David Kent Herron - Indianapolis IN, US Sajan Joseph - Indianapolis IN, US Angela Lynn Marquart - Greenwood IN, US John Joseph Masters - Fishers IN, US David Mendel - Indianapolis IN, US Gerald Floyd Smith - Greenwood IN, US Philip Parker Waid - Indianapolis IN, US Michael Robert Wiley - Indianapolis IN, US Ying Kwong Yee - Carmel IN, US
This application relates to a compound of formula I (or a pharmaceutically acceptable salt thereof) as defined herein, pharmaceutical compositions thereof, and its use as an inhibitor of factor Xa, as well as a process for its preparation and intermediates therefor.
Substituted Heterocyclic Carboxamides With Antithrombotic Activity
David Kent Herron - Indianapolis IN, US Sajan Joseph - Indianapolis IN, US Angela Lynn Marquart - Greenwood IN, US John Joseph Masters - Fishers IN, US David Mendel - Indianapolis IN, US Gerald Floyd Smith - Greenwood IN, US Anne Louise Tebbe - Hamburg, DE Philip Parker Waid - Indianapolis IN, US Michael Robert Wiley - Indianapolis IN, US Ying Kwong Yee - Carmel IN, US
This application relates to a compound of formula (I) (or a pharmaceutically acceptable salt thereof) as defined herein, pharmaceutical compositions thereof, and its use as an inhibitor of factor Xa, as well as a process for its preparation and intermediates therefor.
Jeffry Bernard Franciskovich - Zionsville IN, US Theodore Goodson, Jr. - Indianapolis IN, US David Kent Herron - Indianapolis IN, US Angela Lynn Marquart - Greenwood IN, US John Joseph Masters - Fishers IN, US David Mendel - Indianapolis IN, US Leander Merritt - Indianapolis IN, US Andrew Michael Ratz - Zionsville IN, US Gerald Floyd Smith - Greenwood IN, US Michael Robert Wiley - Zionsville IN, US Ying Kwong Yee - Carmel IN, US
Assignee:
Eli Lilly and Company - Indianapolis IN
International Classification:
A61K 31/4427 C07D 417/12
US Classification:
514352, 5462707
Abstract:
This application relates to a compound of formula I (or a prodrug thereof or a pharmaceutically acceptable salt of the compound or prodrug thereof) as defined herein, pharmaceutical compositions thereof, and its use as an inhibitor of factor Xa and/or thrombin, as well as a process for its preparation and intermediates therefor.
Jeffry Bernard Franciskovich - Zionsville IN, US David Kent Herron - Indianapolis IN, US Jared Harris Linebarger - Indianapolis IN, US Angela Lynn Marquart - Greenwood IN, US John Joseph Masters - Fishers IN, US David Mendel - Indianapolis IN, US Leander Merritt - Indianapolis IN, US Andrew Michael Ratz - Zionsville IN, US Gerald Floyd Smith - Greenwood IN, US Leland Otto Weigel - Indianpolis IN, US Michael Robert Wiley - Zionsville IN, US Ying Kwong Yee - Carmel IN, US
Assignee:
Eli Lilly and Company - Indianapolis IN
International Classification:
A61K 31/4427 C07D 417/12
US Classification:
514352, 5462707
Abstract:
This application relates to a compound of formula I (or a prodrug thereof or a pharmaceutically acceptable salt of the compound or prodrug thereof) as defined herein, pharmaceutical compositions thereof, and its use as an inhibitor of factor Xa and/or thrombin, as well as a process for its preparation and intermediates therefor (I).
Jeffry Bernard Franciskovich - Zionsville IN, US David Kent Herron - Indianapolis IN, US Valentine Joseph Klimkowski - Carmel IN, US Angela Lynn Marquart - Greenwood IN, US John Joseph Masters - Fishers IN, US David Mendel - Indianapolis IN, US Andrew Michael Ratz - Zionsville IN, US Gerald Floyd Smith - Greenwood IN, US Michael Robert Wiley - Zionsville IN, US Ying Kwong Yee - Carmel IN, US
This application relates to a compound of formula (I) (or a pharmaceutically acceptable salt of the compound) as defined herein, pharmaceutical compositions thereof, and its use as an inhibitor of factor Xa and/or thrombin, as well as a process for its preparation and intermediates therefor.
Aromatic Ether Derivatives Useful As Thrombin Inhibitors
Ankush Baburao Argade - South San Francisco CA, US Theodore Goodson, Jr. - Indianapolis IN, US David Kent Herron - Indianapolis IN, US Sajan Joseph - Indianapolis IN, US Salvatore Donato Lepore - Del Ray Beach FL, US Angela Lynn Marquart - Greenwood IN, US John Joseph Masters - Fishers IN, US David Mendel - Indianapolis IN, US Leander Merritt - Indianapolis IN, US Andrew Michael Ratz - Zionsville IN, US Gerald Floyd Smith - Greenwood IN, US Anne Louise Tebbe - Spartanburg SC, US Michael Robert Wiley - Zionsville IN, US Ying Kwong Yee - Carmel IN, US
This application relates to a compound of formula (I) (or a pharmaceutically acceptable salt of the compound or prodrug thereof) as defined herein, pharmaceutical compositions thereof, and its use as an inhibitor of factor Xa and/or thrombin, as well as a process for its preparation and intermediates therefor. An example of a compound of formula (I) is (a).
Thomas Albert Engler - Indianapolis IN, US Timothy Paul Burkholder - Carmel IN, US Joshua Ryan Clayton - Cicero IN, US Clive Gideon Diefenbacher - Greenwood IN, US Kelly Wayne Furness - Avon IN, US James Robert Henry - Indianapolis IN, US Yihong Li - Carmel IN, US Sushant Malhotra - Indianapolis IN, US Angela Lynn Marquart - Greenwood IN, US Johnathan Alexander McLean - Indianapolis IN, US David Mendel - Indianapolis IN, US Jon Kevin Reel - Carmel IN, US Brian Raymond Berridge - Greenfield IN, US Charles Edward Ruegg - Indianapolis IN, US John Morris Sullivan - Greenfield IN, US
Assignee:
Eli Lilly and Company - Indianapolis IN
International Classification:
A61P 25/08 A61K 31/55 C07D 487/06
US Classification:
540220, 540561
Abstract:
The present invention provides kinase inhibitors of Formula I.
David Herron - Indianapolis IN, US Sajan Joseph - Indianapolis IN, US Angela Marquart - Greenwood IN, US John Masters - Fishers IN, US David Mendel - Indianapolis IN, US Gerald Smith - Greenwood IN, US Philip Waid - Indianapolis IN, US Michael Wiley - Indianapolis IN, US Ying Yee - Carmel IN, US
International Classification:
A61K031/5513
US Classification:
514/221000
Abstract:
This application relates to a compound of formula (I) (or a pharmaceutically acceptable salt thereof) as defined herein, pharmaceutical compositions thereof, and its use as an inhibitor of factor Xa, as well as a process for its preparation and intermediates therefor.
Belvil Elementary School St. Albans WV 1969-1972, Temple of Faith Christian School Cross Lanes WV 1973-1975, St. Albans Junior High School St. Albans WV 1976-1978
Community:
Kathy Barnes, Patrick Templeton, Rebecca Moore, Cindy Light
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