Carl P Reppucci from 10 Sycamore Cir, Peabody, MA 01960, age 94, Phone: 9785353356

Resumes

Carl Reppucci

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Location:

14 Bucklin Rd, North Andover, MA 01845

Industry:

Financial Services

Work:

Bioconcept Laboratories
Product Development Scientist
Bentley Pharmaceuticals
Formulation Scientist and Research and Product Development
Arthur D. Little
Research Assistant
Stahl Finish
Chemist Technician
Macrochem
Research Associate

Education:

Bentley University 1971 - 1976
Merrimack College
Master of Science, Masters

Skills:

Writing
Supplies
Consulting
Clinical Trials
Chemical
Chemistry
In Vivo
Clinical Manufacturing
Vendors
Rescue
Iso
Us Army
Phase Ii
Particle Size
Cost
Transdermal
Coatings
Oversight
Ftir
Urethane
Nmr
Impurities
Road
On the Job Training
Particle
Scba
Rna
Batch Processing
Bench
Fire Management
Treatment
Tqm
Cmc
Hazardous Materials
Management
Dea
Ibm Rational Purify
Peptides
Wear
Patents
Bentley
Sop
Analyzer
Spray
Database Administration
Office Equipment
Organometallics
Respiration
Parenteral
Systems Engineering
Hplc
Gmp
Cpr Certified
Metals
Troubleshooting
System
Tests
Reports
Textiles
Fillers
Insulin
Microsoft Office
Drug Delivery
Variables
Testing
Microsoft Excel
Risk Management
Training
Creams
Polymers
Customer Service
Glass
Clean Rooms
Barrier
Peptidomimetics
Scheduling
Product Development
Quality Control
Research
Lotions
Icp Oes
Commercial Real Estate
R&D
Analysis
Binding
Hardness
Microscopy
Advertising Agency
Instron
Turbidity
Laboratory
.Net
Frequency
Uv
Gas Chromatography
Emulsions
Heavy Metals
Applications
Business Analysis
Home
Composites
Strategic Planning
Safety
Purification
Partial
Quality By Design
Leather
Filtration
Soil
Petroleum
Credit
Zeta Potential
Lacquer
Timelines
First Aid
Cvd
Spec
Mass Spec
Brookfield
Analytics
Cmo
Laptops
Technology Transfer
Uv/Vis
Msds
Dentistry
Therapists
Banking
International
Small Molecules
Army
Hazardous Waste Management
History
Logic Synthesis
Refractive Index
Start Ups
Decontamination
Differential Scanning Calorimetry
Electronics
Water Testing
Investments
Guidelines
Viscosity
Materials
Equities
Video
Green Chemistry
Frame
Preventive Maintenance
Throughput
Phase
Rheometry
Microsoft Word
Knowledge Base
Organic Chemistry
Polyurethane
Pharmaceutics
Manufacturing
In Vitro
Financial Analysis
Environmental Services
Aa
Skin
Budgets
Epa
Formulation
Optimization
Pharmaceutical Industry
Dna Extraction
Meetings
Icp
Fda
Environmental Analysis
Mercury
Strength Training

Product Development Chemist At Cpex Pharmaceuticals Inc. Formerly Bentley Pharmaceuticals Inc.

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Location:

Greater Boston Area

Industry:

Research

Experience:

Music (Self-employed) (Self-Employed; Music industry): Pianist, (1981-2010) MacroChem Corporation (Pharmaceuticals industry): Chemist/Research Associate, (1992-2002) Arthur D. Little (Privately Held; Management Consulting industry)...

Carl Reppucci

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Us Patents

Pharmaceutical Compositions And Methods For Peptide Treatment
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US Patent:

7244703, Jul 17, 2007
Filed:

Mar 5, 2004
Appl. No.:

10/895465
Inventors:

Robert J. Gyurik - Exeter NH, US
Carl Reppucci - North Andover MA, US
Assignee:

Bentley Pharmaceuticals, Inc. - Exeter NH
International Classification:

A61K 38/02
A61K 91/07
US Classification:

514 2, 514937
Abstract:

Compositions and methods for treating a patient with a pharmaceutically active peptide that combines a pharmaceutically active peptide, a permeation enhancer, and a carrier, are disclosed.

Pharmaceutical Compositions And Methods For Insulin Treatment
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US Patent:

7651996, Jan 26, 2010
Filed:

Aug 24, 2006
Appl. No.:

11/509417
Inventors:

Robert J. Gyurik - Exeter NH, US
Carl Reppucci - North Andover MA, US
Assignee:

CPEX Pharmaceuticals, Inc. - Exeter NH
International Classification:

A61K 38/28
A61K 51/00
A61M 36/14
US Classification:

514 3, 424 169, 514 4
Abstract:

Compositions and methods for treating a patient with insulin that combines insulin, a permeation enhancer, and a carrier that maintains an acidic pH, are disclosed.

