Kernel
Senior Principal Scientist
Mit Media Lab Jul 2015 - Apr 2017
Director of Bionic Neural Interface Group, Center For Extreme Bionics
Mit Media Lab Jan 2015 - Apr 2017
Research Scientist, Biomechatronics
Izentis Jan 2015 - Apr 2017
Senior Consultant
Mit Media Lab Jun 2013 - Dec 2014
Postdoctoral Associate, Synthetic Neurobiology Group
Education:
Massachusetts Institute of Technology 2009 - 2013
Doctorates, Doctor of Philosophy, Biotechnology, Engineering, Philosophy
Massachusetts Institute of Technology 2007 - 2009
Master of Science, Masters, Applied Physics, Engineering
Brown University 2003 - 2007
Bachelors, Bachelor of Science, Physics
Skills:
Fiber Optics Optics Spectroscopy Technology Reactive Ion Etching Pecvd Wet Chemical Etching Optical Microscopy Electrophysiology Photonics Photolithography Nanofabrication Numerical Analysis Numerical Simulation Plasma Etching Neuroscience Statistical Particle Tracking Velocimetry Matlab Holography Applied Physics Mems Biotechnology Focused Ion Beam Lithography Comsol Statistical Data Analysis Electric Propulsion Lifesciences Optogenetics Neurophotonics Microfluidics Ion Implantation Microfabrication Laser Physics Mass Spectrometry Systems Neuroscience Molecular Dynamics Plasma Physics Neurotechnology Nsf Propulsion Solidworks C/C++ Stl Electron Beam Evaporation Research Optical Engineering Science Astronautics Fluorescence Microscopy Neuroengineering Microscopy Bioengineering Nanotechnology Electrospray Ionic Liquids
Anthony Zorzos - Cambridge MA, US Clifton Fonstad - Arlington MA, US Edward Boyden - Cambridge MA, US August Dietrich - Somerville MA, US
Assignee:
MASSACHUSETTS INSTITUTE OF TECHNOLOGY - Cambridge MA
International Classification:
A61B 5/04
US Classification:
600544
Abstract:
According to principles of this invention, the photoelectrochemical effect (“PE effect”) may be greatly reduced or eliminated, even when an electrode is immersed in an electrolyte and exposed to light, by using a transparent conductor to record electrical activity. Thus, an electrode with a clear conductor may be used to accurately record electrical activity of neurons and other cells that are exposed to light in vivo or in vitro. Such an electrode eliminates or greatly reduces the artifacts that would otherwise be caused by light due to the PE effect.
Methods And Apparatus For Microstructure Lightguides
Anthony Zorzos - Cambridge MA, US Clifton Fonstad - Arlington MA, US Edward Boyden - Chestnut Hill MA, US Jacob Bernstein - Cambridge MA, US
Assignee:
MASSACHUSETTS INSTITUTE OF TECHNOLOGY - Cambridge MA
International Classification:
A61N 5/067 G02B 6/04 A61N 5/06
US Classification:
607 89, 385115, 362554, 607 92
Abstract:
This invention may be implemented as a microstructure probe for delivering light of variable color and/or power, via a set of integrated lightguides, from an optical source (or set of sources) to regions spatially arranged 3-dimensionally, with a length scale of microns to millimeters. In exemplary embodiments of this invention, a microstructure probe comprises many lightguides and is adapted to be inserted into neural or other tissue. The lightguides run in parallel along at least a portion of the axis of the probe. The probe may deliver light to many points along the axis of insertion of the probe.This invention may be implemented as an array of two or more such probes (each of which comprises multiple lightguides). This array may be used to deliver light to neural tissue in a complex 3D pattern.
