Benjamin L Miller

age ~45

from Conway, SC

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Also known as:

Benjamin Leigh Miller
Ben L Miller

Phone and address:: 3313 Longwood Ln, Conway, SC 29527
8437333103

Connected to:

Benjamin Miller Phones & Addresses

3313 Longwood Ln, Conway, SC 29527 • 8437333103
143 Squire Dr, Rochester, NY 14623
4243 Reservoir Rd, Geneseo, NY 14454
Eden, NY

Us Patents

Oligocycloalkanoid Compounds And Methods Of Use
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US Patent:

6562782, May 13, 2003
Filed:

May 10, 2000
Appl. No.:

09/568403
Inventors:

Benjamin L. Miller - Rochester NY
Robert D. Hubbard - Rochester NY
Assignee:

University of Rochester - Rochester NY
International Classification:

A61K 31015
US Classification:

514 2, 514414, 514419, 514533, 514548, 514563, 514572, 514573, 514574, 514601, 514619, 514623, 514691, 514715, 514729, 530300, 548455, 548496, 560 40, 560173, 562499, 564 82, 564 84, 564 98, 564152, 564153, 564155, 564159, 564188, 568367, 568664, 568816
Abstract:

The present invention related to an oligocycloalkanoid compound comprising formula (I) wherein m, n, and o are independently an integer from 0 to 2; A through A are independently a direct link, alkylene, alkylene-Oâ, carbonyl, oxygen, or sulfur; X and Y are independently hydrogen, hydroxy, alkyl, or in combination an electrophilic group; and R through R are independently hydrogen, hydroxy, alkyl, alkenyl, alkynyl, substituted or unsubstituted aryl, N-, S-, or O-heterocycles, fused or multi-ring aryl with or without hetero ring members, arylalkyl, arylalkenyl, arylalkynyl, alkylphenyl, alkenylphenyl, alkynylphenyl, alkoxy, alkenyloxy, alkynyloxy, substituted or unsubstituted aryloxy, substituted or unsubstituted arylalkoxy, alkylacyl, alkenylacyl, alkynylacyl, arylacyl, aroyl, alkylaroyl, aminoaroyl, aminoalkylacyl, aminoalkyl, aminoalkenyl, aminoalkynyl, amino, alkylamino, alkenylamino, alkynylamino, arylamino, dialkylamino, dialkenylamino, dialkynylamino, arylalkylamino, arylalkenylamino, imino, alkylimino, alkenylimino, alkynylimino, arylimino, thiol, sulfoxide, alkyl sulfonamide, alkenyl sulfonamide, alkynyl sulfonamide, aryl sulfonamide, alkyl sulfonate ester, alkenyl sulfonate ester, alkynyl sulfonate ester, aryl sulfonate ester, amino acid, or polypeptide, with at least one of R through R and at least one of R through R being other than hydrogen. Also disclosed are a pharmaceutical composition including an oligocycloalkanoid compound of the present invention, and methods of using such compounds or compositions for treating a bacterial infection, inhibiting or treating septic shock, treating a disease caused by bacterial endotoxin, and inhibiting the activity of cathepsin K.

Biphasic Reaction Vessel And Methods Of Use
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US Patent:

6599754, Jul 29, 2003
Filed:

Apr 20, 2001
Appl. No.:

09/838971
Inventors:

Benjamin L. Miller - Rochester NY
Bryan Klekota - Del Mar CA
Assignee:

University of Rochester - Rochester NY
International Classification:

C01N 118
US Classification:

436178, 436177, 436501, 436514
Abstract:

A reaction vessel and method of identifying a ligand having affinity for a target molecule are disclosed. The reaction vessel includes a first member defining a first chamber, the first chamber including an organic solvent and a plurality of reactants which form a combinatorial library of products; a second member defining a second chamber, the second chamber including a target molecule and an aqueous solvent immiscible in the organic solvent; and a semipermeable membrane separating the contents of the first chamber from the contents of the second chamber, wherein said semipermeable membrane is permeable to one or more products of the combinatorial library of products.

Microcavity Biosensor And Uses Thereof
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US Patent:

7226733, Jun 5, 2007
Filed:

Feb 21, 2002
Appl. No.:

10/082634
Inventors:

Selena Chan - Sunnyvale CA, US
Philippe M. Fauchet - Pittsford NY, US
Scott R. Horner - Rochester NY, US
Benjamin L. Miller - Rochester NY, US
Assignee:

University of Rochester - Rochester NY
International Classification:

C12Q 1/68
C12M 1/00
G01N 16/06
C07H 21/04
US Classification:

435 6, 435 71, 435174, 4352831, 4352878, 4352887, 422 681, 422 8205, 536 231, 536 243, 530300, 530350
Abstract:

A biological sensor which includes: a porous semiconductor structure comprising a central layer interposed between upper and lower layers, each of the upper and lower layers including strata of alternating porosity; and one or more probes coupled to the porous semiconductor structure, the one or more probes binding to a target molecule, whereby a detectable change occurs in a refractive index of the biological sensor upon binding of the one or more probes to the target molecule. Methods of making the biological sensor and methods of using the same are disclosed, as is a detection device which includes such a biological sensor.

