Amy S Howell

US Patent:

6608102, Aug 19, 2003

Filed:

Sep 2, 1998

Appl. No.:

09/145694

Inventors:

Amy B. Howell - Hammonton NJ
Nicholi Vorsa - Atco NJ

Assignee:

Rutgers, the State University of New Jersey - New Brunswick NJ

International Classification:

A61K 31353

US Classification:

514456, 549400, 549415

Abstract:

The present invention is directed to isolation and identification of plant proanthocyanidin extracts and particular proanthocyanidin compounds for prevention and treatment of urinary tract infections caused by P-type. These extracts can be obtained from any proanthocyanidin-containing plants, including plants of the families Ericaceae, Rosaceae, Pinaceae, Vitaceae and the like. Preferably the extracts are from cranberry plants (especially, ) and other plants, particularly fruit and berry plants from the Vaccinium spp. The extracts and compounds are also provided as pharmaceutical compositions, food additives and food compositions, especially beverages, ground meat preparations and cranberry-containing food products. The invention also relates to methods of reducing pathogenicity of P-type in the digestive tracts of cattle and reducing P-type contamination in ground meat as well as methods of detecting P-type bacteria.

US Patent:

6720353, Apr 13, 2004

Filed:

Apr 30, 2003

Appl. No.:

10/428063

Inventors:

Amy B. Howell - Hamilton NJ
Nicholi Vorsa - Atco NJ

Assignee:

Rutgers, The State University of New Jersey - New Brunswick NJ

International Classification:

A61K 31353

US Classification:

514456, 549400, 549415

Abstract:

The present invention is directed to isolation and identification of plant proanthocyanidin extracts and particular proanthocyanidin compounds for prevention and treatment of urinary tract infections caused by P-type. These extracts can be obtained from any proanthocyanidin-containing plants, including plants of the families Ericaceae, Rosaceae, Pinaceae, Vitaceae and the like. Preferably the extracts are from cranberry plants (especially, ) and other plants, particularly fruit and berry plants from the Vaccinium spp. The extracts and compounds are also provided as pharmaceutical compositions, food additives and food compositions, especially beverages, ground meat preparations and cranberry-containing food products. The invention also relates to methods of reducing pathogenicity of P-type in the digestive tracts of cattle and reducing P-type contamination in ground meat as well as methods of detecting P-type bacteria.

US Patent:

20040013710, Jan 22, 2004

Filed:

Jun 18, 2003

Appl. No.:

10/332425

Inventors:

Amy Howell - Hammonton NJ, US

International Classification:

A61K031/7024
A23K001/165
A23K001/17

US Classification:

424/442000, 514/023000, 536/110000

Abstract:

Hydrolyzable tannin extracts from plants are provided which have activity to prevent bacterial adherence to surfaces. Methods for prevention and treatment of urinary tract and kidney infections in animals and humans are provided.

US Patent:

20040156925, Aug 12, 2004

Filed:

Feb 4, 2004

Appl. No.:

10/772566

Inventors:

Amy Howell - Hamilton NJ, US
Nicholi Vorsa - Atco NJ, US

Assignee:

Rutgers, The State University of New Jersey - New Brunswick NJ

International Classification:

A61K035/78

US Classification:

424/732000, 424/766000, 536/008000, 514/027000, 514/456000

Abstract:

The present invention is directed to isolation and identification of plant proanthocyanidin extracts and particular proanthocyanidin compounds for prevention and treatment of urinary tract infections caused by P-type . These extracts can be obtained from any proanthocyanidin-containing plants, including plants of the families Ericaceae, Rosaceae, Pinaceae, Vitaceae and the like. Preferably the extracts are from cranberry plants (especially, ) and other plants, particularly fruit and berry plants from the Vaccinium spp. The extracts and compounds are also provided as pharmaceutical compositions, food additives and food compositions, especially beverages, ground meat preparations and cranberry-containing food products. The invention also relates to methods of reducing pathogenicity of P-type in the digestive tracts of cattle and reducing P-type contamination in ground meat as well as methods of detecting P-type bacteria.