Dr. Howell graduated from the East Carolina University Brody School Medicine in 2006. She works in Mount Olive, NC and specializes in Pediatrics and Critical Care - Pediatric. Dr. Howell is affiliated with Wayne Memorial Hospital.
A method for crosslinking one or more molecules comprises crosslinking the one or more molecules with a photactivatable crosslinker by one-photon or multi-photon excitation, wherein the crosslinker comprises at least two photoactive groups linked by a bridging moiety, and further wherein the point volume of the activation has at least one dimension of less than about 1 micron. The method is of particular utility for water-soluble molecules, particularly biologically active water-soluble molecules.
Substituted Oxetanes, Method Of Making, And Method Of Use Thereof
Oxetane-containing nucleosides, particularly non-reducing psiconucleoside oxetanes are described herein. Therapeutic application of these oxetane compounds toward the treatment of nucleoside analog related disorders such as disorders involving cellular proliferation and infection are also described.
Substituted Oxetanes, Method Of Making, And Method Of Use Thereof
Oxetane-containing nucleosides, particularly non-reducing psiconucleoside oxetanes are described herein. Therapeutic application of these oxetane compounds toward the treatment of nucleoside analog related disorders such as disorders involving cellular proliferation and infection are also described.
Catalytic Oxidation Of Alcohols Using Manganese Oxides
Steven Suib - Storrs CT, US Young Son - Storrs CT, US Amy Howell - Tolland CT, US
International Classification:
C07C049/29 C07C067/40
US Classification:
560/239000, 568/399000, 568/471000
Abstract:
A method of oxidizing an organic alcohol, wherein the organic alcohol is contacted with a stoichiometric excess of oxygen in the presence of an effective catalytic amount of a manganese-containing octahedral molecular sieve or octahedral layer. Primary alcohols are selectively oxidized to aldehydes, and secondary alcohols are selectively oxidized to ketones.
3-O-Sulfo-Galactosylceramide Analogs As Activators Of Type Ii Nkt Cells And Uses Thereof
- Bethesda MD, US - Farmington CT, US Amy R. Howell - Storrs CT, US Masaki Terabe - Potomac MD, US Kaddy Camara - Storrs CT, US Stewart K. Richardson - Storrs CT, US
Assignee:
The United States of America,as represented by the Secretary,Department of Health and Human Services - Bethesda MD University of Connecticut - Farmington CT
Disclosed is a compound of the formula (I) or (II): wherein a f are as described herein. The compounds are useful in the activation of Type II NKT cells and in treating cancer.
Lactone Compounds And Methods Of Making And Using Same
- La Jolla CA, US - Farmington CT, US William H. PARSONS - San Diego CA, US Amy R. HOWELL - Tolland CT, US Kaddy CAMARA - Brighton MA, US Amy ANDERSON - Storrs CT, US
International Classification:
C07D 305/12 A61K 31/337 A61K 31/365
Abstract:
Provided herein are lactone compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as inhibitors of serine hydrolases, such as ABHD16A. Furthermore, the subject compounds and compositions may be useful for the treatment of, for example, PHARC and other neuroinflammatory diseases.
search director and editor at the Institute for Nonprofit News, got married Saturday at the Barn at Bradstreet Farm in Rowley, Mass. Megan Corrigan officiated. Pic Another pic SPOTTED: David and Anne Gergen, Meghan OSullivan, Karim Farishta, Lucy Moore, Amy Howell, Tim Bishop and Kevin Lownds.
Cranberries have been widely studied for preventing urinary tract infections because they contain substances called proanthocyanidins that may prevent bacteria from sticking on the wall of the bladder, says Amy Howell, PhD, of Rutgers Universitys Marucci Center for Blueberry Cranberry Research.