Methods And Apparatus For High-Throughput Neural Screening
Edward Boyden - Chestnut Hill MA, US Jacob Bernstein - Cambridge MA, US Christian Wentz - Cambridge MA, US Michael Baratta - Boulder CO, US Brian Allen - Cambridge MA, US Anthony Zorzos - Cambridge MA, US Jorg Scholvin - Boston MA, US Clifton Fonstad - Arlington MA, US
Assignee:
MASSACHUSETTS INSTITUTE OF TECHNOLOGY - Cambridge MA
International Classification:
A61N 5/06
US Classification:
607 88
Abstract:
In exemplary implementations of this invention, high-throughput screening of a mammalian brain is performed to locate neural circuit targets of interest. A variety of search patterns may be used for this neural screening, including (a) iterative subdivision, (b) serial search, and (c) combinatorial. To perform this neural screening, an array of optical fibers (or an array of waveguides) is inserted into the brain. Alternately, the array is positioned adjacent to the brain. Each fiber or waveguide in the array is coupled to a light source (LED or laser). The brain has been previously sensitized to light, using genetically encoded optical neural control reagents, which are delivered either using viruses or via transgenic means. In the screening, the array is used to optically perturb the brain. For example, the neurons of the brain may be activated by one color of light, and/or silenced by another color of light.
Methods And Apparatus For Three-Dimensional Microfabricated Arrays
Jorg Scholvin - Cambridge MA, US Anthony Zorzos - Cambridge MA, US Clifton Fonstad - Arlington MA, US Edward Boyden - Chestnut Hill MA, US
Assignee:
Massachusetts Institute of Technology - Cambridge MA
International Classification:
G01R 1/073 B23K 20/00 C25D 3/00 H01R 4/02
US Classification:
439482, 439 78, 228101, 2281791, 205261
Abstract:
In exemplary implementations of this invention, electrical connections are fabricated between two orthogonal surfaces by electroplating. The two surfaces are separated (except for the electrical connections) by a gap of not more than 100 micrometers. Multiple electrical connections may be fabricated across the gap. In preparatory steps, conductive pads on the two surfaces may be separately electroplated to build up “bumps” that make it easier to bridge the remainder of the gap in a final plating step. Alternately, electroless deposition may be used instead of electroplating. In exemplary implementations, a 3D probe array may be assembled by inserting array structures into an orthogonal base plate. The array structures may be aligned and held in place, relative to the base plate, by mechanical means, including side hooks, stabilizers, bottom hooks, alignment parts and a back plate.
A nerve in a mammal is optogenetically transduced, wherein the nerve is susceptible to stimulus by selective application of transdermal light, and a light source is applied to dermis of the mammal at or proximate to the optogenetically transduced nerve, to thereby stimulate the nerve. A wearable device for optogenetic motor control and sensation restoration of a mammal includes a wearable support, a power source at the wearable support, a controller at the wearable support and in electrical communication with a power source, and a transdermal light source coupled to the controller.
Method And System For Providing Proprioceptive Feedback And Functionality Mitigating Limb Pathology
- Cambridge MA, US Tyler Clites - Cambridge MA, US Benjamin Maimon - Brookline MA, US Anthony Zorzos - Cambridge MA, US Matthew J. Carty - Quincy MA, US Jean-Francois Duval - Malden MA, US
Proprioceptive feedback is provided in a residual limb of a person that includes forming a linkage between a pair of agonist and antagonist muscles, forming a sliding surface over which the agonist and antagonist muscles slide. The sliding surface can include a synovial sleeve, a bridge formed between the distal ends of bones, or a fixture that is osseointegrated into the bone. The invention also includes a system for transdermal electrical communication in a person that includes a percutaneous access device, a sensory device that communicates signals between a muscle and the percutaneous device, and a stimulation device in communication with the percutaneous access device. In another embodiment, a closed-loop functional stimulation system restores lost functionality to a person that suffers from impairment of a neurological control system or at least partial loss of a limb.
Googleplus
Anthony Zorzos
Youtube
Gracie App - Demonstration Video
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31s
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3m 55s
"full of beauty and without subject," Sir Joh...
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4m 29s
New Techniques for Mapping the Brain - Ed Boy...
Dr. Ed Boyden at the BrainMind Summit hosted at Stanford, interviewed ...
Duration:
10m 5s
Ed Boyden: Neuroengineering - The Future is Now
Ed Boyden, Associate Professor, MIT Media Lab on optogenetics, and stu...
Duration:
21m 50s
Ed Boyden: A light switch for neurons
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