Andrzej K Drukier
age ~78
from Herndon, VA
- Also known as:
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- Andrzaj K Drukier
- Andrej Drukier
- Andy Drukier
- Andrze Drukier
- J R
Andrzej Drukier Phones & Addresses
- Herndon, VA
- Greenbelt, MD
- 5660 Oak Tanager Ct, Burke, VA 22015 • 7034259781 • 7035438014
- New York, NY
- 5660 Oak Tanager Ct, Burke, VA 22015 • 7038621276
Work
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Position:Building and Grounds Cleaning and Maintenance Occupations
Education
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Degree:Bachelor's degree or higher
Emails
Us Patents
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Supersensitive Immunoassays
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US Patent:7604956, Oct 20, 2009
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Filed:Feb 25, 2005
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Appl. No.:11/065347
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Inventors:Andrzej J. Drukier - Burke VA, US
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Assignee:BioTraces, Inc. - Herndon VA
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International Classification:G01N 33/53
G01N 33/534
G01N 33/535 -
US Classification:435 79, 435 791, 435 792, 435 794, 435 75, 436518, 436524, 436525, 436526, 436528, 436531, 436804
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Abstract:An assay exhibiting improved sensitivity for achieving a factor of ten times (10×) better sensitivity than current sensitivity levels achieved by prior-art immunoassays, as exemplified by ELISA. Three main implementations are described: IA/MPD, Super-ELISA and Reverse Geometry Immunoassay, including specific panel biomarker relationships for the early detection and recognition patterns of breast and prostate cancers. More sensitive immunoassays are achieved through a better understanding of sources of biological background, and by the rejection of particular sources thereof. Super-sensitive immunoassays permit measurement of blood sample biomarkers, and show distribution of low abundance proteins included relationships between cytokine non-Gaussian distributions, very large dynamic ranges and strong age dependence, and including new algorithms based on 2D correlations of studied biomarkers.
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Sequencing Duplex Dna By Mass Spectroscopy
view source -
US Patent:20020168642, Nov 14, 2002
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Filed:Mar 26, 2001
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Appl. No.:09/816673
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Inventors:Andrzej Drukier - Herndon VA, US
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International Classification:C12Q001/68
C07H021/04 -
US Classification:435/006000, 534/015000, 536/023100
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Abstract:For the determination of masses of macromolecular analytes with particular application to DNA sequencing by mass spectroscopy, novel strategies of sample preparation and labeling decrease macromolecule breakage, improve identification of population members, aid attainment of a single charge state for the heterogeneous analyte inputs, and increase the sensitivity of detection of the fractionated macromolecules.
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Enhanced Chromatography Using Multiphoton Detection
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US Patent:58540849, Dec 29, 1998
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Filed:Jul 12, 1996
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Appl. No.:8/679671
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Inventors:Andrzej K. Drukier - Burke VA
Roman Bielski - Coopersburg PA -
Assignee:BioTraces, Inc. - Fairfax VA
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International Classification:G01N 33533
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US Classification:436541
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Abstract:A method for detecting an analyte of interest present in a mixture at an ultralow concentration includes selecting a radioactive derivatizing agent comprising a multiphoton-emitting radioisotope moiety and a moiety reactive with the analyte of interest, the radioisotope moeity being bound to the derivatizing agent by a bond that is stable under the conditions employed in the other steps of the method, derivatizing the analyte of interest with the derivatizing agent, separating the analyte of interest from other components of the mixture by chromatography, and detecting the analyte of interest using multiphoton detection. The derivatizing step may be performed before or after fractionation. A radiophore for multiphoton emission enhanced chromatography has a first moeity bound to a multiphoton-emitting radioisotope, and a second moiety that is reactive with a functional group of an analyte of interest. The first moiety may be a benzene group having an alkoxy, amino, or thiol group, bound to a halogen radioisotope; a complexing agent able to form a stable complex with a metal radioisotope such as a lanthanide or heavy metal.
