Catherine J Greer

US Patent:

54478391, Sep 5, 1995

Filed:

Apr 20, 1993

Appl. No.:

8/050743

Inventors:

M. Michele Manos - Richmond CA
Heidi M. Bauer - Oakland CA
Catherine E. Greer - Oakland CA
Robert M. Resnick - Richmond CA
Yi Ting - Berkeley CA

Assignee:

Hoffmann-La Roche Inc. - Nutley NJ

International Classification:

C12Q 168
C07H 2104

US Classification:

435 5

Abstract:

The presence of human papillomavirus (HPV) in a sample can be detected and the HPV typed by a method that involves the amplification of HPV DNA sequences by the polymerase chain reaction (PCR). The primers used in the method are consensus primers that can be used to amplify a particular region of the genome of any HPV. The presence of HPV in a sample is indicated by the formation of amplified DNA. The HPV nucleic acid is detected by consensus probes that may be short oligonucleotide probes or long genetic probes. The HPV is typed by the use of type-specific DNA probes specific for the amplified region of DNA.

US Patent:

57056277, Jan 6, 1998

Filed:

May 26, 1995

Appl. No.:

8/452055

Inventors:

M. Michele Manos - Richmond CA
Heidi M. Bauer - Oakland CA
Catherine E. Greer - Oakland CA
Robert M. Resnick - Richmond CA
Yi Ting - Berkeley CA

Assignee:

Roche Molecular Systems, Inc. - Branchburg NJ

International Classification:

C07H 2104
C07H 2102
C12Q 170
C12Q 168

US Classification:

536 243

Abstract:

The presence of human papillomavirus (HPV) in a sample can be detected and the HPV typed by a method that involves the amplification of HPV DNA sequences by the polymerase chain reaction (PCR). The primers used in the method are consensus primers that can be used to amplify a particular region of the genome of any HPV. The presence of HPV in a sample is indicated by the formation of amplified DNA. The HPV nucleic acid is detected by consensus probes that may be short oligonucleotide probes or long generic probes. The HPV is typed by the use of type-specific DNA probes specific for the amplified region of DNA.