Andrew A Jayaraj

US Patent:

7902239, Mar 8, 2011

Filed:

Jul 9, 2007

Appl. No.:

11/774702

Inventors:

Albert C. Pierce - Cambridge MA, US
Michael Arnost - North Andover MA, US
Robert J. Davies - Arlington MA, US
Cornelia J. Forster - Pelham NH, US
Vincent Galullo - South Grafton MA, US
Ronald Grey, Jr. - Cambridge MA, US
Mark Ledeboer - Acton MA, US
Jinwang Xu - Framingham MA, US
Hayley Binch - Harwell, GB
Brian Ledford - Attleboro MA, US
David Messersmith - Somerville MA, US
Suganthi Nanthakumar - Newton MA, US
Andrew Jayaraj - Needham MA, US
Greg Henkel - Carlsbad CA, US
Francesco G. Salituro - Marlboro MA, US
Jian Wang - Newton MA, US

Assignee:

Vertex Pharmaceuticals Incorporated - Cambridge MA

International Classification:

A61K 31/541
A61K 31/55
A61K 31/4196
A61K 31/5377

US Classification:

514383, 5142275, 5142358, 51425405, 514326, 51421709

Abstract:

The present invention relates to inhibitors of protein kinases. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.

US Patent:

20040214817, Oct 28, 2004

Filed:

Nov 17, 2003

Appl. No.:

10/715111

Inventors:

Albert Pierce - Cambridge MA, US
Michael Amost - North Andover MA, US
Robert Davies - Arlington MA, US
Cornelia Forster - Pelham NH, US
Vincent Galullo - South Grafton MA, US
Ronald Grey - Cambridge MA, US
Mark Ledeboer - Acton MA, US
Jinwang Xu - Framingham MA, US
Hayley Binch - Harwell, GB
Brian Ledford - Attleboro MA, US
David Messersmith - Somerville MA, US
Suganthi Nanthakumar - Newton MA, US
Andrew Jayaraj - Needham MA, US
Greg Henkel - Carlsbad CA, US
Francesco Salituro - Marlboro MA, US
Jian Wang - Newton MA, US

International Classification:

C07D417/02
C07D413/02
C 07D 4 3/02
A61K031/55
A61K031/541
A61K031/5377
A61K031/4196

US Classification:

514/217090, 514/227500, 514/235800, 514/254050, 514/326000, 514/383000, 544/060000, 544/132000, 544/366000, 546/208000, 548/264800

Abstract:

The present invention relates to inhibitors of protein kinases. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.