Andrea M Rourke

US Patent:

20010035184, Nov 1, 2001

Filed:

Dec 6, 2000

Appl. No.:

09/731316

Inventors:

Carlos Schuler - Cupertino CA, US
Steve Paboojian - Menlo Park CA, US
Andrew Clark - Half Moon Bay CA, US
Andrea Rourke - San Mateo CA, US
Joanne Curley - San Mateo CA, US
Don Minami - Monte Sereno CA, US
Derrick Tuttle - San Jose CA, US

International Classification:

A61M013/00
A61M015/00
A61M016/10
B05D007/14
A61M016/00
B65D083/06

US Classification:

128/203150, 128/203120, 604/058000

Abstract:

Systems and methods are provided for conditioning packaged powders. According to one method, a receptacle is provided having an enclosed chamber that contains a powder. At least one pulse of energy is applied to the receptacle to increase the efficiency at which the powder may be extracted from the chamber when flowing a gas through the chamber.

US Patent:

20100112056, May 6, 2010

Filed:

Nov 4, 2008

Appl. No.:

12/264709

Inventors:

Andrea Rourke - San Mateo CA, US
Clark Allphin - Los Altos CA, US
Maura Murphy - Baltimore MD, US

International Classification:

A61K 9/36
A61K 9/28
A61K 9/30
A61K 31/19
A61P 25/00

US Classification:

424479, 424474, 424475, 514557

Abstract:

The present invention provides a pharmaceutical composition, presented as a solid unit dosage form adapted for oral administration of sodium oxybate. The preferred unit dosage form is a tablet comprising a relatively high weight-percentage of sodium oxybate, in combination with a relatively small weight-percentage of total excipients. This permits the tablets to contain/deliver a pharmaceutically effective amount, e.g., about 0.5-1.5 g of sodium oxybate in each tablet with a delivery profile similar to that of the liquid form. The tablets are bioequivalent to the liquid form.

US Patent:

20110111027, May 12, 2011

Filed:

May 4, 2010

Appl. No.:

12/773599

Inventors:

ANDREA MARIE ROURKE - BELMONT CA, US
MAURA PATRICIA MURPHY - BALTIMORE MD, US
JAMES FREDERICK PFEIFFER - OAKLAND CA, US
CLARK PATRICK ALLPHIN - LOS ALTOS CA, US
ALYA KHAN MCGINLAY - BELMONT CA, US

Assignee:

JAZZ PHARMACEUTICALS, INC. - Palo Alto CA

International Classification:

A61K 31/19
A61K 9/24
A61P 25/00
A61P 25/14

US Classification:

424472, 514557

Abstract:

The present invention provides a solid immediate release dosage form adapted for oral administration of GHB. The solid immediate release dosage form includes an immediate release formulation comprising a relatively high weight-percentage of GHB with a bioavailability similar to that of a liquid GHB dosage form.