Barbara R Potts

US Patent:

7166634, Jan 23, 2007

Filed:

Jan 21, 2005

Appl. No.:

11/040923

Inventors:

Scott S. Mitchell - San Carlos CA, US
Kin S. Lam - San Diego CA, US
Jennifer Grodberg - Carlsbad CA, US
Barbara C. Potts - Escondido CA, US
Ginger Tsueng - San Diego CA, US
Donald J. White - San Deigo CA, US
Katherine Anne Reed - San Diego CA, US

Assignee:

Nereus Pharmaceuticals, Inc. - San Diego CA

International Classification:

A01N 43/38
A01N 43/36
C07D 209/10

US Classification:

514414, 548453, 548455

Abstract:

Compounds of Formula I, commonly referred to as bis-indole pyrroles, including isolated naturally-occurring compounds, synthetic and semi-synthetic derivatives thereof having antimicrobial properties and to antimicrobial compositions that include one or more of bis-indole pyrroles and their derivatives or analogs having antimicrobial properties are disclosed. Pharmaceutical compositions comprising such compounds and methods of treating bacterial infections with the disclosed compounds or the disclosed pharmaceutical compositions are also disclosed.

US Patent:

7375129, May 20, 2008

Filed:

Nov 20, 2006

Appl. No.:

11/602869

Inventors:

Scott S. Mitchell - San Carlos CA, US
Kin S. Lam - San Diego CA, US
Jennifer Grodberg - Carlsbad CA, US
Barbara C. Potts - Escondido CA, US
Ginger Tsueng - San Diego CA, US
Donald J. White - San Deigo CA, US
Katherine Anne Reed - San Diego CA, US

Assignee:

Nereus Pharmaceuticals, Inc. - San Diego CA

International Classification:

A61K 31/4025
A61K 31/404
C07D 209/10

US Classification:

514414, 548453, 548455, 514422

Abstract:

Compounds of Formula I, commonly referred to as bis-indole pyrroles, including isolated naturally-occurring compounds, synthetic and semi-synthetic derivatives thereof having antimicrobial properties and to antimicrobial compositions that include one or more of bis-indole pyrroles and their derivatives or analogs having antimicrobial properties are disclosed. Pharmaceutical compositions comprising such compounds and methods of treating bacterial infections with the disclosed compounds or the disclosed pharmaceutical compositions are also disclosed.