Boris M Tchernychev

from Chestnut Hill, MA

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Boris Tchernychev Phones & Addresses

  • 20 Payson Ave, Chestnut Hill, MA 02467 • 6175660761
  • West Roxbury, MA
  • 20 Payson Rd, Chestnut Hill, MA 02467 • 6175660761

Work

  • Company:
    Anchor therapeutics
    Jul 2010
  • Position:
    Principal scientist

Education

  • School / High School:
    The Weizmann Institute of Science
    1997
  • Specialities:
    Ph.D. in Biochemistry

Resumes

Boris Tchernychev Photo 1

Principal Scientist

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Location:
67 Rogers St, Cambridge, MA 02142
Industry:
Biotechnology
Work:
Anchor Therapeutics
Principal Scientist
Pfizer May 2005 - May 2008
Senior Scientist Ii
Tufts University May 2003 - May 2005
Research Associate
Beth Israel Deaconess Medical Center Jul 1997 - May 2003
Research Fellow
Education:
Weizmann Institute of Science 1992 - 1997
Doctorates, Doctor of Philosophy, Biology Moscow State University 1983 - 1988
Master of Science, Masters, Biology
Skills:
In Vivo Pharmacology
In Vivo Imaging
Cell Penetrating Peptides
Gpcr's Pharmacology
Adhesion Receptors
Inflammation
Metabolic Diseases
Stem Cells
Vascular Biology
Thrombosis and Hemostasis
Drug Discovery
In Vivo
High Throughput Screening
Antibodies
Cell
Peptides
Protein Chemistry
In Vitro
Vascular
Metabolism
Pharmacology
Elisa
Animal Models
Assay Development
Gpcrs
Cell Biology
Lead Change
Biomarkers
Flow Cytometry
Boris Tchernychev Photo 2

Principal Investigator

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Location:
Chestnut Hill, MA
Work:
Cyclerion
Principal Investigator
Education:
Weizmann Institute of Science 1992 - 1997
Doctorates, Doctor of Philosophy
Boris Tchernychev Photo 3

Boris Tchernychev Chestnut Hill, MA

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Work:
Anchor Therapeutics

Jul 2010 to 2000
Principal Scientist Anchor Therapeutics

Jan 2010 to Jul 2010
Senior Scientist Anchor Therapeutics

Jun 2008 to Jan 2010
Scientist II WYETH PHARMACEUTICALS

May 2005 to Jun 2008
Senior Research Scientist I Wyeth Research

2006 to 2007
Senior Research Scientist I TUFTS UNIVERSITY

Mar 2003 to Jun 2005
Research Associate BIDMC, HARVARD MEDICAL SCHOOL

Jul 1997 to May 2003
Post-Doctoral Fellow SHEMYAKIN INSTITUTE OF BIOORGANIC CHEMISTRY

Jun 1991 to Jun 1992
Research Fellow CENTER FOR MEDICAL BIOTECHNOLOGY, RUSSIA

Sep 1988 to Jun 1991
Research Fellow
Education:
The Weizmann Institute of Science
1997
Ph.D. in Biochemistry Moscow State University
1988
M.S. in Biophysics
Name / Title
Company / Classification
Phones & Addresses
Boris Tchernychev
Phd
Anchor Therapeutics
Biotechnology · Noncommercial Research Organization
67 Rogers St, Cambridge, MA 02142
1 Kendall Sq, Cambridge, MA 02139
6177151999, 6177157906

Us Patents

  • Cxcr4 Receptor Compounds

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  • US Patent:
    20130210709, Aug 15, 2013
  • Filed:
    Nov 4, 2009
  • Appl. No.:
    13/127443
  • Inventors:
    Thomas J. McMurry - Winchester MA, US
    Athan Kuliopulos - Winchester MA, US
    Lidija Covic - Boston MA, US
    Boris Tchernychev - Chestnut Hill MA, US
  • International Classification:
    C07K 7/08
    C07K 14/715
    C07K 7/06
  • US Classification:
    514 38, 530327, 530328, 530326, 514 215, 514 216, 514 214, 530324, 530325, 514 198, 514 193
  • Abstract:
    The invention relates generally to compounds which are allosteric modulators (e.g., positive and negative allosteric modulators, and allosteric agonists) of the G protein coupled receptor for stromal derived factor 1 (SDF-I), also known as the CX-CR4 receptor. The CXCR4 receptor compounds are derived from the intracellular loops and domains of the CXCR4 receptor. The invention also relates to the use of these CXCR4 receptor compounds and pharmaceutical compositions comprising the CXCR4 receptor compounds in the treatment of diseases and conditions associated with CXCR4 modulation such as bone marrow trans-plantation, chemosensitization, cancer, metastatic disease, inflammatory diseases, HIV infection and stem cell-based regenerative medicine.

  • Cxcr4 Receptor Compounds

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  • US Patent:
    20130005944, Jan 3, 2013
  • Filed:
    Feb 25, 2011
  • Appl. No.:
    13/580775
  • Inventors:
    Richard J. Looby - Reading MA, US
    Boris Tchernychev - Chestnut Hill MA, US
  • International Classification:
    C07K 7/08
    C07K 14/00
  • US Classification:
    530326, 530327
  • Abstract:
    The invention relates generally to compounds which are allosteric modulators {e.g., positive and negative allosteric modulators, and allosteric agonists) of the G protein coupled receptor for stromal derived factor 1 (SDF-I), also known as the CXCR4 receptor. The CXCR4 receptor compounds are derived from the intracellular loops and domains of the CXCR4 receptor. The invention also relates to the use of these CXCR4 receptor compounds and pharmaceutical compositions comprising the CXCR4 receptor compounds in the treatment of diseases and conditions associated with CXCR4 modulation such as bone marrow transplantation, chemosensitization, cancer, metastatic disease (e.g., cancer), auto-immune disease (e.g., rheumatoid arthritis), fibrosis disease (e.g., pulmonary), AIDS infection, cardiovascular disease, uveitis, inflammatory diseases, celiac disease HIV infection and stem cell-based regenerative medicine.
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