Casey L Miller

US Patent:

20210298824, Sep 30, 2021

Filed:

Jun 11, 2021

Appl. No.:

17/304007

Inventors:

Pajhand IRANITALAB - San Ramon CA, US
Casey Andrew MILLER - Campbell CA, US
Thomas Ryan McGRATH - Santa Clara CA, US
Manuel Arzadon JAVIER - Santa Clara CA, US
Anisha BAPNA - Edison NJ, US
Zoar Jacob ENGELMAN - New York NY, US
Howard LEVIN - Teaneck NJ, US
Nicholas C. VanDILLEN - Lenexa KS, US
Anne Marie AHONEN - Lenexa KS, US

International Classification:

A61B 18/14

Abstract:

Systems, devices, and methods for transvascular ablation of target tissue. The devices and methods may, in some examples, be used for splanchnic nerve ablation to increase splanchnic venous blood capacitance to treat at least one of heart failure and hypertension. For example, the devices disclosed herein may be advanced endovascularly to a target vessel in the region of a thoracic splanchnic nerve (TSN), such as a greater splanchnic nerve (GSN) or a TSN nerve root. Also disclosed are methods of treating heart failure, such as HFpEF, by endovascularly ablating a thoracic splanchnic nerve to increase venous capacitance and reduce pulmonary blood pressure.

US Patent:

20210220043, Jul 22, 2021

Filed:

Jan 19, 2021

Appl. No.:

17/152665

Inventors:

Pajhand IRANITALAB - San Ramon CA, US
Casey Andrew MILLER - Campbell CA, US
Thomas Ryan McGRATH - Santa Clara CA, US
Anisha BAPNA - Edison NJ, US
Zoar Jacob ENGELMAN - New York NY, US
Howard LEVIN - Teaneck NJ, US
Nicholas C. VanDILLEN - Lenexa KS, US
Anne Marie AHONEN - Lenexa KS, US

International Classification:

A61B 18/14

Abstract:

Systems, devices, and methods for transvascular ablation of target tissue. The devices and methods may, in some examples, be used for splanchnic nerve ablation to increase splanchnic venous blood capacitance to treat at least one of heart failure and hypertension. For example, the devices disclosed herein may be advanced endovascularly to a target vessel in the region of a thoracic splanchnic nerve (TSN), such as a greater splanchnic nerve (GSN) or a TSN nerve root. Also disclosed are methods of treating heart failure, such as HFpEF, by endovascularly ablating a thoracic splanchnic nerve to increase venous capacitance and reduce pulmonary blood pressure.