John S. Lazo - Pittsburgh PA Robert L. Rice - Glenshaw PA April Cunningham - Harleysville PA Peter Wipf - Pittsburgh PA
Assignee:
University of Pittsburgh - Pittsburgh PA
International Classification:
C07D26332
US Classification:
548236
Abstract:
The present invention is directed to compounds having the formula: ##STR1## The invention further provides a method of making the compounds. The compounds are useful as inhibitors of protein phosphatases, for example PP1, PP2A, PP3, CDC25A and CDC25B. The invention is further directed to a method of inhibiting a protein phosphatase, a method of inhibiting cell proliferation, and pharmaceutical compositions comprising the subject compounds.
John S. Lazo - Pittsburgh PA Robert L. Rice - Glenshaw PA April Cunningham - Harleysville PA Peter Wipf - Pittsburgh PA
Assignee:
University of Pittsburgh - Pittsburgh PA
International Classification:
A61K 3142
US Classification:
514374
Abstract:
The present invention is directed to compounds having the formula: ##STR1## The invention further provides a method of making the compounds. The compounds are useful as inhibitors of protein phosphatases, for example PP1, PP2A, PP3, CDC25A and CDC25B. The invention is further directed to a method of inhibiting a protein phosphatase, a method of inhibiting cell proliferation, and pharmaceutical compositions comprising the subject compounds.
John S. Lazo - Pittsburgh PA Robert L. Rice - Glenshaw PA April Cunningham - Harleysville PA Peter Wipf - Pittsburgh PA
Assignee:
University of Pittsburgh - Pittsburgh PA
International Classification:
A61K 3142 C07D26332
US Classification:
514374
Abstract:
The present invention is directed to compounds having the formula: ##STR1## The invention further provides a method of making the compounds. The compounds are useful as inhibitors of protein phosphatases, for example PP1, PP2A, PP3, CDC25A and CDC25B. The invention is further directed to a method of inhibiting a protein phosphatase, a method of inhibiting cell proliferation, and pharmaceutical compositions comprising the subject compounds.
The present invention is directed to compounds having the formula: ##STR1## The invention further provides a method of making the compounds. The compounds are useful as inhibitors of protein phosphatases, for example PP1, PP2A, PP3, CDC25A and CDC25B. The invention is further directed to a method of inhibiting a protein phosphatase, a method of inhibiting cell proliferation, and pharmaceutical compositions comprising the subject compounds.
Columbia SC Lancaster SC Douglasville GA Sharpsburg GA Haralson GA Jonesboro GA Riverdale GA Stockbridge GA Lithia Springs GA East Point GA
Work:
Palmetto Health - Patient Care Tech (2011) Sc Dept of Corrections - Med Tech/EMT (2007-2011) West Georgia Ambulance - EMT-I (2005-2007) All Med Transportation - CEO/Dispatch Supervisor (2003-2006) Rural Metro - EMT-I
Education:
Lithia Springs High - General Diploma, West Georgia Technical College - EMT-I, Turner Middle School, Harris Street Elementary
About:
I was born in early 1970. My life began 3 months before it should have and a Higher Power has kept me on Earth for the past 40 years. This will be about life lessons, the good, the bad, the ugly and i...
Tagline:
Meemaw's Interests
Bragging Rights:
Graduated from High School. Gained a National Registry of Emergency Medicine Certificate. Mother of 3. Meemaw of 1.
April Cunningham
Work:
Texas Tech University Undergraduate Admissions - Student Telecounselor (2010)
Education:
Texas Tech University - Broadcast Journalism
About:
"I love people who make me laugh. I honestly think it's the thing I like most, to laugh. It cures a multitude of ills. It's probably the most important thing in a person." - Audrey H...
April Cunningham
Education:
David Starr Jordan high
April Cunningham
About:
I'm a nurse, just decided to go back to school for my BSN and MSN. Have a few cats, lol.
Tagline:
Cranky nurse
April Cunningham
April Cunningham
April Cunningham
April Cunningham
Youtube
Merce Cunningham at 90
A kind of tribute to Merce Cunningham (Centralia (Washington), 16 apri...
Category:
Entertainment
Uploaded:
23 Aug, 2009
Duration:
8m 21s
US Ambassador Visit to Haifa, April 30, 2009
Ambassador James B. Cunningham visited Haifa in northern Israel on Apr...
Category:
Travel & Events
Uploaded:
26 May, 2009
Duration:
2m 41s
Chris Cunningham @ Manchester Opera House 22/...
Chris Cunningham and Friends Live at Manchester Opera House on Thursda...
Category:
Film & Animation
Uploaded:
03 May, 2010
Duration:
8m 22s
Meet Jake & April
Funny story... Jake & I talked before in 2016 when we both lived in Vi...