April A Rodriguez

US Patent:

20160002405, Jan 7, 2016

Filed:

Feb 26, 2014

Appl. No.:

14/770417

Inventors:

- Oakland CA, US
Jessica R. Kramer - Oakland CA, US
April R. Rodriguez - Marina Del Rey CA, US

International Classification:

C08G 69/48

Abstract:

Methods for preparation of novel amphiphilic derivatives of thioether containing block copolypeptides with narrow chain length distributions are described. These block copolymers can be chemically modified by oxidation and alkylation of the thioether containing residues. These materials generate self-assembled micelles, vesicles and hydrogels, or emulsions with oil phases. These assemblies can be used to encapsulate and delivery therapeutic molecules. The assemblies can be taken up by cells to release molecules from the assemblies.