Bernard P Lassegue from 564 Emory Oaks Way, Decatur, GA 30033, age 65, Phone: 4043156037

Mitogenic Oxygenases
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US Patent:

7045351, May 16, 2006
Filed:

Dec 13, 2002
Appl. No.:

10/318906
Inventors:

J. David Lambeth - Decatur GA, US
Kathy K. Griendling - Stone Mountain GA, US
Bernard P. Lassegue - Decatur GA, US
Rebecca S. Arnold - Lilburn GA, US
Assignee:

Emory University - Atlanta GA
International Classification:

C12N 5/00
C12N 9/02
C12N 9/08
C12N 15/52
C07H 21/04
US Classification:

435325, 435189, 435192, 4352523, 4353201, 536 232
Abstract:

The present invention relates to new genes encoding for the production of novel proteins involved in generation of reactive oxygen intermediates that affect cell division. The present invention also provides vectors containing these genes, cells transfected with these vectors, antibodies raised against these novel proteins, kits for detection, localization and measurement of these genes and proteins, and methods to determine the activity of drugs to affect the activity of the proteins of the present invention.

Antibodies To Mitogenic Oxygenases
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US Patent:

7048923, May 23, 2006
Filed:

Dec 13, 2002
Appl. No.:

10/319236
Inventors:

J. David Lambeth - Decatur GA, US
Kathy K. Griendling - Stone Mountain GA, US
Bernard P. Lassegue - Decatur GA, US
Rebecca S. Arnold - Tucker GA, US
Guangjie Cheng - Atlanta GA, US
Assignee:

Emory University - Atlanta GA
International Classification:

A61K 39/395
A61K 39/40
C07K 16/00
US Classification:

4241331, 4241301, 5303881, 5303781, 5303888
Abstract:

The present invention relates to new genes encoding for the production of novel proteins involved in generation of reactive oxygen intermediates that affect cell division. The present invention also provides vectors containing these genes, cells transfected with these vectors, antibodies raised against these novel proteins, kits for detection, localization and measurement of these genes and proteins, and methods to determine the activity of drugs to affect the activity of the proteins of the present invention.

Dual Oxidases As Mitogenic And Endocrine Regulators
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US Patent:

7226769, Jun 5, 2007
Filed:

May 14, 2001
Appl. No.:

10/276153
Inventors:

J. David Lambeth - Decatur GA, US
Bernard P. Lassegue - Decatur GA, US
Kathy K. Griendling - Stone Mountain GA, US
Rebecca S. Arnold - Lilburn GA, US
Guangjie Cheng - Atlanta GA, US
Lisa Sharling - Scotland, GB
Guy Benian - Decatur GA, US
William A. Edens - Tucker GA, US
Assignee:

Emory University - Atlanta GA
International Classification:

C12N 9/08
C12N 9/00
C12N 9/02
C12P 21/06
C12Q 1/68
US Classification:

435192, 435 691, 435 6, 435183, 435189, 4353201, 4352523, 435325, 536 232
Abstract:

The present invention relates to new genes encoding for the production of novel proteins involved in generation of reactive oxygen intermediates and in peroxidative reactions that affect biological functions including cell division, thyroid hormone biosynthesis and tissue fibrosis. The present invention also provides vectors containing these genes, cells transfected with these vectors, antibodies raised against these novel proteins, kits for detection, localization and measurement of these genes and proteins, and methods to determine the activity of drugs to affect the activity of the proteins of the present invention.

Mitogenic Oxygenases
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US Patent:

7247709, Jul 24, 2007
Filed:

Mar 15, 2006
Appl. No.:

11/377884
Inventors:

J. David Lambeth - Atlanta GA, US
Kathy K. Griendling - Stone Mountain GA, US
Bernard P. Lassegue - Decatur GA, US
Rebecca S. Arnold - Tucker GA, US
Guangjie Cheng - Atlanta GA, US
Assignee:

Emory University - Atlanta GA
International Classification:

C07K 16/00
C12P 21/08
G01N 33/53
G01N 33/567
G01N 33/574
US Classification:

5303871, 5303879, 5303881, 5303891, 5303911, 5303913, 435 71, 435 72, 435 721, 435 723, 435 75
Abstract:

The present invention relates to new genes encoding for the production of novel proteins involved in generation of reactive oxygen intermediates that affect cell division. The present invention also provides vectors containing these genes, cells transfected with these vectors, antibodies raised against these novel proteins, kits for detection, localization and measurement of these genes and proteins, and methods to determine the activity of drugs to affect the activity of the proteins of the present invention.

Human Mitogenic Oxidase
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US Patent:

6620603, Sep 16, 2003
Filed:

Nov 10, 1999
Appl. No.:

09/437568
Inventors:

J. David Lambeth - Atlanta GA
Kathy K. Griendling - Stone Mountain GA
Bernard P. Lassegue - Decatur GA
Rebecca S. Arnold - Tucker GA
Guangjie Cheng - Atlanta GA
Assignee:

Emory University - Atlanta GA
International Classification:

C12N 902
US Classification:

435189, 435192, 436 232
Abstract:

The present invention relates to new genes encoding for the production of novel proteins involved in generation of reactive oxygen intermediates that affect cell division. The present invention also provides vectors containing these genes, cells transfected with these vectors, antibodies raised against these novel proteins, kits for detection, localization and measurement of these genes and proteins, and methods to determine the activity of drugs to affect the activity of the proteins of the present invention.