Abbott Biotherapeutics Corporation - Redwood City, CA Apr 2010 - Dec 2012
Principal Research Scientist
Facet Biotech (A subsidiary of Abbott Labs) - Redwood City, CA Jan 2005 - Apr 2010
Senior Scientist
PDL BioPharma Inc - Red Wood City, CA Jun 2003 - Dec 2004
Staff Scientist
Protein Design Labs Inc - Fremont, CA Jun 2000 - Jun 2003
Staff Scientist
The Scripps Research Institute - La Jolla, CA Aug 1995 - Jun 2000
Senior Post Doctoral Fellow
Education:
Memorial University of Newfoundland 1990 - 1995
Ph.D., Immunology
Indian Veterinary Research Institute, India 1986 - 1989
MVSc, Veterinary Immunology
Acharya N.G. Ranga Agricultural University, India 1981 - 1986
BVSc &AH (DVM Equivalent), Veterinary Medicine
Skills:
Immunology and Oncology Research Project Management Research Project Clinical Trials Cro Immune Cell Targeting Target Discovery Animal Models Biomarker Development Autoimmune Diseases Clinical Research Biotechnology Immunology Immunology and Oncology Biologics Team Leadership San Translational Research Target Validation In Vivo Animal Models Cell Based Assays Pharmacology Flow Cytometry Immune Modulation Biomarker Discovery Biopharmaceuticals
Abbott Biotherapeutics Redwood City, CA Apr 2010 to Dec 2012 Principal Research ScientistTranslational Research, Facet Biotech Redwood City, CA Nov 2007 to Apr 2010 Senior ScientistTranslational Research, PDL Biopharma Inc Fremont, CA Jan 2005 to Nov 2007 Staff ScientistTarget Validation, Protein Design Labs Inc Fremont, CA Jun 2003 to Dec 2004 Staff ScientistProtein Design Labs Inc Fremont, CA Jun 2000 to Jun 2003 Staff Scientist, Division of Autoimmune and Inflammatory Diseases
Skills:
Cellular Immunology Target Discovery and Validation Immune Modulation Monoclonal Antibody Generation BioTherapeutics and Small Molecule Inhibitors Immunohistochemistry Gene Expression Profiling Multicolor Flowcyometry Cell based Assays In Vivo Mouse Models In Vitro Pre-clinical Studies Biomarker Assays Translational Research Immune Monitoring in Clinical Trials Outsourcing and Management of Studies to CROs Leadership and Managerial Skills
Us Patents
Treatment Of Inflammatory Bowel Diseases With Anti-Ip-10 Antibodies
Balaji Balasa - Union City CA, US Naoya Tsurushita - Palo Alto CA, US Nicholas F. Landolfi - Menlo Park CA, US
International Classification:
A61K 39/395 A61P 29/00 C07K 16/00 C07K 16/24
US Classification:
4241581, 4241301, 5303871, 5303873, 5303881
Abstract:
The present invention is directed to high affinity anti-human IP- antibodies or antigen-binding fragments of these antibodies, including chimeric, humanized or fully human antibodies. The present invention is also directed to a method of reducing the severity of at least one symptom of an inflammatory bowel disease in a subject in need thereof comprising administering to said subject an effective amount of an antagonist of IP-10, including the antibodies or antibody fragments of the present invention.
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