Ann M Griffith

US Patent:

48791148, Nov 7, 1989

Filed:

Dec 20, 1985

Appl. No.:

6/811505

Inventors:

Nicholas Catsimpoolas - Newton Centre MA
Ahmad R. Kamarei - Arlington MA
Ann L. Griffith - Newton Centre MA
Robert S. Sinn - New York NY

Assignee:

Angio-Medical Corporation - Avenue of the Americas NY

International Classification:

A61K 3512
A61K 742
A61K 732
A61K 706

US Classification:

424 95

Abstract:

36 Lipid extracts and lipid fractions from mammalian omenta containing mostly lipids are used cosmetically for skin conditions, skin care and cosmetic products which products have skin softening applications without skin irritation, greasiness or mutagenic effect. These materials with and without ganglioside are used for skin conditions such as keratosis, white spots and the like.

US Patent:

49218387, May 1, 1990

Filed:

Jun 16, 1987

Appl. No.:

7/062962

Inventors:

Nicholas Catsimpoolas - Newton Centre MA
Ann L. Griffith - Newton Centre MA
Robert S. Sinn - New York NY

Assignee:

Trustees of Boston University - Boston MA
Angio-Medical Corp. - New York NY

International Classification:

A61K 3170
A01N 4304
A01N 5700
C07J 0000

US Classification:

514 25

Abstract:

A method for enhancing angiogenesis and/or blood vascular perfusion in mammals by administering a pharmacologically effective amount of specific angiogenically active non-ionic, anionic, cationic and zwitterionic amphiphilic compounds. An angiogenically effective amount of the angiogenically active compound digitonin is in the range of at least 1. 25 microgram to at least 200 microgram of digitonin. The range including enhancement of vascular perfusion is up to 50 mg of digitonin.