Alicia Lynn Jensen

US Patent:

20090030480, Jan 29, 2009

Filed:

Jun 26, 2008

Appl. No.:

12/215387

Inventors:

Dominique M. Durand - Solon OH, US
David Yuang Tang - Bratenahl OH, US
Alicia L. Jensen - Cleveland OH, US

Assignee:

CASE WESTERN RESERVE UNIVERSITY - Cleveland OH

International Classification:

A61N 1/36

US Classification:

607 45

Abstract:

Apparatus and methods associated with controlling seizure activity with electrical stimulation that either suppress axonal conduction between brain structures and/or that generate a desired response in a targeted neuronal pool are described. One example apparatus includes an implantable stimulating electrode that provides an electrical stimulus to fiber tracts of the hippocampal commissure of the brain of a subject. The stimulus may be a high frequency structure that prevents communication of signals associated with an epileptic episode and/or prevents seizure activity in a target nucleus. The example apparatus may also include a detection logic that detects specific electrical activity in the central nervous system that identifies that an epileptic episode is imminent. The example apparatus includes a pacing system to selectively configure and apply the electrical stimulus to fiber tracts of the hippocampal commissure of the brain.