Amy L Sutton

US Patent:

20120094382, Apr 19, 2012

Filed:

Apr 16, 2010

Appl. No.:

13/264587

Inventors:

Hongkun Park - Cambridge MA, US
EunGyeong Yang - Seoul, KR
Alexander K. Shalek - Cambridge MA, US
JinSeok Lee - Seoul, KR
Jacob Robinson - Somerville MA, US
Amy Sutton - Cambridge MA, US
Myung-Han Yoon - Gwangju, KR
Marsela Jorgolli - Arlington MA, US

Assignee:

President and Fellows of Harvard College - Cambridge MA

International Classification:

C12N 5/071
C12N 5/0781
C07H 23/00
C07F 7/02
B32B 3/02
C12N 5/078
C12N 5/0784
B82Y 5/00

US Classification:

4353722, 435375, 536 231, 5361231, 530402, 556429, 556413, 428 85, 977762, 977902

Abstract:

A molecular delivery system including a plurality of nanowires (e.g., Si NWs), each of the nanowires having a surface layer formed of a silicon-containing material and a covalently bound linker (e.g., silane linker) attached to the surface layer and optionally including a substrate to which the nanowires are adhered or a molecule to be delivered attached to the linker. Also disclosed is a method of delivering into a cell an exogenous molecule.

US Patent:

20130260467, Oct 3, 2013

Filed:

Sep 28, 2011

Appl. No.:

13/876066

Inventors:

Hongkun Park - Lexington MA, US
Jacob Robinson - Somerville MA, US
Amy Sutton - Cambridge MA, US
Marsela Jorgolli - Arlington MA, US
Alexander K. Shalek - Cambridge MA, US

Assignee:

President and Fellows of Harvard - Cambridge MA

International Classification:

C12N 13/00

US Classification:

435455, 4351736, 4352831, 4352852

Abstract:

A molecular delivery device including a plurality of nanowires (e.g., Si NWs) coated with an electrically conductive layer. Also disclosed are methods for delivering a molecule by nanowire-mediated electroporation.

US Patent:

20180119172, May 3, 2018

Filed:

Oct 27, 2017

Appl. No.:

15/795654

Inventors:

- Cambridge MA, US
EunGyeong Yang - Seoul, KR
Alexander K. Shalek - Lexington MA, US
JinSeok Lee - Cambridge MA, US
Jacob Robinson - Somerville MA, US
Amy Sutton - Cambridge MA, US
Myung-Han Yoon - Cambridge MA, US
Marsela Jorgolli - Arlington MA, US

International Classification:

C12N 15/89
G01N 33/50
C12Q 1/68
G01N 33/543
C12N 5/00

Abstract:

A molecular delivery system including a plurality of nanowires (e.g., Si NWs), each of the nanowires having a surface layer formed of a silicon-containing material and a covalently bound linker (e.g., silane linker) attached to the surface layer and optionally including a substrate to which the nanowires are adhered or a molecule to be delivered attached to the linker. Also disclosed is a method of delivering into a cell an exogenous molecule.

US Patent:

20160281110, Sep 29, 2016

Filed:

Feb 23, 2016

Appl. No.:

15/051418

Inventors:

- Cambridge MA, US
EunGyeong Yang - Seoul, KR
Alexander K. Shalek - Cambridge MA, US
JinSeok Lee - Cambridge MA, US
Jacob Robinson - Somerville MA, US
Amy Sutton - Cambridge MA, US
Myung-Han Yoon - Cambridge MA, US
Marsela Jorgolli - Arlington MA, US

International Classification:

C12N 15/89
G01N 33/50
C12Q 1/68
C12N 5/00

Abstract:

A molecular delivery system including a plurality of nanowires (e.g., Si NWs), each of the nanowires having a surface layer formed of a silicon-containing material and a covalently bound linker (e.g., silane linker) attached to the surface layer and optionally including a substrate to which the nanowires are adhered or a molecule to be delivered attached to the linker. Also disclosed is a method of delivering into a cell an exogenous molecule.