Brian Craig Paul

US Patent:

6672502, Jan 6, 2004

Filed:

Nov 28, 2001

Appl. No.:

09/996621

Inventors:

Brian Kevin Paul - Corvallis OR
Richard Dean Wilson - Corvallis OR
David Eli Alman - Salem OR

Assignee:

The State of Oregon acting by and through the State Board of Higher Education on behalf of Oregon State University - Corvallis OR

International Classification:

B21D 3900

US Classification:

228164, 2281732, 228252, 228173, 29 174, 29904

Abstract:

A method and system for making a monolithic intermetallic structure are presented. The structure is made from lamina blanks which comprise multiple layers of metals which are patternable, or intermetallic lamina blanks that are patternable. Lamina blanks are patterned, stacked and registered, and processed to form a monolithic intermetallic structure. The advantages of a patterned monolithic intermetallic structure include physical characteristics such as melting temperature, thermal conductivity, and corrosion resistance. Applications are broad, and include among others, use as a microreactor, heat recycling device, and apparatus for producing superheated steam. Monolithic intermetallic structures may contain one or more catalysts within the internal features.

US Patent:

6793831, Sep 21, 2004

Filed:

Aug 5, 1999

Appl. No.:

09/369679

Inventors:

Brian Kevin Paul - Corvallis OR
Richard Budd Peterson - Corvallis OR
Tyson Jedd Terhaar - Tualatin OR

Assignee:

State of Oregon acting by and through the State Board of Higher Education on behalf of Oregon State University - Corvallis OR

International Classification:

C25F 700

US Classification:

216 36, 216 52, 156155, 156221, 156253, 1562744, 1563802, 156510, 29 171, 29 895, 148194, 148516, 148559, 148714, 228159, 228163

Abstract:

A method for fabricating devices in a pre-assembled state comprising forming plural laminae, registering the laminae, and bonding the laminae one to another is described. The plural laminae contain the substructures and structures of the device. The substructures are coupled to structures and other substructures by fixture bridges in the pre-assembled state. The substructures of the device are dissociated by eliminating the fixture bridges. The plural laminae are registered and bonded to form the device either before or after the fixture bridges are eliminated. The fixture bridges can be eliminated in a variety of ways, including vaporization by electrical current, chemical dissolution, or thermochemical dissociation. One method to selectively bond the laminae together is by microprojection welding. Microprojection welding comprises forming laminae with projections that extend from at least one planar surface of the lamina.

US Patent:

6913877, Jul 5, 2005

Filed:

Dec 17, 2001

Appl. No.:

10/024654

Inventors:

Frank W. R. Chaplen - Albany OR, US
William H. Gerwick - Corvallis OR, US
Goran Jovanovic - Corvallis OR, US
Wojtek Kolodziej - Corvallis OR, US
Jim Liburdy - Philomath OR, US
Phil McFadden - Corvallis OR, US
Brian Kevin Paul - Corvallis OR, US
Thomas K. Plant - Philomath OR, US
Janine E. Trempy - Corvallis OR, US
Corwin Willard - Monroe OR, US

Assignee:

State of Oregon acting by and through the State Board of Higher Education on behalf of Oregon State University - Corvallis OR

International Classification:

A61K035/60
A61K009/14
C12Q001/00
C12Q001/02

US Classification:

435 4, 435 405, 435 29, 424489, 424520

Abstract:

Methods of detecting bioactive compounds include exposing compounds to one or more classes of chromatophores and measuring or sensing associated changes in one or more of the chromatophores. Representative methods permit identification and quantification of neurotransmitters, toxins, hormones, and chemical warfare agents with or without prior knowledge of the content of a sample. In some examples, chromatophores based on Betta fish are used. Cytosensor apparatus using such chromatophores include means for exposing chromatophores to a sample and optical detection systems for assessing changes in chromatophore optical properties. Compounds can be identified or quantified based on a red-green-blue or hue saturation-value representations of transmitted or reflected light or based on other characterizations of transmitted or reflected light.

US Patent:

7507380, Mar 24, 2009

Filed:

Mar 21, 2005

Appl. No.:

11/086074

Inventors:

Chih-Hung Chang - Corvallis OR, US
Brian Kevin Paul - Corvallis OR, US
Vincent Thomas Remcho - Corvallis OR, US

Assignee:

State of Oregon Acting By and Through the State Board of Higher Education on behalf of Oregon State University - Corvallis OR

International Classification:

B01J 8/00
B01J 10/00
B32B 3/20
B32B 3/12

US Classification:

422129, 422198, 422130, 422139, 422141, 422142, 422145, 422146, 428188, 428166, 428172, 428178

Abstract:

Embodiments of an apparatus, system, and method for chemical synthesis and/or analysis are disclosed. One embodiment of a disclosed apparatus comprises a laminated, microfluidic structure defining a reactor and a separator. Such apparatuses, or portions thereof, generally have dimensions ranging from about 1 micrometer to about 100 micrometers. To implement synthetic processes, disclosed embodiments of the apparatus generally include at least one valve, and often plural, selectively actuatable valves. Detectors, including optical detectors, also can be used to detect product and other materials as they flow by, or are otherwise presented to, the detector. Individual apparatuses may be coupled both in series and in parallel to form a system for making chemical compounds. The apparatus is particularly useful for making compounds requiring iterative reaction schemes, and further can be used to make compounds having morphological structures that resemble the morphology of the apparatus itself, such as dendrimers.

