- Lutherville MD, US Andrew A. Calabrese - Cockeysville MD, US
Assignee:
AgriMetis, LLC - Lutherville MD
International Classification:
C07H 17/00 A01N 43/90
Abstract:
Compositions including derivatives of spinosyns and methods for the production of derivatives of spinosyns are provided. The spinosyn derivatives described herein include those functionalized on the C-5,6 double bond to provide an aziridine ring system. The method produces spinosyn derivatives that exhibit activity towards insects, arachnids, and nematodes and are useful in the agricultural and animal health markets.
- Lutherville MD, US Andrew Calabrese - Lutherville MD, US
Assignee:
AGRIMETIS, LLC - Lutherville MD
International Classification:
C07H 17/08 A01N 45/02
Abstract:
Compositions including derivatives of spinosyns and methods for the production of derivatives of spinosyns are provided. The spinosyn derivatives described herein include spinosyn derivatives functionalized on the C5-C6 double bond of the spinosyn. The method produces spinosyn derivatives that exhibit activity towards insects, arachnids, and nematodes and are useful in the agricultural and animal health markets.
Substituted Triazole Derivatives As Oxytocin Antagonists
- Sandwich, GB Andrew Antony Calabrese - Cockeysville MD, US David Ellis - Sandwich, GB
International Classification:
C07D 401/14
Abstract:
The present invention relates to substituted triazoles of formula (I), uses thereof, processes for the preparation thereof and compositions containing said compounds. These inhibitors have utility in a variety of therapeutic areas including sexual dysfunction.
Deepcure
Head of Chemistry - Concurrent Role
Stealth Biotechs
Helping Good Peoeple Do Good Science - Concurrent Role
Achaogen Sep 1, 2016 - Mar 2019
Vice President of Chemistry
Agrimetis Llc Apr 2014 - Sep 2016
Vice President of Chemistry
Acidophil Llc Apr 2014 - Sep 2016
Vice President of Chemistry
Education:
Ucl 1997 - 1999
Doctorates, Doctor of Philosophy
Ucl 1996 - 1999
Doctorates, Doctor of Philosophy, Chemistry
University of Oxford 1992 - 1996
Masters, Master of Arts, Chemistry
Skills:
Drug Discovery Medicinal Chemistry Chemistry Drug Design Organic Synthesis Protein Chemistry Clinical Trials High Throughput Screening Change Management Hplc Science Small Molecules Target Identification Gpcrs Synthetic Chemistry
Goddard Inc.
Senior Mechanical Engineer
Boston Scientific Sep 2015 - Dec 2017
Senior Research and Development Engineer
Boston Scientific Apr 2011 - Sep 2015
Research and Development Engineer Ii
Dresser-Masoneilan Jul 2007 - Apr 2011
Product Engineer
Cambridge Tool & Mfg Dec 2006 - Jul 2007
Manufacturing Engineer
Education:
Wentworth Institute of Technology 2002 - 2006
Skills:
Solidworks Mechanical Engineering Machining Testing Design For Manufacturing Root Cause Analysis Medical Devices Control Valves Mechanical Drawings Tolerance Analysis Technical Documentation Manufacturing Engineering Injection Molding Manufacturing Research and Development Lean Manufacturing Engineering Product Development Rapid Prototyping Plastic Part Design Catheters Ultrasonic Welding Geometric Dimensioning and Tolerancing Technical Presentations Die Casting Plastic Extrusion Laser Welding Braiding Motorcycling Skiing Running Computer Aided Design Product Design