Benjamin Hallett Ross

US Patent:

8236348, Aug 7, 2012

Filed:

Feb 4, 2004

Appl. No.:

10/772781

Inventors:

Jerry B. Gin - Sunnyvale CA, US
Benjamin F. Ross - Santa Clara CA, US

Assignee:

Bennes, Inc. - Sunnyvale CA

International Classification:

A61K 9/20
A61K 9/00
A61K 8/00
A61K 36/534

US Classification:

424464, 424 49, 424400, 424480, 424725, 424747, 433215, 514959

Abstract:

Flavored dosage forms, e. g. , lozenges and gums, are provided for sustained release of a flavoring agent in the mouth. The dosage forms provide sustained release by virtue of a wet matrix formed by admixture of a biocompatible, hydrophilic, water-insoluble polymer such as ethylcellulose and a flavoring agent, particularly an essential oil or a constituent thereof, e. g. , a terpene or sesquiterpene. The dosage forms may also include a second beneficial agent in addition to the flavoring agent. Exemplary such beneficial agents include ionizable zinc compounds and other cold remedies, local anesthetic and anti-infective agents, diet aids, fluoride-releasing compounds, and nicotine. The dosage forms, when formulated as lozenges, may be somewhat adhesive or substantially nontacky, depending primarily on the molecular weight of the hydrophilic polymer. Adhesive lozenges can serve as dosage forms that adhere to the teeth or gums for delivery of a beneficial agent thereto. Methods for using the dosage forms to provide sustained release of a flavoring agent and optionally deliver a second beneficial agent are also provided, as are methods for treating the common cold, treating a sore throat, facilitating weight loss, and assisting in smoking cessation.

US Patent:

20040151771, Aug 5, 2004

Filed:

Feb 4, 2003

Appl. No.:

10/358602

Inventors:

Jerry Gin - Sunnyvale CA, US
Benjamin Ross - Santa Clara CA, US

International Classification:

A61K009/20
A61K009/22
A61K035/78

US Classification:

424/468000, 424/725000

Abstract:

Flavored dosage forms, e.g., lozenges and gums, are provided for sustained release of a flavoring agent in the mouth. The dosage forms provide sustained release by virtue of a wet matrix formed by admixture of a biocompatible, hydrophilic, water-insoluble polymer such as ethylcellulose and a flavoring agent, particularly an essential oil or a constituent thereof, e.g., a terpene or sesquiterpene. The dosage forms may also include a second beneficial agent in addition to the flavoring agent. Exemplary such beneficial agents include ionizable zinc compounds and other cold remedies, local anesthetic and anti-infective agents, diet aids, fluoride-releasing compounds, and nicotine. The dosage forms, when formulated as lozenges, may be somewhat adhesive or substantially nontacky, depending primarily on the molecular weight of the hydrophilic polymer. Adhesive lozenges can serve as dosage forms that adhere to the teeth or gums for delivery of a beneficial agent thereto. Methods for using the dosage forms to provide sustained release of a flavoring agent and optionally deliver a second beneficial agent are also provided, as are methods for treating the common cold, treating a sore throat, facilitating weight loss, and assisting in smoking cessation.

US Patent:

20090081291, Mar 26, 2009

Filed:

Sep 26, 2007

Appl. No.:

11/904420

Inventors:

Jerry B. Gin - Sunnyvale CA, US
Benjamin F. Ross - Santa Clara CA, US

International Classification:

A61K 31/135
A61K 31/00
A61K 31/185
A61K 31/34
A61K 31/40
A61K 31/415
A61K 31/44
A61K 31/555
A61K 31/60
A61K 33/32
A61K 36/534
A61K 36/54
A61K 36/61
A61K 36/752
A61K 9/22
A61P 43/00

US Classification:

424468, 42419518, 424641, 424736, 424739, 424742, 424747, 514165, 514188, 514343, 514397, 514419, 514474, 514578, 514646

Abstract:

Aspects of the invention include a sustained release dosage form that can be administered to an oral cavity, e.g., the mouth. In certain embodiments, the sustained release dosage form is formulated as a lozenge or gum that may be administered to an oral cavity of a user for the purpose of dissolving over a prolonged period of time and thereby delivering an essential oil component therein. In certain embodiments, the sustained release dosage form includes a beneficial agent and, therefore, not only provides for the prolonged delivery of an essential oil component to an oral cavity, but also provides for the sustained release of a beneficial agent thereto. In certain embodiments, the sustained release dosage form includes a biocompatible, water-insoluble polymer, e.g., ethylcellulose and an essential oil component, which are combined in such a manner so as to produce a dosage form that substantially dissolves over a prolonged period of time when positioned within an aqueous environment, such as an oral cavity of a user. In certain embodiments, the sustained release dosage form may include an additional water soluble agent, such as gum arabic, which may be included so as to further provide the dosage form with a desired dissolution characteristic. In certain embodiments, the dosage form may also include a beneficial agent to be delivered to the mouth. Methods of formulating such dosage forms and administering them to an oral cavity for the treatment of an adverse condition are also provided herein.

