Barbara L Simpson

US Patent:

43339190, Jun 8, 1982

Filed:

Dec 15, 1980

Appl. No.:

6/216404

Inventors:

John W. Kleber - Indianapolis IN
Barbara E. Simpson - Indianapolis IN

Assignee:

Eli Lilly and Company - Indianapolis IN

International Classification:

A61K 922
A61K 926

US Classification:

424 15

Abstract:

Controlled release formulations comprised of a growth promoting agent admixed with a copolymer derived from lactic acid and glycolic acid and which is substantially free of polymerization catalyst are effective in the prolonged growth promotion of ruminants. A method for continuous dosing of active ingredients to a ruminant is provided.

US Patent:

44166591, Nov 22, 1983

Filed:

Nov 9, 1981

Appl. No.:

6/319183

Inventors:

Barbara E. Simpson - Indianapolis IN
Norman A. Gervais - Hardy VA

Assignee:

Eli Lilly and Company - Indianapolis IN

International Classification:

A61M 700

US Classification:

604 48

Abstract:

A sustained release capsule for introduction through the esophagus to the rumen of a ruminant has a tubular barrel containing a body of active composition urged by a piston and spring into sealing engagement with a constriction end wall shaped with a peripheral curved border leading to a frustoconical portion defining a delivery opening, the shape and width of such wall controlling the release rate to the rumen. The open front end of the barrel is closed by a hemispherical cap connected at the center of its convex outer face to a wing having opposite arms normally outstanding at near 90. degree. from the capsule body but resiliently bendable over a long arc along the convex face of the cap to retracted positions for introduction of the capsule through the esophagus. In the rumen, the arms return to near 90. degree. positions to hinder regurgitation of the capsule and to better withstand working and contractions of the rumen.

US Patent:

D2716232, Nov 29, 1983

Filed:

Apr 27, 1981

Appl. No.:

6/258223

Inventors:

Barbara E. Simpson - Indianapolis IN
Norman A. Gervais - Hardy VA

Assignee:

Eli Lilly and Company - Indianapolis IN

International Classification:

D2801

US Classification:

D28 2