Alison R Sullivan

US Patent:

20070092452, Apr 26, 2007

Filed:

Apr 21, 2006

Appl. No.:

11/379727

Inventors:

Terrence Scott - Winchester MA, US
Larry Brown - Newton MA, US
Alison Sullivan - Acton MA, US

International Classification:

A61K 38/27
A61K 9/14

US Classification:

424046000, 514012000

Abstract:

Inhalable spherical particles that contain an active agent having unexpectedly good bioavailability when compared to the expected bioavailability are disclosed. Inhalable spherical particles, particles of the agent that contain an amount of a cation such as zinc provide for further improvement in bioavailability.

US Patent:

20050142201, Jun 30, 2005

Filed:

Jul 19, 2004

Appl. No.:

10/894408

Inventors:

Larry Brown - Newton MA, US
Terrence Scott - Winchester MA, US
Alison Sullivan - Acton MA, US

International Classification:

A61K009/14
A61K038/27

US Classification:

424489000, 514012000

Abstract:

The present invention is related to a method for preparing small spherical particles of an active agent by providing a solution in a single liquid phase. The single liquid phase comprises an active agent, a phase separation enhancing agent, and a first solvent. A phase change is induced at a controlled rate in the solution to cause a liquid-solid phase separation of the active agent and to form a solid phase and a liquid phase. The solid phase comprises solid small spherical particles of the active agent. The liquid phase comprises the phase separation enhancing agent and the solvent. The small spherical particles are substantially spherical and having a size from about 0.01 μm to about 200 μm.

US Patent:

20210030928, Feb 4, 2021

Filed:

Oct 8, 2020

Appl. No.:

17/066466

Inventors:

- Merrimack NH, US
Hui TANG - Acton MA, US
Paul MARTAKOS - Pelham NH, US
Theodore KARWOSKI - Moultonborough NH, US
Alison SULLIVAN - Acton MA, US
Greg MELVILLE - Hudson NH, US
Scott E. CORBEIL - Litchfield NH, US

Assignee:

ATRIUM MEDICAL CORPORATION - Merrimack NH

International Classification:

A61L 31/08
A61L 31/16
A61K 31/4353
A61L 31/14

Abstract:

Fatty acid-based, pre-cure-derived biomaterials, methods of making the biomaterials, and methods of using them as drug delivery carriers are described. The fatty acid-derived biomaterials can be utilized alone or in combination with a medical device for the release and local delivery of one or more therapeutic agents. Methods of forming and tailoring the properties of said biomaterials and methods of using said biomaterials for treating injury in a mammal are also provided.