Bruce M Howe

US Patent:

20130084326, Apr 4, 2013

Filed:

Oct 3, 2011

Appl. No.:

13/251860

Inventors:

Bruce Howe - Solana Beach CA, US
Brian Keller - Antioch CA, US

International Classification:

A61K 9/127
A61K 9/133
A61K 31/70
A61K 31/7088
A61K 38/02

US Classification:

424450, 514 44 R, 514 11, 514 23

Abstract:

The invention relates to liposomes having membranes composed of amphipathic molecules and long chain lipids in ratios that are proportionately higher in amphipathic molecules. Such ratios enhance the enzymatic breakdown of the inventive liposomes thereby improving the bioavailabity of encapsulated substances for oral delivery. Compositions of liposomes and methods of their use and manufacture are within the scope of the invention.

US Patent:

20130012599, Jan 10, 2013

Filed:

Aug 3, 2011

Appl. No.:

13/197709

Inventors:

LYNN HESSON - Neenak WI, US
Bruce Howe - Solana Beach CA, US
Vincent Duprat - Encinitas CA, US

International Classification:

A61K 47/36
A23L 1/302
A23L 1/27
A23L 1/304
A23P 1/08
A23L 1/30
A23L 1/305

US Classification:

514777, 426 89, 426 72, 426 99, 426103, 426 93, 426442, 426302, 426250

Abstract:

A surface treatment for the preparation of gasified consumable materials comprising active ingredients. The surface treatment may comprise a combination of flavors, sweeteners, and active ingredients such as nutritional supplements and/or pharmaceuticals. The invention avoids the degradation of active ingredients during the manufacturing process since the active ingredients are applied to the surface of the composition and not cooked with the gasified consumable material. Methods for making and using the disclosed compositions are also within the scope of the invention.

US Patent:

20190083514, Mar 21, 2019

Filed:

Nov 19, 2018

Appl. No.:

16/195214

Inventors:

Bruce L. HOWE - Solana Beach CA, US
Kodimule Shyam PRASAD - Bangalore, IN

International Classification:

A61K 31/593
A61K 9/00
A23L 33/155
A61K 36/81
A61K 47/44
A23K 20/158
A23K 20/174
A23D 9/007
A61K 31/592

Abstract:

The invention is directed to compositions of vitamin D having enhanced bioavailability and enhanced stability. Methods of making and using the compositions of the invention are contemplated and disclosed.

US Patent:

20170348209, Dec 7, 2017

Filed:

Jun 18, 2017

Appl. No.:

15/626152

Inventors:

Bruce L. Howe - San Diego CA, US
Kodimule Shyam Prasad - Bangalore, IN

International Classification:

A61K 8/34
A61K 8/55
A61K 8/92
A61Q 19/08
A61K 31/05
A61Q 19/02

Abstract:

Compositions of reserveratrol having enhanced properties. The compositions of the invention can comprise resveratrol and one or more agents that increase the bioavailability, efficacy and/or bioactivity of the resveratrol. Compositions of the invention find use in the treatment of a variety of conditions, including skin conditions and preventative health maintenance. Methods of making the inventive compositions are also contemplated.

US Patent:

20170202860, Jul 20, 2017

Filed:

Dec 28, 2016

Appl. No.:

15/392730

Inventors:

Bruce L. Howe - Solana Beach CA, US
Kodimule Prasad - Bangalore, IN

International Classification:

A61K 31/593
A61K 36/81
A23L 33/155
A61K 47/44

Abstract:

The invention is directed to compositions of vitamin D having enhanced bioavailability and enhanced stability. Methods of making and using the compositions of the invention are contemplated and disclosed.

US Patent:

20170072004, Mar 16, 2017

Filed:

Sep 10, 2015

Appl. No.:

14/850514

Inventors:

BRUCE HOWE - San Diego CA, US
KODIMULE PRASAD - Bangalore, IN

International Classification:

A61K 36/9066
A61K 47/44
A23L 33/10
A23L 33/115
A23L 29/25
A61K 31/12
A23L 33/105

Abstract:

Turmeric contains components such as curcuminoids which are beneficial to health and nutrition. Curcuminoids, including curcumin, are poorly absorbed by the body. The present invention provides compositions of curcuminoids having improved bioavailability. The present invention also provides methods of making such compositions and methods for their use in nutritional and therapeutic applications.

US Patent:

20160213584, Jul 28, 2016

Filed:

Jan 19, 2016

Appl. No.:

15/000943

Inventors:

BRUCE L. HOWE - San Diego CA, US
KODIMULE PRASAD - Bangalore, IN

International Classification:

A61K 8/34
A61Q 19/08
A61Q 19/02
A61K 8/55
A61K 8/92

Abstract:

Compositions of reserveratrol having enhanced properties. The compositions of the invention can comprise resveratrol and one or more agents that increase the bioavailability, efficacy and/or bioactivity of the resveratrol. Compositions of the invention find use in the treatment of a variety of conditions, including skin conditions and preventative health maintenance. Methods of making the inventive compositions are also contemplated.

US Patent:

20150223509, Aug 13, 2015

Filed:

Jan 4, 2015

Appl. No.:

14/588966

Inventors:

BRUCE L. HOWE - San Diego CA, US

International Classification:

A23L 2/39
A23L 2/12
A23L 2/10

Abstract:

Coconut water powder is highly hygroscopic and has a strong tendency to absorb ambient moisture. As coconut water powder absorbs water, it begins caking and ultimately forms a hard, solid mass that is difficult to use in the manufacture and formulation of coconut water-based beverages, drink mixes and foods. The present invention is based on the discovery that the addition of comestible oils, such as coconut oil, prior to dehydration of coconut water results in a coconut water powder with greatly reduced hyrgoscopy. Compositions comprising coconut water powder with reduced hygroscopy are the subject of the invention, as are methods of making and using such compositions.