Andrew A Thompson

US Patent:

6369247, Apr 9, 2002

Filed:

Sep 30, 1996

Appl. No.:

08/718408

Inventors:

Ross A. Miller - Fanwood NJ
Andrew S. Thompson - Mountainside NJ
Raman K. Bakshi - Edison NJ
Edward G. Corley - Old Bridge NJ

Assignee:

Merck Co., Inc. - Rahway NJ

International Classification:

C07J 900

US Classification:

552542, 552636, 540 2, 540106

Abstract:

The instant invention involves a process for oxidizing compounds containing an allylic group, i. e. those containing an allylic hydrogen or allylic alcohol group, to the corresponding enones, using a ruthenium-based catalyst in the presence of a hydroperoxide. Particularly, -5-steroidal alkenes can be oxidized to the corresponding -5-7-keto alkenes.

US Patent:

6639071, Oct 28, 2003

Filed:

Oct 19, 2001

Appl. No.:

10/000537

Inventors:

Louis S. Crocker - Belle Mead NJ
Andrew S. Thompson - Mountainside NJ
Christine Stelmach - Westfield NJ
Steven D. Young - Lansdale PA

Assignee:

Merck Co., Inc. - Rahway NJ

International Classification:

C07D26518

US Classification:

544 92

Abstract:

The instant invention describes a method for crystallizing (-)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-2H-3,1-benzoxazin-2-one from a solvent and anti-solvent system and producing the crystalline product. The desired final crystal form, Form I, can be produced when using methanol or ethanol. Form II is isolated from 2-propanol and can be converted to the desired crystal form at low drying temperatures, such as between about a temperature of 40Â C. and 50Â C.

US Patent:

6756416, Jun 29, 2004

Filed:

Feb 12, 2002

Appl. No.:

10/074606

Inventors:

Sharon A. Free - Wallingford PA
Vincenzo A. Bonaddio - Boothwyn PA
Andrew M. Thompson - West Chester PA
Joseph W. Lovette - Newark DE

Assignee:

Foamex L.P. - Linwood PA

International Classification:

C08G 1828

US Classification:

521172, 521110, 521112, 521130, 525123, 525127, 525453

Abstract:

An ester polyurethane foam is prepared by reacting a mixture of one or more polyester polyols with one or more isocyanates and one or more silicone surfactants in the presence of a blowing agent, such as water, and other additives, such as catalysts. The cured foam is chemically treated in a caustic solution to form a hydrophilic ester polyurethane foam having a water absorption rate of at least 20 pounds of water per square foot per minute, preferably at least 25 pounds of water per square foot per minute. The foam also has greater water holding capacity and wet strength than cellulose.

US Patent:

6939964, Sep 6, 2005

Filed:

Jun 24, 2004

Appl. No.:

10/891749

Inventors:

Louis S. Crocker - Belle Mead NJ, US
Andrew S. Thompson - Mountainside NJ, US
Christine Stelmach - Westfield NJ, US
Steven D. Young - Lansdale PA, US

Assignee:

Merck & Co., Inc. - Rahway NJ

International Classification:

C07D265/18

US Classification:

544 92

Abstract:

The instant invention describes a method for crystallizing (−)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-2H-3,1-benzoxazin-2-one from a solvent and anti-solvent solvent system and producing the crystalline product. The desired final crystal form, Form I, can be produced when using methanol or ethanol. Form II is isolated from 2-propanol and can be converted to the desired crystal form at low drying temperatures, such as between about a temperature of 40 C. and 50 C.

US Patent:

6994932, Feb 7, 2006

Filed:

Jun 28, 2002

Appl. No.:

10/183943

Inventors:

Mark R. Kinkelaar - Eddystone PA, US
Andrew Thompson - Eddystone PA, US

Assignee:

Foamex L.P. - Linwood PA

International Classification:

H01M 2/00

US Classification:

429 34, 429 12, 429 35

Abstract:

The present invention concerns a fuel reservoir for a liquid fuel cell particularly useful for portable electronic devices in which the fuel reservoir can deliver the liquid fuel regardless of the orientation. The fuel reservoir comprises (a) a container defining a cavity for holding the liquid fuel; (b) a wicking structure positioned within the cavity and into which at least a portion of the liquid fuel wicks and from which said liquid fuel subsequently may be discharged or delivered, such as by pumping or wicking. The wicking structure is formed from a wicking material with a free rise wick height greater than at least one half of the longest dimension of the wicking structure. Among materials with such wicking capability are foams, matted, bundled or woven fibers and nonwoven fibers. The container may have a generally flat and thin profile, formed as a pouch or envelope with substantially planar top and bottom faces of flexible film material, such that the container holding the wicking structure and filled with the liquid fuel can be bent or shaped.

US Patent:

7737306, Jun 15, 2010

Filed:

Oct 22, 2008

Appl. No.:

12/255951

Inventors:

Andrew Thompson - Mountainside NJ, US
Shawn Zhang - Stirling NJ, US
Lonnie Robarge - Seattle WA, US

Assignee:

Suterra, LLC - Los Angeles CA

International Classification:

C07C 45/00

US Classification:

568486, 568488

Abstract:

One or more embodiments of the invention are directed to the synthetic methods for making lepidopteran pheromones including navel orangeworm pheromones. The synthetic methods involve novel, efficient, and environmentally benign steps and procedures.

US Patent:

8115035, Feb 14, 2012

Filed:

Apr 20, 2010

Appl. No.:

12/763589

Inventors:

Andrew Thompson - Mountainside NJ, US
Xiongzhi Zhang - Stirling NJ, US
Lonnie Robarge - Seattle WA, US

Assignee:

Suterra, LLC - Los Angeles CA

International Classification:

C07C 45/00

US Classification:

568486, 568488

Abstract:

One or more embodiments of the invention are directed to the synthetic methods for making lepidopteran pheromones including navel orangeworm pheromones. The synthetic methods involve novel, efficient, and environmentally benign steps and procedures.

US Patent:

8309722, Nov 13, 2012

Filed:

Mar 12, 2008

Appl. No.:

12/531016

Inventors:

John Charles Tomesch - Succasunna NJ, US
Peng Li - New Milford NJ, US
Wei Yao - New Milford NJ, US
Qiang Zhang - Somerset NJ, US
James David Beard - New York NY, US
Andrew S. Thompson - Mountainside NJ, US
Hua Cheng - Plainsboro NJ, US

Assignee:

Intra-Cellular Therapies, Inc. - New York NY

International Classification:

C07D 241/36

US Classification:

544343, 546 85

Abstract:

The present invention provides methods for the preparation of substituted heterocycle fused gamma-carbolines, intermediates useful in producing them and methods for producing such intermediates and such heterocycle fused gamma-carbolines.