Richard C. Willson - Houston TX, US Ulrich Strych - Pearland TX, US Binh V. Vu - Houston TX, US
International Classification:
C12Q 1/70 C12Q 1/68
US Classification:
435 5, 435 611, 435 612
Abstract:
A methodology for bioassays and diagnostics in which a particulate label (ranging in size from nm-scale molecular assemblages to organisms on the scale of tens or hundreds of microns), such as, but not limited to, nanoparticles, bacteria, bacteriophage, Daphnia, and magnetic particles, serve carriers for analytes bound by molecular recognition elements such as antibodies, aptamers, etc. The described methodology is generally applicable to most pathogen assays and molecular diagnostics and also leads to enhanced sensitivity and convenience of use.
Systems And Methods For Detection Of Chemiluminescent Reactions
- Houston TX, US - Monterrey, MX Binh V. VU - Houston TX, US Olga Patricia VÁZQUEZ VILLEGAS - Monterrey, MX Federico Augusto RUIZ RUIZ - Monterrey, MX Marco Antonio RITO PALOMARES - Monterrey, MX
Assignee:
University of Houston System - Houston TX Instituto Tecnológico y de Estudios Superiores de Monterrey - Monterrey
Methods, devices and kit for analyzing a sample comprising 1,5-anhydroglucitol and a first analyte via one or more chemiluminescent reactions. Certain embodiments include measuring a first light response resulting from a first chemiluminescent reaction and measuring a second light response resulting from a second chemiluminescent reaction. Certain embodiments also include comparing the first light response to the second light response to determine a ratio of 1,5-anhydroglucitol and the first analyte.
- Houston TX, US Mary CRUM - Katy TX, US Dimple CHAVAN - Houston TX, US Ekaterini KOURENTZI - Bellaire TX, US Binh V. VU - Houston TX, US Richard C. WILLSON - Houston TX, US
Assignee:
The University of Houston System - Houston TX
International Classification:
G01N 33/542
Abstract:
Assay compositions and methods for detection of analytes that include covalent modification of assay elements, such that they are preserved, destroyed, created, or immobilized. Methods for detecting an analyte in a biological sample. The method includes providing a mixture of a biological sample potentially containing the analyte, and a molecular recognition element physically coupled to a covalent modification agent, wherein the molecular recognition element is capable of specific recognition of the analyte, and exposing the mixture to a first set of reaction conditions, wherein the analyte and molecular recognition element can associate to form a recognition complex. Upon formation of the recognition complex, the method further includes generating by use of the covalent modification agent, a template complex; and exposing the template complex to a second set of reaction conditions, wherein the template complex is amplified to generate a detectable product indicative of the presence of the analyte.
Systems And Methods For Detection Of Chemiluminescent Reactions
- Houston TX, US - Monterrey, MX Binh V. VU - Houston TX, US Olga Patricia VÁZQUEZ VILLEGAS - Monterrey, MX Federico Augusto RUIZ RUIZ - Monterrey, MX Marco Antonio RITO PALOMARES - Monterrey, MX
Assignee:
University of Houston System - Houston TX Tecnologico de Monterrey - Monterrey
Methods, devices and kit for analyzing a sample comprising 1,5-anhydroglucitol and a first analyte via one or more chemiluminescent reactions. Certain embodiments include measuring a first light response resulting from a first chemiluminescent reaction and measuring a second light response resulting from a second chemiluminescent reaction. Certain embodiments also include comparing the first light response to the second light response to determine a ratio of 1,5-anhydroglucitol and the first analyte.
Waterfield Energy
Director of Product Architecture
Waterfield Energy Dec 2013 - May 2014
Product Architect
Regardingit Feb 2013 - Sep 2013
Chief Technology Officer
Quorum Software Oct 2000 - Dec 2012
Senior Managing Technical Architect
Petrocosm Oct 1999 - Sep 2000
It Manager
Education:
University of Houston 1984 - 1989
Bachelors, Bachelor of Science, Computer Science
Skills:
Software Development Oracle Business Intelligence Sql Requirements Analysis It Strategy Integration Enterprise Architecture Microsoft Sql Server .Net Project Management Databases Soa Database Design Enterprise Software Pl/Sql Visual Studio Software Project Management C# Data Warehousing Agile Methodologies Crystal Reports Web Services Solution Architecture
Tillman Bauldwin, Anthony Hernandez, William Wychulis, Maureen Chaput, Nate Williams, Eric Hall, Nate Driml, Christopher Hegarty, Gregory Pedersen, Brian Leimbach, James Shehan