Phasebio Pharmaceuticals, Inc. Jan 1, 2009 - 2017
Member Board of Directors
Rodeo Therapeutics Jan 1, 2009 - 2017
Member Board of Directors
Fusion Pharmaceuticals Jan 1, 2009 - 2017
Member Board of Directors
Protagonist Therapeutics 2013 - Jul 2016
Member Board of Directors
Apogen Biotechnologies, Inc. 2013 - Jul 2016
Member Board of Directors
Education:
The Wharton School 2001 - 2003
Master of Business Administration, Masters, Entrepreneurship, Finance
The Johns Hopkins University 1996 - 1998
University of Houston 1991 - 1996
Doctorates, Doctor of Philosophy, Chemical Engineering
Indian Institute of Technology, Kanpur 1987 - 1991
Bachelors, Bachelor of Technology, Chemical Engineering
Us Patents
Nucleic Acid Sequences And Methods For Identifying Compounds That Affect Rna/Rna Binding Protein Interactions And Mrna Functionality
Disclosed herein are nucleic acid sequences and their optimized subfragments which are located in the mRNA untranslated regions of therapeutically-relevant genes. These sequences specifically bind RNA binding proteins (RBPs) and/or regulate the mRNA functionality. Also disclosed are methods of optimizing a subfragment of a parent nucleic acid sequence such that the RBP binding activity or mRNA functionality of the parent nucleic acid sequence is preserved in the optimized subfragment.
Nucleic Acid Sequences And Methods For Identifying Compounds That Affect Rna/Rna Binding Protein Interactions And Mrna Functionality
Disclosed herein are nucleic acid sequences and their optimized subfragments which are located in the mRNA untranslated regions of therapeutically-relevant genes. These sequences specifically bind RNA binding proteins (RBPs) and/or regulate the mRNA functionality. Also disclosed are methods of optimizing a subfragment of a parent nucleic acid sequence such that the RBP binding activity or mRNA functionality of the parent nucleic acid sequence is preserved in the optimized subfragment.
Nucleic Acid Sequences And Methods For Identifying Compounds That Affect Rna/Rna Binding Protein Interactions And Mrna Functionality
ANTHONY GIORDANO - PHOENIXVILLE PA, US ASISH XAVIER - WEST CHESTER PA, US
International Classification:
C12Q 1/68 C07H 21/04 C07H 21/02 G01N 33/53
US Classification:
435 6, 536 231, 436 94, 436501
Abstract:
Disclosed herein are nucleic acid sequences and their optimized subfragments which are located in the mRNA untranslated regions of therapeutically-relevant genes. These sequences specifically bind RNA binding proteins (RBPs) and/or regulate the mRNA functionality. Also disclosed are methods of optimizing a subfragment of a parent nucleic acid sequence such that the RBP binding activity or mRNA functionality of the parent nucleic acid sequence is preserved in the optimized subfragment.
Nucleic Acid Sequences And Methods For Identifying Compounds That Affect Rna/Rna Binding Protein Interactions And Mrna Functionality
Anthony Giordano - Phoenixville PA, US Asish Xavier - West Chester PA, US
International Classification:
C12Q001/68 C07H021/04 C12P019/34
US Classification:
435/006000, 435/091100, 536/023200
Abstract:
Disclosed herein are nucleic acid sequences and their optimized subfragments which are located in the mRNA untranslated regions of therapeutically-relevant genes. These sequences specifically bind RNA binding proteins (RBPs) and/or regulate the mRNA functionality. Also disclosed are methods of optimizing a subfragment of a parent nucleic acid sequence such that the RBP binding activity or mRNA functionality of the parent nucleic acid sequence is preserved in the optimized subfragment.
Name / Title
Company / Classification
Phones & Addresses
Asish Xavier Director
PhaseBio Pharmaceuticals Biotechnology · Commercial Physical Research
1 Great Vly Pkwy SUITE 30, Malvern, PA 19355 6109816500
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