Director, Virology & Molecular Biology at Batavia Bioservices
Location:
Greater Boston Area
Industry:
Biotechnology
Work:
Novartis Vaccines and Diagnostics - Cambridge, MA since Mar 2013
Research Investigator I
Novartis Vaccines and Diagnostics since Sep 2010
Associate Project Leader
Novartis Vaccines and Diagnostics - Cambridge, MA Sep 2011 - Feb 2013
Investigator II
Novartis Vaccines and Diagnostics - Cambridge, MA Mar 2009 - Sep 2011
Investigator I
Princeton University - Princeton, NJ Sep 2002 - Jan 2009
Postdoc
Education:
University of Maryland College Park 1997 - 2002
Ph.D., Biochemistry
Chalmers University of Technology 1992 - 1996
M.Sc., Chemical Engineering
Skills:
Vaccines Virology DNA Agarose Gel Electrophoresis Bacterial Transformation Subcloning Site-directed Mutagenesis Primer Design DNA extraction RNA isolation Northern Blotting Transfection Vector NTI recombinant DNA technology Viruses Molecular Biology Biotechnology Tissue Culture Gene Expression cDNA Electroporation Gel Extraction Nanodrop Restriction Mapping Miniprep Vector Cloning
This disclosure provides platforms for delivery of herpes virus proteins to cells, particularly proteins that form complexes in vivo. In some embodiments these proteins and the complexes they form elicit potent neutralizing antibodies. Thus, presentation of herpes virus proteins using the disclosed platforms permits the generation of broad and potent immune responses useful for vaccine development.
- Rixensart, BE Anders LILJA - Somerville MA, US Rebecca LOOMIS - Philadelphia PA, US Peter W. MASON - Somerville MA, US
Assignee:
GLAXOSMITHKLINE BIOLOGICALS SA - Rixensart
International Classification:
C07K 14/005 C12N 15/86 A61K 39/12
Abstract:
This disclosure provides platforms for delivery of herpes virus proteins to cells, particularly proteins that form complexes in vivo. In some embodiments these proteins and the complexes they form elicit potent neutralizing antibodies. Thus, presentation of herpes virus proteins using the disclosed platforms permits the generation of broad and potent immune responses useful for vaccine development.
- Rixensart, BE Anders Lilja - Somerville MA, US Rebecca Loomis - Philadelphia, PA Peter Mason - Somerville MA, US
Assignee:
GLAXOSMITHKLINE BIOLOGICALS, SA - Rixensart
International Classification:
C07K 14/005 C12N 15/86 A61K 39/12
Abstract:
This disclosure provides platforms for delivery of herpes virus proteins to cells, particularly proteins that form complexes in vivo. In some embodiments these proteins and the complexes they form elicit potent neutralizing antibodies. Thus, presentation of herpes virus proteins using the disclosed platforms permits the generation of broad and potent immune responses useful for vaccine development.
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