Pharmaceutical Compositions And Methods For Peptide Treatment
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US Patent:

7816318, Oct 19, 2010
Filed:

Jun 7, 2007
Appl. No.:

11/811304
Inventors:

Robert J. Gyurik - Exeter NH, US
Carl Reppucci - North Andover MA, US
Assignee:

CPEX Pharmaceuticals, Inc. - Exeter NH
International Classification:

A61K 38/02
A61K 47/08
A61K 47/14
A61K 47/16
A61K 47/20
US Classification:

514 2, 514937
Abstract:

Disclosed are compositions and methods for treating a patient with a pharmaceutically active agent other than insulin selected from the group consisting of peptides, peptidomimetics, and proteins, wherein the pharmaceutical composition is in the form of an emulsified nasal spray comprising: a macrocyclic permeation enhancer, a liquid carrier comprising water, and a therapeutically effective amount of the pharmaceutically active agent; wherein the macrocyclic permeation enhancer is a Hsieh enhancer emulsified in the liquid carrier; and wherein the Hsieh enhancer has the following structure:.

Insulin Composition
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US Patent:

7989419, Aug 2, 2011
Filed:

Jun 8, 2007
Appl. No.:

11/811169
Inventors:

Robert J. Gyurik - Exeter NH, US
Carl Reppucci - North Andover MA, US
Assignee:

CPEX Pharmaceuticals, Inc. - Exeter NH
International Classification:

A61K 38/28
US Classification:

514 59
Abstract:

Pharmaceutical compositions for nasal administration to humans, or to warm-blooded animals, comprise: (A) a therapeutically effective amount of insulin; (B) a permeation enhancer; and (C) a liquid carrier; the compositions being further comprised of, or characterized by, any, or each, of: (D) a combination of non-ionic surfactants; wherein the combination of non-ionic surfactants comprises: (i) at least one fatty acid ester of a sugar or sugar alcohol and (ii) at least one pegylated fatty acid ester of a sugar or sugar alcohol; (E) an acidic pH, but no greater than a pH of 4. 5; and (F) an osmolality of

Pharmaceutical Compositions And Methods For Peptide Treatment
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US Patent:

8541359, Sep 24, 2013
Filed:

Sep 18, 2009
Appl. No.:

12/562974
Inventors:

Robert J. Gyurik - Exeter NH, US
Carl Reppucci - North Andover MA, US
Assignee:

CPEX Pharmaceuticals, Inc. - Exeter NH
International Classification:

A61K 9/107
A61K 38/02
US Classification:

514 11, 514937, 514938
Abstract:

Disclosed are compositions and methods for treating a patient with a pharmaceutically active agent other than insulin selected from the group consisting of peptides, peptidomimetics, and proteins, wherein the pharmaceutical composition is in the form of an emulsified nasal spray comprising: a macrocyclic permeation enhancer, a liquid carrier comprising water, and a therapeutically effective amount of a pharmaceutically active agent other than insulin selected from the group consisting of peptides, peptidomimetics, and proteins; wherein the macrocyclic permeation enhancer is a Hsieh enhancer emulsified in the liquid carrier.

Pharmaceutical Compositions And Methods For Insulin Treatment
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US Patent:

8044020, Oct 25, 2011
Filed:

Nov 6, 2009
Appl. No.:

12/614335
Inventors:

Robert J. Gyurik - Exeter NH, US
Carl Reppucci - North Andover MA, US
International Classification:

A61K 38/00
A61K 47/00
A61K 38/28
A61K 51/00
US Classification:

514 12, 514 11, 514 67, 514 68, 514 69, 424 169
Abstract:

Compositions and methods for treating a patient with insulin that combines insulin, a permeation enhancer, and a carrier that maintains an acidic pH, are disclosed.

Pharmaceutical Compositions And Methods For Insulin Treatment
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US Patent:

20050123592, Jun 9, 2005
Filed:

Dec 2, 2004
Appl. No.:

11/002858
Inventors:

Robert Gyurik - Exeter NH, US
Carl Reppucci - North Andover MA, US
International Classification:

A61K038/28
A61L015/16
US Classification:

424448000, 514003000
Abstract:

Compositions and methods for treating a patient with insulin that combines insulin, a permeation enhancer, and a carrier that maintains an acidic pH, are disclosed.

Fibrilliform-Free Insulin Composition
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US Patent:

20080045447, Feb 21, 2008
Filed:

Jun 8, 2007
Appl. No.:

11/811170
Inventors:

Robert Gyurik - Exeter NH, US
Carl Reppucci - North Andover MA, US
Zhengmao Li - Newmarket NH, US
International Classification:

A61K 38/28
A61M 11/00
A61P 3/08
US Classification:

514003000, 128200140
Abstract:

Compositions and methods are disclosed for treating a patient with insulin, wherein a composition in a form suitable for nasal delivery to a patient comprises a therapeutically effective amount of insulin, a permeation enhancer, a liquid carrier, and an acid present in said composition in an amount sufficient to provide an acidic pH, but not greater than a pH of 4.5, said acid being selected from the group consisting of: monovalent inorganic acid(s), sulfuric acid, and acetic acid. Preferably the composition is essentially-free of citrate(s) and essentially-free of phosphate(s). The composition being thus designed with the intent to provide a composition that is essentially-free of fibrilliform (or beta-sheet) insulin polymorphs.