- Basel, CH - Lyon, FR Karen SEGAL - New York NY, US Ruby HOLDER - New York NY, US Sophie BOZEC - Antony, FR Sebastien BOLZE - Massieux, FR Pascale FOUQUERAY - Lyon, FR Christophe ARBET-ENGELS - Wellesley MA, US Julie DUBOURG - Lyon, FR Paul STRUMPH - Moneta VA, US Brandon Dale SWIFT - Apex NC, US Margaret Smith FLETCHER - San Clemente CA, US
International Classification:
A61K 31/53 A61P 3/10 A61P 13/12
Abstract:
The present disclosure is directed to a method of treating prediabetes or type 1 or type 2 diabetes mellitus comprising administering to a subject in need thereof an effective amount of imeglimin, wherein the subject has chronic kidney disease.
Antibiotic Conjugates Directly Linked With Steroid Drugs
- Irvine CA, US Ken Chow - Newport Coast CA, US LIMING WANG - Irvine CA, US MICHAEL E. GARST - Newport Beach CA, US MAYSSA ATTAR - Placentia CA, US BRANDON D. SWIFT - Camarillo CA, US
Assignee:
Allergan, Inc. - Irvine CA
International Classification:
A61K 47/48 A61K 9/00
US Classification:
514 23, 540110, 514176, 514175
Abstract:
The present invention describes novel single drug entities, formed by direct linkage of an antibiotic to a steroidal drug. Upon topical application to the eye, the conjugate would undergo enzymatic and/or hydrolytic cleavage to release the individual drugs. The antibiotic is coupled directly to the steroid drug.
- Irvine CA, US Ken Chow - Newport Coast CA, US LIMING WANG - Irvine CA, US MICHAEL E. GARST - Newport Beach CA, US MAYSSA ATTAR - Placentia CA, US BRANDON D. SWIFT - Camarillo CA, US
Assignee:
Allergan, Inc. - Irvine CA
International Classification:
A61K 47/48 A61K 9/00
US Classification:
514 205, 530321
Abstract:
The present invention describes Cyclosporine A/steroid hybrid analogs. These single drug entities are formed by connecting a steroid with Cyclosporine A. Upon topical application to the eye, the conjugate hybrid would undergo enzymatic and/or hydrolytic cleavage to release the individual drugs.
- Irvine CA, US Smita S. Bhat - Irvine CA, US Ken Chow - Newport Coast CA, US LIMING WANG - Irvine CA, US MICHAEL E. GARST - Newport Beach CA, US MAYSSA ATTAR - Placentia CA, US BRANDON D. SWIFT - Camarillo CA, US
The present invention describes antibiotic conjugates. These single drug entities are formed connecting one antibiotic with another antibiotic. Upon topical application to the eye, the conjugate hybrid would undergo enzymatic and/or hydrolytic cleavage to release the individual drugs.
- Irvine CA, US Smita S. Bhat - Irvine CA, US Ken Chow - Newport Coast CA, US LIMING WANG - Irvine CA, US MICHAEL E. GARST - Newport Beach CA, US MAYSSA ATTAR - Placentia CA, US BRANDON D. SWIFT - Camarillo CA, US
Assignee:
Allergan, Inc. - Irvine CA
International Classification:
A61K 47/48 A61K 9/00
US Classification:
514 26, 540110, 514176, 536 5, 540120, 514179
Abstract:
The present invention describes novel single drug entities, formed by the linkage of an antibiotic with a steroidal drug via a linker. Upon topical application to the eye, the conjugate would undergo enzymatic and/or hydrolytic cleavage to release the individual drugs.
Antibiotic Conjugates With Nonsteroidal Anti-Inflammatory Drugs
- Irvine CA, US Smita S. Bhat - Irvine CA, US Ken Chow - Newport Coast CA, US LIMING WANG - Irvine CA, US MICHAEL E. GARST - Newport Beach CA, US MAYSSA ATTAR - Placentia CA, US BRANDON D. SWIFT - Camarillo CA, US
The present invention describes single drug entities, formed by connecting an antibiotic moiety via a linker with a non-steroidal anti-inflammatory drug (NSAID) moiety. Upon topical application to the eye, the conjugate hybrid would undergo enzymatic and/or hydrolytic cleavage to release the individual antibiotic and NSAID drug.
- Irvine CA, US Ken Chow - Newport Coast CA, US LIMING WANG - Irvine CA, US MICHAEL E. GARST - Newport Beach CA, US MAYSSA ATTAR - Placentia CA, US BRANDON D. SWIFT - Irvine CA, US
Assignee:
Allergan, Inc. - Irvine CA
International Classification:
A61K 47/48 A61K 9/00
US Classification:
514175, 540110, 514176
Abstract:
The present invention describes steroid antibiotic conjugates. These single drug entities are formed connecting a steroid moiety and two same antibiotics moieties, or a steroid moiety and two different antibiotics moieties. Upon topical application to the eye, the conjugate hybrid would undergo enzymatic and/or hydrolytic cleavage to release the individual drugs.
- Irvine CA, US Ken Chow - Newport Coast CA, US LIMING WANG - Irvine CA, US MICHAEL E. GARST - Newport Beach CA, US MAYSSA ATTAR - Placentia CA, US BRANDON D. SWIFT - Camarillo CA, US
Assignee:
Allergan, Inc. - Irvine CA
International Classification:
A61K 47/48 A61K 9/00
US Classification:
514180, 540120, 514179
Abstract:
The present invention describes steroid conjugates. These single drug entities are formed by connecting two or more steroids via a linker. Upon topical application to the eye, the conjugate hybrid would undergo enzymatic and/or hydrolytic cleavage to release the individual steroid drugs.
Googleplus
Brandon Swift
Lived:
Salinas, Ca Hollister, Ca San Francisco, Ca Dublin, Ca Walnut Creek, CA Eureka, Ca Laguna Niguel, CA Lake Forest, Ca Westminster, Ca Long Beach, CA
Work:
Soledad High School - Science Teacher
About:
I'm an adventurous individual who loves the outdoors, loves photography, and loves his wife.
Brandon Swift (Thompson) 1997 graduate of El Toro High School in Lake forest, CA is on Memory Lane. Get caught up with Brandon and other high school alumni