- Richmond CA, US Anthony Conway - Emeryville CA, US
Assignee:
Sangamo Therapeutics, Inc. - Richmond CA
International Classification:
A61K 35/17 C12N 15/86
Abstract:
The present disclosure provides mammalian cells such as regulatory T cells containing a transgene in the FOXP3 genomic locus. Also provided are methods of generating the cells and methods of using the cells to treat patients in need of immunosuppression.
Methods And Compositions For Modification Of A Cystic Fibrosis Transmembrane Conductance Regulator (Cftr) Gene
The present disclosure is in the field of genome engineering, particularly targeted integration of a functional SCID-related genes (e.g., IL2RG, RAG1 and/or RAG2 gene) into an IL2RG gene of a cell for provision of proteins lacking or deficient in SCID.
- Richmond CA, US - Vancouver, CA Anthony Conway - Richmond CA, US Xinyao Du - Vancouver, CA Michael J. Hope - Vancouver, CA Michael C. Holmes - Richmond CA, US Gary K. Lee - Richmond CA, US Paulo Jia Ching Lin - Vancouver, CA Thomas Madden - Vancouver, CA Barbara Mui - Vancouver, CA
Described herein are lipid nanoparticles comprising cationic lipids and other lipids and also comprising engineered nucleases facilitate transfer of nucleic acids to cells.
"They're not going to be doing anything other than posturing before the election," said Anthony Conway, executive director of the Alliance of Nonprofit Mailers. "While I think Issa has the votes, it's a tough vote to take right before the election."