Carole L Cramer

age ~72

from State University, AR

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Also known as:

Carole Lyn Cramer
Carol E Cramer
Carole Radin
Carol L Camer
Harsha Tatikonda

Connected to:

Carole Cramer Phones & Addresses

State University, AR
Longboat Key, FL
Tahoe City, CA
Jonesboro, AR
Richmond, KY
Blacksburg, VA
Salem, OR
Parker, CO
Murrieta, CA
Oceanside, CA

Resumes

Chief Executive Officer

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Industry:

Marketing And Advertising

Work:

Elegante Por Tu
Chief Executive Officer

Chief Scientific Officer

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Location:

P/O Box 2605, State University, AR

Industry:

Biotechnology

Work:

Arkansas Center For Plant-Powered Production 2007 - 2015
Director
Biostrategies Lc 2007 - 2015
Chief Scientific Officer
Arkansas State University 2007 - 2015
Professor, Arkansas Biosciences Institute
Croptech Corp 1992 - 2003
Cso, Co-Founder

Education:

Salk Institute 1982 - 1986
Uc Irvine 1976 - 1982
Doctorates, Doctor of Philosophy, Molecular Biology, Biochemistry University of California, Berkeley 1970 - 1974
Bachelors, Bachelor of Science

Skills:

Biotechnology
Cell Biology
Immunology
Bioinformatics
Microscopy
Start Ups
Molecular Biology
Biochemistry
Research
Cell Culture

Carole Cramer

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Us Patents

Plant-Based Expression Of Avian Interleukin-12 And Methods Of Producing And Using Same
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US Patent:

8431774, Apr 30, 2013
Filed:

Oct 6, 2009
Appl. No.:

12/574598
Inventors:

Carole L. Cramer - Jonesboro AR, US
Maureen C. Dolan - Jonesboro AR, US
Giuliana Medrano - Jonesboro AR, US
David N. Radin - Jonesboro AR, US
Assignee:

University of Arkansas-Jonesboro - State University AR
International Classification:

A01H 5/00
C07K 14/54
C12N 15/24
C12N 5/04
US Classification:

800288, 530351, 800295, 800298, 800278, 536 231, 536 235
Abstract:

The invention is a plant-based production of biologically active avian interleukin-12 protein and functional units for increasing the protective and/or immunological response in an animal, for use as an adjuvant with a vaccine to control avian infectious diseases, and methods of producing and using the same. Specifically, avian interleukin-12 was produced from a plant-based expression system and demonstrated that it stimulates production of immune responses in birds.

Methods Of Delivery Of Molecules To Cells Using A Ricin Subunit And Compositions Relating To Same
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US Patent:

20100240597, Sep 23, 2010
Filed:

Jun 12, 2008
Appl. No.:

12/664342
Inventors:

Carole L. Cramer - Jonesboro AR, US
Maureen C. Dolan - Jonesboro AR, US
Michael J. Reidy - Rockville MD, US
Assignee:

ARKANSAS STATE UNIVERSITY - State University AR
International Classification:

A61K 38/12
C07K 14/415
C12P 21/06
C12N 5/02
C12N 5/10
US Classification:

514 212, 530370, 435 701, 435375, 435419
Abstract:

A method of preparing molecules of interest for delivery to eukaryotic cells is shown, wherein a ricin B chain subunit not having a ribosome inactivating subunit and retaining lectin activity is modified by modifying the first cysteine residue to be absent or substituted with an amino acid other than cysteine, or removing a protease sensitive site at the N-terminal of the subunit, or adding an endoplasmic reticulum retrieval signal, and operatively associating the subunit with a molecule of interest. Methods of operatively associating the subunit and molecule of interest include chemical conjugation at primary amines, conjugation with N-glycans of the subunit, a disulfide bond, and assembly of immunoglobulin domains. The invention provides for operatively associating multiple molecules of interest with a ricin B chain subunit, and delivery into targeted cells, cell components, and combination of cells.