US Patent:

7955504, Jun 7, 2011

Filed:

Oct 4, 2005

Appl. No.:

11/243937

Inventors:

Goran Jovanovic - Corvallis OR, US
Sundar V. Atre - Corvallis OR, US
Brian Kevin Paul - Corvallis OR, US
John Simonsen - Corvallis OR, US
Vincent Thomas Remcho - Corvallis OR, US
Chih-Hung Chang - Corvallis OR, US

Assignee:

State of Oregon acting by and through the State Board of Higher Education on behalf of Oregon State University - Corvallis OR

International Classification:

B01D 63/00
B01D 61/00
C02F 1/44

US Classification:

21032171, 210645, 21050029, 21050041

Abstract:

The present disclosure describes devices useful for microscale fluid purification, separation, and synthesis devices. Generally, such devices comprise a fluid membrane that separates two or more fluids flowing through plural microchannels operatively associated with the membrane. Often, the membrane is a semipermeable membrane, such as might be used with a filtration device, such as a dialyzer. Devices of the present invention can be combined with other microscale devices to make systems. For example, the devices may be coupled with one or more microchemical microfactories, one or more micromixers, one or more microheaters; etc. Particular materials had to be developed for use with certain embodiments of the device disclosed herein. For example, a new composite material was made comprising nanocrystalline cellulose filler and a polysulfone polymeric material. A dialyzer comprising the composite membrane also is disclosed.

US Patent:

8137554, Mar 20, 2012

Filed:

Apr 29, 2011

Appl. No.:

13/068037

Inventors:

Goran Jovanovic - Corvallis OR, US
Sundar V. Atre - Corvallis OR, US
Brian Kevin Paul - Corvallis OR, US
John Simonsen - Corvallis OR, US
Vincent Thomas Remcho - Corvallis OR, US
Chih-Hung Chang - Corvallis OR, US

Assignee:

State of Oregon acting by and through the State Board of Higher Education on behalf of Oregon State University - Corvallis OR

International Classification:

B01D 63/00
B01D 61/00
C02F 1/44

US Classification:

21032171, 210645, 21050029, 21050041

Abstract:

The present disclosure describes devices useful for microscale fluid purification, separation, and synthesis devices. Generally, such devices comprise a fluid membrane that separates two or more fluids flowing through plural microchannels operatively associated with the membrane. The fluids can both be liquids, gases, or a liquid and a gas, such as may be used for gas absorption into a liquid. Often, the membrane is a semipermeable membrane, such as might be used with a filtration device, such as a dialyzer. Devices of the present invention can be combined with other microscale devices to make systems. For example, the devices may be coupled with one or more microchemical microfactories, one or more micromixers, one or more microheaters; etc. Examples of devices made according to the present invention included an oxygenator, a dialzyer, microheat exchangers, etc. Particular materials had to be developed for use with certain embodiments of the device disclosed herein.

US Patent:

8273245, Sep 25, 2012

Filed:

Nov 9, 2011

Appl. No.:

13/292903

Inventors:

Goran Nadezda Jovanovic - Corvallis OR, US
Sundar V. Atre - New York NY, US
Brian Kevin Paul - Corvallis OR, US
Vincent Thomas Remcho - Corvallis OR, US
Chih-hung Chang - Corvallis OR, US

Assignee:

State of Oregon acting by and through the State Board of Higher Education on behalf of Oregon State University - Corvallis OR

International Classification:

B01D 63/00
B01D 61/00
C02F 1/44

US Classification:

21032171, 210645, 21050029, 21050041

Abstract:

The present disclosure describes devices useful for microscale fluid purification, separation, and synthesis. Such devices generally comprise a fluid membrane that separates two or more fluids flowing through plural microchannels operatively associated with the membrane. Often, the membrane is a semipermeable membrane, such as might be used with a filtration device, such as a dialyzer. Devices of the present invention can be combined with other microscale devices to make systems. For example, the devices may be coupled with one or more microchemical microfactories, one or more micromixers, one or more microheaters, etc. Examples of devices made according to the present invention included an oxygenator, a dialyzer, microheat exchangers, etc.

US Patent:

8414182, Apr 9, 2013

Filed:

Mar 30, 2009

Appl. No.:

12/414597

Inventors:

Brian Kevin Paul - Corvallis OR, US
Anna Evelyn Garrison - Philomath OR, US

Assignee:

State of Oregon acting by and through the State Board of Higher Education on behalf of Oregon State University - Corvallis OR

International Classification:

B01F 13/00

US Classification:

366341, 366336

Abstract:

A micromixer device has at least one fluid inlet channel and at least one fluid outlet channel. A plurality of pathways extend between the fluid inlet channel and the fluid outlet channel. The width of at least some of the plurality of pathways varies in a substantially parabolic manner along at least one dimension of the micromixer device.