Allison L Collins

US Patent:

20080124378, May 29, 2008

Filed:

Nov 13, 2007

Appl. No.:

11/985262

Inventors:

Mark E. Byrne - Auburn AL, US
Allison Collins - Mobile AL, US
Asa D. Vaughan - Hurtsboro AL, US
Siddarth Venkatesh - Auburn AL, US

International Classification:

A61K 9/00

US Classification:

424429

Abstract:

A drug delivery system is disclosed. The drug delivery system includes a recognitive polymeric hydrogel through which a drug is delivered by contacting biological tissue. The recognitive polymeric hydrogel is formed using a bio-template, which is a drug or is structurally similar to the drug, functionalized monomers, preferably having complexing sites, and cross-linking monomers, which are copolymerized using a suitable initiator. The complexing sites of the recognitive polymeric hydrogel that is formed preferably mimic receptor sites of a target biological tissue, biological recognition, or biological mechanism of action. A system in accordance with an embodiment of the invention is a contact lens for delivering a drug through contact with an eye. In a particular embodiment of the invention, the drug is an anti-microbial, such as an anti-fungal agent for treatment of large animals, such as horses.