Amy E Wood

US Patent:

20210054327, Feb 25, 2021

Filed:

Mar 13, 2019

Appl. No.:

16/964646

Inventors:

- Burlington MA, US
Amy Wood - Concord MA, US
David Kraus - Amherst NH, US

International Classification:

C12M 1/00
C12M 3/00
C12M 1/06
C12M 1/34

Abstract:

A collapsible container for a fluid that includes a flexible material, defining an internal working volume; at least one collapsible baffle adhered within the working volume of said collapsible container, the at least one baffle having one or more channels for delivering one or more fluids into the working volume via at least one hole in said one or more channels, one or more channels in said container for exiting or venting fluids from the working volume, and an impeller assembly disposed at least partially within said working volume of said container.

US Patent:

20160040113, Feb 11, 2016

Filed:

Mar 17, 2014

Appl. No.:

14/782487

Inventors:

- Billerica MA, US
Anne Hansen - Billerica MA, US
James McSweeney - Billerica MA, US
David Kraus - Billerica MA, US
Jeffrey Pearsons - Billerica MA, US
Amy Wood - Billerica MA, US

Assignee:

EMD Millipore Corporation - Billerica MA

International Classification:

C12M 1/00
C12M 1/12

Abstract:

A container, such as a disposable or single use bioreactor, optionally having one or more inlets and one or more outlets and a mixer associated with the container to cause mixing, dispersing, homogenizing and/or circulation of one or more ingredients contained or added to the container. The container includes a flexible baffle shaped and positioned within the container to improve mixing, particularly to improve low shear mixing. The baffle is positioned within the container so as to disrupt the vortex formed by the mixer, or prevent formation of a vortex. The baffle is shaped with both horizontal and vertical elements to enhance disruption of the vortex across the entire vessel height and provide homogeneous mixing throughout all operating volumes. In certain embodiments, the baffle is X-shaped.