Alvin Donald Crews

US Patent:

7022850, Apr 4, 2006

Filed:

May 18, 2004

Appl. No.:

10/848089

Inventors:

Kyoung S. Kim - North Brunswick NJ, US
Songfeng Lu - Raritan NJ, US
Alvin Donald Crews - Voorhees NJ, US

Assignee:

Bristol-Myers Squibb Co. - Princeton NJ

International Classification:

C07D 498/04
C07D 513/04

US Classification:

544255, 544256

Abstract:

The present invention is directed to dihydropyrimidones having formula I or II and methods of using them to induce mitotic arrest, thereby making them useful as anti-cancer agents and other diseases that can be treated by inducing mitotic arrest.

US Patent:

20010020087, Sep 6, 2001

Filed:

Mar 13, 2001

Appl. No.:

09/805760

Inventors:

Rosie Wong - Piscataway NJ, US
Joseph Pont - Klein-Winternheim, DE
Alvin Crews - Voorhees NJ, US

Assignee:

American Cyanamid Company - Madison NJ

International Classification:

G01N033/53
C07K019/00
C07K016/44

US Classification:

530/405000, 435/007100

Abstract:

The present invention provides an imidazolinone hapten having the structural formula Further provided are an antigen and an enzyme conjugate which are prepared from the imidazolinone hapten. The haptens, antigens and enzyme conjugates provided are useful in immunoassays for determining the presence and concentration of an imidazolinone compound in the presence of one or more other imidazolinone compounds.

US Patent:

53917570, Feb 21, 1995

Filed:

May 9, 1994

Appl. No.:

8/243680

Inventors:

Sergio I. Alvarado - Princeton NJ
Alvin D. Crews - Plainsboro NJ
Peter J. Wepplo - Princeton NJ
Robert F. Doehner - East Windsor NJ
Thomas E. Brady - Whitehouse Station NJ
David M. Gange - Princeton NJ
Desiree L. Little - Burlington NJ

Assignee:

American Cyanamid Company - Wayne NJ

International Classification:

C07D23370
C07D23372
C07D26332

US Classification:

548228

Abstract:

There are provided novel benzenesulfonyl carboxamide compounds and novel intermediate benzenesulfonyl-2-imidazolin-5-one compounds, novel intermediates and methods for the preparation of said compounds, and a method for controlling a variety of annual and perennial plant species utilizing novel benzenesulfonyl carboxamide compounds and novel intermediate benzenesulfonyl 2-imidazolin-5-one compounds.

US Patent:

56124813, Mar 18, 1997

Filed:

Jun 2, 1995

Appl. No.:

8/459567

Inventors:

Alvin D. Crews - Voorhees NJ
Philip M. Harrington - Mercer NJ
Gary M. Karp - Princeton Jct. NJ
Mark C. Manfredi - Hamilton NJ
Michael A. Guaciaro - Hightstown NJ

Assignee:

American Cyanamid Company - Parsippany NJ

International Classification:

C07D40310

US Classification:

544222

Abstract:

There is provided a 1-(3-heterocyclylphenyl)-s-triazine-2,4,6-oxo or thiotrione compound having the structural formula I ##STR1## Further provided are a composition and a method comprising that compound for the control of undesirable plant species.

US Patent:

58722530, Feb 16, 1999

Filed:

Jul 17, 1997

Appl. No.:

8/896254

Inventors:

Alvin Donald Crews - Voorhees NJ
Gary Mitchell Karp - Princeton Jct. NJ
Mark Christopher Manfredi - Hamilton NJ
Michael Anthony Guaciaro - Hightstown NJ

Assignee:

American Cyanamid Company - Madison NJ

International Classification:

C07D23960
C07D41710

US Classification:

544222

Abstract:

There is provided a 1-(3-heterocyclylphenyl)-s-triazine-2, 4,6-oxo or thiotrione compound having the structural formula I ##STR1## Further provided are a composition and a method comprising that compound for the control of undesirable plant species.

US Patent:

56797915, Oct 21, 1997

Filed:

Jul 25, 1996

Appl. No.:

8/686288

Inventors:

Alvin Donald Crews - Voorhees NJ
Gary Mitchell Karp - Princeton Junction NJ
Mark Christopher Manfredi - Hamilton NJ
Michael Anthony Guaciaro - Hightstown NJ

Assignee:

American Cyanamid Company - Parsippany NJ

International Classification:

C07D25134

US Classification:

544222

Abstract:

There is provided a 1-(3-heterocyclylphenyl)-s-triazine-2,4,6-oxo or thiotrione compound having the structural formula I ##STR1## Further provided are a composition and a method comprising that compound for the control of undesirable plant species.

US Patent:

54847621, Jan 16, 1996

Filed:

Feb 10, 1995

Appl. No.:

8/386975

Inventors:

Michael E. Condon - Lawrenceville NJ
Alvin D. Crews - Voorhees NJ
Mark C. Manfredi - Hamilton NJ

Assignee:

American Cyanamid Company - Wayne NJ

International Classification:

A01N 43647
C07D40112
C07D24920

US Classification:

504261

Abstract:

There is provided an aryloxy-N-(substituted phenyl)benzotriazole compound having the structural formula I ##STR1## Further provided are a composition and a method comprising that compound for the control of undesirable plant species.

US Patent:

56101201, Mar 11, 1997

Filed:

Jun 2, 1995

Appl. No.:

8/458639

Inventors:

Alvin D. Crews - Voorhees NJ
Philip M. Harrington - Mercer NJ
Gary M. Karp - Mercer NJ
Mark C. Manfredi - Mercer NJ
Michael A. Guaciaro - Hightstown NJ

Assignee:

American Cyanamid Company - Madison NJ

International Classification:

A01N 4382
A01N 4390
A01N 4366
A01N 43707

US Classification:

504191

Abstract:

There is provided a 1-(3-heterocyclylphenyl)-s-triazine-2,4,6-oxo or thiotrione compound having the structural formula I ##STR1## Further provided are a composition and a method comprising that compound for the control of undesirable plant species.