Alice Elizabeth White

US Patent:

20210290949, Sep 23, 2021

Filed:

Jul 27, 2017

Appl. No.:

16/321214

Inventors:

- Brentford Middlesex, GB
- Boston MA, US
Charles A. LISSANDRELLO - Boston MA, US
Alice E. WHITE - Boston MA, US
Winthrop GILLIS - Boston MA, US
Jun SHEN - Boston MA, US
Timothy OTCHY - Boston MA, US
Christos MICHAS - Boston MA, US

Assignee:

GALVANI BIOELECTRONICS LIMITED - Brentford Middlesex
TRUSTEES OF BOSTON UNIVERSITY - Boston MA

International Classification:

A61N 1/05
B33Y 10/00
B33Y 80/00
B29C 64/124

Abstract:

Implantable nerve cuffs and methods for constructing or manufacturing the same are provided. Also provided is a method for installing a nerve into a nerve passage in the nerve cuff and a system using the nerve cuff. The nerve cuff is configured to retain one or more signal carrying elements such as electrodes proximal to a peripheral nerve in a human or animal subject. The nerve cuff may be constructed using a 3D printing method.

US Patent:

20210115369, Apr 22, 2021

Filed:

Dec 23, 2020

Appl. No.:

17/132482

Inventors:

- Boston MA, US
Anant Chopra - Waltham MA, US
Alice Elizabeth White - Brookline MA, US
Christopher S. Chen - Newton MA, US

International Classification:

C12M 3/06
A61M 5/168
G09B 23/30
C12M 1/26
F16K 99/00
C12N 5/077

Abstract:

A valve includes a body including an inner bore extending between a first port and a second port, a seat, and one or more restrainers and a disk that is moveable between the seat and the one or more restrainers such that a first pressure that is less than 1 pascal and applied in a first direction causes the disk to move from a first position towards a second position to permit fluid communication between the first port and the second port. A metamaterial scaffold including a structure defining a lumen, at least a portion of an outer or non-lumen surface of the structure is coated with a plurality of biological cells, and wherein the structure is composed of a metamaterial.

US Patent:

20200298490, Sep 24, 2020

Filed:

Mar 19, 2020

Appl. No.:

16/824292

Inventors:

- Boston MA, US
Subramanian Sundaram - Brookline MA, US
Christos Michas - Allston MA, US
Alice E. White - Brookline MA, US
David J. Bishop - Brookline MA, US

International Classification:

B29C 64/30
B29C 64/106
B33Y 10/00
B33Y 30/00

Abstract:

A method for fabricating an electrode includes forming a 3D shell having a hollow interior and defining one or more openings, and directing an electrically conductive liquid through at least one of the one or more openings of the 3D shell, such that the 3D shell is at least partially filed with the electrically conductive liquid. The electrically conductive liquid can be caused to solidify within the 3D shell to form a solid electrode, or can remain a liquid to form a liquid electrode. The 3D shell can be formed having the one or more openings using a 3D printing process such as a two-photon writing system. The surface tension of the electrically conductive liquid aids in retaining the electrically conductive liquid within the 3D shell. The electrode can contact a tissue sample through one of the openings in the 3D shell.

US Patent:

20200017813, Jan 16, 2020

Filed:

Jul 10, 2019

Appl. No.:

16/508033

Inventors:

- Boston MA, US
Anant Chopra - Waltham MA, US
Alice Elizabeth White - Brookline MA, US
Christopher S. Chen - Newton MA, US

International Classification:

C12M 3/06
A61M 5/168
G09B 23/30
C12N 5/077
C12M 1/26
F16K 99/00

Abstract:

A valve includes a body including an inner bore extending between a first port and a second port, a seat, and one or more restrainers and a disk that is moveable between the seat and the one or more restrainers such that a first pressure that is less than 1 pascal and applied in a first direction causes the disk to move from a first position towards a second position to permit fluid communication between the first port and the second port. A metamaterial scaffold including a structure defining a lumen, at least a portion of an outer or non-lumen surface of the structure is coated with a plurality of biological cells, and wherein the structure is composed of a metamaterial.