TX 77064

VIN:

4T1BE46K27U711563

Make:

TOYOTA

Model:

CAMRY

Year:

2007

Address:

25 Mdw Gln Dr, Brownsville, TX 78521

VIN:

1GCEC14C67Z553149

Make:

CHEVROLET

Model:

SILVERADO 1500

Year:

2007

Address:

10060 Katy Fwy APT 1604, Houston, TX 77055

VIN:

1HGFA16537L049218

Make:

HONDA

Model:

CIVIC

Year:

2007