Method For Biomolecular Sensing And System Thereof
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US Patent:

7292349, Nov 6, 2007
Filed:

Oct 28, 2002
Appl. No.:

10/282274
Inventors:

Benjamin Miller - Rochester NY, US
Lewis Rothberg - Pittsford NY, US
Assignee:

University of Rochester - Rochester NY
International Classification:

G01B 9/02
US Classification:

356504, 356632
Abstract:

A sensing system and method for biomolecular sensing. The system includes: a receptor for the at least one target, the receptor including a substrate and a transparent coating on the substrate having front and back surfaces; a light source positioned to direct at least a portion of light from the light source toward the coating on the receptor; and a detector positioned to capture the light reflected from the front and back surfaces of the coating, the detector identifying presence of at least one target based on a change in the interference pattern of captured light.

Method Of Identifying Hairpin Dna Probes By Partial Fold Analysis
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US Patent:

7442510, Oct 28, 2008
Filed:

Oct 27, 2006
Appl. No.:

11/553904
Inventors:

Benjamin L. Miller - Penfield NY, US
Christopher M. Strohsahl - Saugerties NY, US
Assignee:

University of Rochester - Rochester NY
International Classification:

C12Q 1/68
C07H 21/02
C07H 21/04
US Classification:

435 6, 536 231, 536 243
Abstract:

Methods of identifying molecular beacons in which a secondary structure prediction algorithm is employed to identify oligonucleotide sequences within a target gene having the requisite hairpin structure. Isolated oligonucleotides, molecular beacons prepared from those oligonucleotides, and their use are also disclosed.

Method Of Identifying Hairpin Dna Probes By Partial Fold Analysis
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US Patent:

7598034, Oct 6, 2009
Filed:

Jan 3, 2005
Appl. No.:

10/584875
Inventors:

Benjamin L. Miller - Penfield NY, US
Christopher M. Strohsahl - Saugerties NY, US
Assignee:

University of Rochester - Rochester NY
International Classification:

C12Q 1/68
C07H 21/00
C07H 21/02
C07H 21/04
US Classification:

435 6, 536 221, 536 231, 536 243
Abstract:

Method of identifying molecular beacons in which a secondary structure prediction algorithm is employed to identify oligonucleotide sequences within a target gene having the requisite hairpin structure. Isolated oligonucleotides, molecular beacons prepared from those oligonucleotides, and their use are also disclosed.

Hybridization-Based Biosensor Containing Hairpin Probes And Use Thereof
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US Patent:

7811764, Oct 12, 2010
Filed:

Aug 14, 2007
Appl. No.:

11/838616
Inventors:

Benjamin L. Miller - Penfield NY, US
Christopher M. Strohsahl - Rochester NY, US
Assignee:

University of Rochester - Rochester NY
International Classification:

C12Q 1/68
C07H 21/02
C07H 21/04
US Classification:

435 6, 536 231, 536 243
Abstract:

A sensor chip that includes: a fluorescence quenching surface; a nucleic acid probe that contains first and second ends with the first end bound to the fluorescence quenching surface, and is characterized by being able to self-anneal into a hairpin conformation; and a first fluorophore bound to the second end of the first nucleic acid molecule. When the first nucleic acid molecule is in the hairpin conformation, the fluorescence quenching surface substantially quenches fluorescent emissions by the first fluorophore; and when the first nucleic acid molecule is in a non-hairpin conformation, fluorescent emissions by the fluorophore are substantially free of quenching by the fluorescence quenching surface. Various nucleic acid probes, methods of making the sensor chip, biological sensor devices that contain the sensor chip, and their methods of use are also disclosed.

Arrayed Imaging Reflectometry (Air) Sensor Chip Comprising Virus-Like Particles Suitable For The Detection Of Antiviral Immune Responses
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US Patent:

8450056, May 28, 2013
Filed:

May 1, 2009
Appl. No.:

12/434298
Inventors:

Benjamin L. Miller - Penfield NY, US
Tim R. Mosmann - Pittsford NY, US
Robert C. Rose - Geneseo NY, US
Charles R. Mace - Auburn NY, US
Assignee:

University of Rochester - Rochester NY
International Classification:

C12Q 1/70
G01N 33/552
G01N 33/549
G01N 21/00
G01B 9/02
US Classification:

435 5, 436527, 436532, 436164, 422 8205, 356450, 4241861, 4241991, 4242041, 4242061, 4242081, 4242111
Abstract:

A sensor chip for detecting an immune response against a virus, the sensor chip including a substrate having a surface and a plurality of virus-like particles or capsid fragments bound to discrete locations on the surface of the substrate. Detection devices containing the sensor chip and methods of detecting anti-viral immune responses are also described herein.

Resumes

Benjamin Miller Granbury, TX

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Work:

RIT Kinect Surfaces Research Grant
Rochester, NY
2011 to 2012
Mini Project Lead Augmented Reality Golf Project
Rochester, NY
2010 to 2011
Modeler

Education:

Rochester Institute of Technology
Rochester, NY
2009 to 2013
B.F.A. in 3D Digital Graphics

Skills:

3d modeling (Maya), texturing (Photoshop, Mudbox, Crazybump), sculpting (Mudbox), rendering (Maya),High and Low poly modeling, Hard surface and Organic modeling, Unreal Development Kit, Motion builder, After Effects, MEL and Python