Catherine A Mccall

US Patent:

6410714, Jun 25, 2002

Filed:

Mar 24, 2000

Appl. No.:

09/535521

Inventors:

Eric R. Weber - Fort Collins CO
Catherine A. McCall - Boulder CO

Assignee:

Heska Corporation - Fort Collins CO

International Classification:

C07H 2104

US Classification:

536 235, 536 231, 435 691, 435455, 435471, 4352351, 4352523, 4353201

Abstract:

The present invention relates to canine low affinity IgE receptor (CD23) nucleic acid molecules, proteins encoded by such nucleic acid molecules, antibodies raised against such proteins, compounds capable of regulating, e. g. , inhibiting or activating, the function of such proteins, and methods to identify such regulatory compounds. The present invention also includes therapeutic compositions comprising such nucleic acid molecules, proteins, antibodies, or regulatory compounds, methods to use such therapeutic compositions, and methods and kits to detect CD23 proteins.

US Patent:

6455686, Sep 24, 2002

Filed:

Apr 15, 1999

Appl. No.:

09/292225

Inventors:

Catherine A. McCall - Boulder CO
Shirley Wu Hunter - Fort Collins CO
Eric R. Weber - Fort Collins CO

Assignee:

Heska Corporation - Fort Collins CO

International Classification:

C07H 2102

US Classification:

536 234, 36 231, 36 2432

Abstract:

The present invention relates to high molecular weight Dermatophagoides proteins, nucleic acid molecules encoding such proteins, and therapeutic and diagnostic reagents derived from such proteins.

US Patent:

6573372, Jun 3, 2003

Filed:

Jan 7, 2000

Appl. No.:

09/479614

Inventors:

Catherine McCall - Boulder CO
Eric Weber - Fort Collins CO

Assignee:

Heska Corporation - Fort Collins CO

International Classification:

C07H 2104

US Classification:

536 2353, 536 231, 536 235, 514 44

Abstract:

The invention relates to: nucleic acid molecules encoding the light chain and heavy chain of feline immunoglobulin E (IgE), including species-specific regions of feline IgE; proteins encoded by the nucleic acid molecules; inhibitors to the nucleic acids and proteins; antibodies to the proteins; cells transformed with the nucleic acid molecules; assays employing the transformed cells, nucleic acids, antibodies and/or proteins or portions thereof; methods for treating IgE-mediated responses (ie. allergy) using the materials provided; methods for eliciting an immune response to IgE and kits containing the nucleic acid molecules, proteins or derivatives thereof (ie. antibodies).

US Patent:

6582701, Jun 24, 2003

Filed:

Feb 29, 2000

Appl. No.:

09/515311

Inventors:

Eric R. Weber - Fort Collins CO
Catherine A. McCall - Boulder CO

Assignee:

Heska Corporation - Fort Collins CO

International Classification:

A61K 3900

US Classification:

4241851, 530350

Abstract:

The present invention relates to equine Fc epsilon receptor alpha chain nucleic acid molecules, proteins encoded by such nucleic acid molecules, antibodies raised against such proteins, and inhibitors of such proteins. The present invention also includes methods to detect IgE using such proteins and antibodies. Also included in the present invention are therapeutic compositions comprising such proteins, nucleic acid molecules, antibodies and/or inhibitory compounds as well as the use of such therapeutic compositions to mediate Fc epsilon receptor-mediated biological responses.

US Patent:

6703360, Mar 9, 2004

Filed:

Apr 9, 2001

Appl. No.:

09/828995

Inventors:

Catherine A. McCall - Boulder CO
Liang Tang - Fort Collins CO

Assignee:

Heska Corporation - Fort Collins CO

International Classification:

C07K 14705

US Classification:

514 2, 4241921, 536 235, 530350, 530351, 5303873, 435 691, 435 697, 4353201

Abstract:

The invention relates to canine immunoglobulin G (IgG) and canine interleukin-13 receptors (IL-13R) as well as fusion proteins containing canine IgG and/or canine IL-13R. In particular, the present invention discloses nucleic acid molecules encoding canine IgG, including species-specific regions of the heavy chain of canine IgG, and canine IL-13R alpha chain (IL-13R) proteins, particularly canine interleuken receptor alpha 1 (IL-13R1) and canine interleuken receptor alpha 2 (IL-13R2) proteins. Also included are canine IgG and IL-13R proteins, antibodies having selectivity for such proteins, inhibitors of such proteins and/or nucleic acid molecules, cells transformed with said nucleic acid molecules, assays employing such cells, nucleic acids molecules, proteins, antibodies and/or inhibitors, and therapeutic compositions comprising said nucleic acids molecules, proteins, antibodies and/or inhibitors. Also included are kits containing said molecules or chimera thereof, including their use to evaluate and regulate an immune response in an animal.

US Patent:

6887672, May 3, 2005

Filed:

May 8, 2003

Appl. No.:

10/434817

Inventors:

Eric R. Weber - Fort Collins CO, US
Catherine A. McCall - Boulder CO, US

Assignee:

Heska Corporation - Fort Collins CO

International Classification:

G01N033/53
G01N033/536
G01N033/537
C07K014/705

US Classification:

435 71, 435 75, 435 77, 435 78, 435 792, 436501, 436507, 436513, 436526, 436527, 436530, 436533, 436534, 436536, 436539, 436542, 436546, 530395

Abstract:

The present invention relates to equine Fc epsilon receptor alpha chain nucleic acid molecules, proteins encoded by such nucleic acid molecules, antibodies raised against such proteins, and inhibitors of such proteins. The present invention also includes methods to detect IgE using such proteins and antibodies. Also included in the present invention are therapeutic compositions comprising such proteins, nucleic acid molecules, antibodies and/or inhibitory compounds as well as the use of such therapeutic compositions to mediate Fc epsilon receptor-mediated biological responses.

US Patent:

7128921, Oct 31, 2006

Filed:

Sep 14, 2000

Appl. No.:

09/662293

Inventors:

Catherine A. McCall - Boulder CO, US
Shirley Wu Hunter - Fort Collins CO, US
Eric R. Weber - Fort Collins CO, US

Assignee:

Heska Corporation - Loveland CO

International Classification:

A61K 39/395

US Classification:

4242751, 530324, 530326, 530857, 435275

Abstract:

The present invention relates to high molecular weight proteins, nucleic acid molecules encoding such proteins, and therapeutic and diagnostic reagents derived from such proteins.

US Patent:

7183080, Feb 27, 2007

Filed:

Feb 24, 2004

Appl. No.:

10/787382

Inventors:

Shumin Yang - Palo Alto CA, US
Catherine A. McCall - Boulder CO, US
Eric R. Weber - Fort Collins CO, US

Assignee:

Heska Corporation - Loveland CO

International Classification:

C12P 21/06
C07H 21/02
C07H 21/04
C12N 5/00
C12N 15/00
C12N 15/63

US Classification:

435 691, 4353201, 435325, 435455, 536 231, 536 235

Abstract:

The present invention relates to canine interleukin-5 proteins; canine interleukin-5 nucleic acid molecules, including those that encode canine interleukin-5 proteins; to antibodies raised against such proteins; and to inhibitory compounds that regulate such proteins. The present invention also includes methods to identify and obtain such proteins, nucleic acid molecules, antibodies, and inhibitory compounds. Also included in the present invention are therapeutic compositions comprising such proteins, nucleic acid molecules, antibodies and/or inhibitory compounds as well as the use of such therapeutic compositions to regulate an immune response in an animal.