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Ultralow Background Multiple Photon Detector
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US Patent:58669078, Feb 2, 1999
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Filed:Jun 25, 1996
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Appl. No.:8/669970
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Inventors:Andrzej J. Drukier - Burke VA
Igor R. Sagdejev - Fairfax VA -
Assignee:BioTraces, Inc. - Herndon VA
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International Classification:G01T 1167
G01T 1172 -
US Classification:250366
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Abstract:An ultralow background multiphoton detectors device for radioisotopes has a background of about one count per day. Two opposed gamma and X-ray photon detectors each preferably include a scintillation crystal and a photomultiplier tube. Sandwiched between the detectors are a separator and a sample holder for a sample labelled with a radioisotope such as I. sup. 125. The detectors convert emissions from the radioisotope into electric output pulses which are then subjected to signal processing for pulse shape analysis, discrimination of coincident from non-coincident events, and quantification of the radioisotope. Detector materials and components are selected to minimize background, and are shielded from external radiation. The device may further be constructed to resolve and provide images of two dimensional sample arrays.
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Enhanced Chromatography Using Multiphoton Detection
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US Patent:62251325, May 1, 2001
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Filed:Dec 10, 1998
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Appl. No.:9/208495
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Inventors:Andrzej K. Drukier - Burke VA
Roman Bielski - Coopersburg PA -
Assignee:BioTraces, Inc. - Fairfax VA
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International Classification:G01N 33533
G01N 2176
G01N 33532
G01N 33536 -
US Classification:436541
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Abstract:A method for detecting an analyte of interest present in a mixture at an ultralow concentration includes selecting a radioactive derivatizing agent comprising a multiphoton-emitting radioisotope moiety and a moiety reactive with the analyte of interest, the radioisotope moeity being bound to the derivatizing agent by a bond that is stable under the conditions employed in the other steps of the method, derivatizing the analyte of interest with the derivatizing agent, separating the analyte of interest from other components of the mixture by chromatography, and detecting the analyte of interest using multiphoton detection. The derivatizing step may be performed before or after fractionation. A radiophore for multiphoton emission enhanced chromatography has a first moeity bound to a multiphoton-emitting radioisotope, and a second moiety that is reactive with a functional group of an analyte of interest. The first moiety may be a benzene group having an alkoxy, amino, or thiol group, bound to a halogen radioisotope; a complexing agent able to form a stable complex with a metal radioisotope such as a lanthanide or heavy metal.
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Array For A Nuclear Radiation And Particle Detector
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US Patent:50287869, Jul 2, 1991
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Filed:May 4, 1989
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Appl. No.:7/347017
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Inventors:Angela J. Da Silva - Vancouver, CA
Mark A. Le Gros - Vancouver, CA
Brian G. Turrell - Vancouver, CA
Andrzej Kotlicki - Warsaw, PL
Andrzej K. Drukier - Greenbelt MD -
Assignee:The University of British Columbia
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International Classification:H01L 3900
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US Classification:2503362
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Abstract:A cryogenic detector comprises an array formed from a plurality of spherical grains made of type I superconducting material arranged in a preselected pattern and each having a preselected size (generally less than about 100 microns in diameter). Also disclosed is a method of making such an array by depositing a film of selected thickness of type I superconducting material on a substrate, etching the film to provide an array formed by a plurality of discrete pixels, melting the pixels under conditions whereby the pixels are transformed into substantially spherical shape, and cooling to freeze the molten pixels into substantially spherical grains.
Name / Title
Company / Classification
Phones & Addresses
President
Bio Traces
Research & Development in Biotechnology
Research & Development in Biotechnology
13445 Sunrise Vly Dr #100, Herndon, VA 20171
7037931550, 7037931564
7037931550, 7037931564
Chairman of the Board
Biotraces Inc
Develop Biomedical Instruments
Develop Biomedical Instruments
13455 Snrs Val Dr S, Herndon, VA 20171
5660 Oak Tanager Ct, Springfield, VA 22015
2190 Fox Ml Rd SUITE 200, Herndon, VA 20171
7037931550
5660 Oak Tanager Ct, Springfield, VA 22015
2190 Fox Ml Rd SUITE 200, Herndon, VA 20171
7037931550
Andrzej Kamil Drukier
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