US Patent:

20090081294, Mar 26, 2009

Filed:

Sep 26, 2007

Appl. No.:

11/904333

Inventors:

Jerry B. Gin - Sunnyvale CA, US
Benjamin F. Ross - Santa Clara CA, US

International Classification:

A61K 36/534
A61K 47/38
A61K 9/10
A61K 36/61
A61P 1/00
A61K 31/315
A61K 36/54
A61K 36/752

US Classification:

424486, 514781, 424488, 424736, 424776, 424747, 424739, 514494, 424742

Abstract:

Aspects of the invention include a sustained release dosage form that can be administered to an oral cavity, e.g., the mouth. In certain embodiments, the sustained release dosage form is formulated as a lozenge or gum that may be administered to an oral cavity for the purpose of providing lubrication therein. In certain embodiments, the sustained release dosage form not only provides lubrication to a mucosal surface of an oral cavity, but also provides for the sustained release of a flavoring and/or beneficial agent. Accordingly, in certain embodiments, the sustained release dosage form includes a water-insoluble polymer, e.g., ethylcellulose, an essential oil component, and an effective amount of a film forming binder, e.g., xanthan gum. In certain embodiments, the effective amount of the film forming binder and the type of film forming binder are selected so as to provide the sustained release dosage with the capability of lubricating one or more mucosal surfaces within an oral cavity when the dosage form is positioned therein. In certain embodiments, the sustained release dosage form is formulated in a manner sufficient to form a matrix that includes the various components of the sustained release dosage form, such that when positioned in an oral cavity the matrix slowly dissolves and thereby lubricates the oral cavity and/or delivers a flavoring and/or beneficial agent thereto. Methods of formulating such dosage forms and administering them to an oral cavity for the treatment of an adverse condition are also provided.

US Patent:

54218365, Jun 6, 1995

Filed:

Nov 12, 1993

Appl. No.:

8/150871

Inventors:

Benjamin R. Ross - San Rafael CA

International Classification:

C10L 544

US Classification:

44560

Abstract:

A method of forming organic charcoal briquets from a mix of quantities of discrete coconut charcoal particles, borax, pulverized limestone, binder starch and water as well as the fuel product produced thereby.

US Patent:

20230132020, Apr 27, 2023

Filed:

Dec 23, 2022

Appl. No.:

18/088270

Inventors:

- Mountain View CA, US
Christa Wimberley - Mountain View CA, US
Benjamin Ross - New York NY, US
David Eisenberg - New York NY, US
Sudeep Gandhe - Sunnyvale CA, US
Kevin Chavez - Palo Alto CA, US
Raj Agarwal - Fremont CA, US

International Classification:

G06F 16/332
G06N 20/00
G06F 16/33
G10L 15/22
G06Q 10/10
G06F 16/00
G06F 40/30

Abstract:

Systems and methods provides for dialog management in real-time rather than turn taking. An example method included generating first candidate responses to triggering event. The triggering event may be receipt of a live stream chunk for the dialog or receipt of a backend response to a previous backend request for a dialog schema. The method also includes updating a list of candidate responses that are accepted or pending with at least on of the first candidate responses, and determining, for the triggering event, whether the list of candidate responses includes a candidate response that has a confidence score that meets a triggering threshold. The method also includes waiting for a next triggering event without providing a candidate response when the list does not include a candidate response that has a confidence score that meets the triggering threshold.

US Patent:

20210089565, Mar 25, 2021

Filed:

Dec 7, 2020

Appl. No.:

17/114350

Inventors:

- Mountain View CA, US
Christa Wimberley - Mountain View CA, US
Benjamin Ross - New York NY, US
David Eisenberg - New York NY, US
Sudeep Gandhe - Sunnyvale CA, US
Kevin Chavez - Palo Alto CA, US
Raj Agarwal - Fremont CA, US

International Classification:

G06F 16/332
G06N 20/00
G06F 16/33
G10L 15/22
G06Q 10/10
G06F 16/00
G06F 40/30

Abstract:

Systems and methods provides for dialog management in real-time rather than turn taking. An example method included generating first candidate responses to triggering event. The triggering event may be receipt of a live stream chunk for the dialog or receipt of a backend response to a previous backend request for a dialog shema. The method also includes updating a list of candidate responses that are accepted or pending with at least on of the first candidate responses, and determining, for the triggering event, whether the list of candidate responses includes a candidate response that has a confidence score that meets a triggering threshold. The method also includes waiting for a next triggering event without providing a candidate response when the list does not include a candidate response that has a confidence score that meets the triggering threshold.

US Patent:

20180232436, Aug 16, 2018

Filed:

Oct 13, 2017

Appl. No.:

15/783290

Inventors:

- Mountain View CA, US
Christa Wimberley - Mountain View CA, US
Benjamin Ross - New York NY, US
David Eisenberg - New York NY, US
Sudeep Gandhe - Sunnyvale CA, US
Kevin Chavez - Palo Alto CA, US
Raj Agarwal - Fremont CA, US

International Classification:

G06F 17/30
G06N 99/00
G06F 17/27

Abstract:

Systems and methods provide for dialog management in real-time rather than turn taking. An example method includes generating first candidate responses to a triggering event. The triggering event may be receipt of a live-stream chunk for the dialog or receipt of a backend response to a previous backend request for a dialog schema. The method also includes updating a list of candidate responses that are accepted or pending with at least one of the first candidate responses, and determining, for the triggering event, whether the list of candidate responses includes a candidate response that has a confidence score that meets a triggering threshold. The method also includes waiting for a next triggering event without providing a candidate response when the list does not include a candidate response that has a confidence score that meets the triggering threshold.