Arlene E Howe

US Patent:

20220220160, Jul 14, 2022

Filed:

Dec 23, 2021

Appl. No.:

17/561332

Inventors:

- St. Louis MO, US
Todd A. Ciche - San Diego CA, US
Arlene R. Howe - Clarkson Valley MO, US
Stephanie C. Waldheuser - St. Louis MO, US
Kimberly M. Wegener - St. Louis MO, US

International Classification:

C07K 14/325
A01N 63/50
A01P 7/04
C12N 15/82

Abstract:

Pesticidal proteins exhibiting toxic activity against Lepidopteran pest species are disclosed, and include, but are not limited to, TIC13085 and TIC13087. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding one or more of the disclosed pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding the pesticidal proteins of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the present invention in a biological sample, and methods of controlling Lepidopteran species pests using any of the TIC13085 and TIC13087 pesticidal proteins are also provided.