Catherine M Park

US Patent:

8246952, Aug 21, 2012

Filed:

Oct 7, 2009

Appl. No.:

12/575411

Inventors:

Catherine Park - San Francisco CA, US
Mina J. Bissell - Berkeley CA, US

Assignee:

The Regents of the University of California - Oakland CA

International Classification:

A61K 39/395

US Classification:

4241301

Abstract:

A method for increasing or monitoring apoptosis in tumor cells by the co-administration of ionizing radiation and an anti-integrin antibody. Increasing apoptosis reduces tumor growth in vivo and in a cell culture model. The antibody is directed against the beta-1 integrin subunit and is inhibitory of beta-1 integrin signaling. Other molecules having an inhibitory effect on beta-1 integrin, either in signaling or in binding to its cognate extracellular receptors may also be used. The present method is particularly of interest in treatment of tumor cells associated with breast cancer, wherein radiation is currently used alone. The present method further contemplates a monoclonal antibody suitable for human administration that may further comprise a radioisotope attached thereto.

US Patent:

20070237711, Oct 11, 2007

Filed:

Jun 2, 2005

Appl. No.:

11/628476

Inventors:

Catherine Park - San Francisco CA, US
Mina Bissell - Berkeley CA, US

International Classification:

A61K 51/00
C07K 16/00
C07K 2/00
C12N 5/02

US Classification:

424001490, 435375000, 530300000, 530391300

Abstract:

A method for increasing or monitoring apoptosis in tumor cells by the co-administration of ionizing radiation and an anti-integrin antibody. Increasing apoptosis reduces tumor growth in vivo and in a cell culture model. The antibody is directed against the beta-1 integrin subunit and is inhibitory of beta-1 integrin signaling. Other molecules having an inhibitory effect on beta-1 integrin, either in signaling or in binding to its cognate extracellular receptors may also be used. The present method is particularly of interest in treatment of tumor cells associated with breast cancer, wherein radiation is currently used alone. The present method further contemplates a monoclonal antibody suitable for human administration that may further comprise a radioisotope attached thereto.

US Patent:

20200383576, Dec 10, 2020

Filed:

Apr 21, 2020

Appl. No.:

16/854463

Inventors:

- Oakland CA, US
Catherine Park - San Francisco CA, US
Bernard Boser - Berkeley CA, US

International Classification:

A61B 5/00
A61K 49/00

Abstract:

The disclosed apparatus, systems and methods relate to devices, systems and methods for intra-operative imaging.

US Patent:

20190000320, Jan 3, 2019

Filed:

Aug 25, 2017

Appl. No.:

15/687205

Inventors:

- San Francisco CA, US
Catherine Park - San Francisco CA, US
Bernard Boser - Berkeley CA, US

International Classification:

A61B 5/00
A61K 49/00

Abstract:

The disclosed apparatus, systems and methods relate to devices, systems and methods for intraoperative imaging.

US Patent:

20180153407, Jun 7, 2018

Filed:

Nov 21, 2017

Appl. No.:

15/820386

Inventors:

- Oakland CA, US
Catherine Park - San Francisco CA, US
Bernard Boser - Berkeley CA, US

International Classification:

A61B 5/00
A61K 49/00

Abstract:

The disclosed apparatus, systems and methods relate to interventional magnetic resonance imaging (iMRI). More specifically, clinical applications of the disclosed include magnetic resonance (MR) guided procedures such as endovascular interventions, percutaneous biopsies or deep brain stimulation

US Patent:

20160374559, Dec 29, 2016

Filed:

Mar 18, 2016

Appl. No.:

15/074614

Inventors:

- Oakland CA, US
Catherine Park - San Francisco CA, US
Bernard Boser - Berkeley CA, US

International Classification:

A61B 5/00
A61K 49/00

Abstract:

An imager for in vivo viewing of diseased tissue by way of fluorescently conjugated molecules. A generally planar imaging surface with a microlens array. The imager may be modular, such that a plurality of generally planar imaging surfaces can be used to image various aspects of disease tissue simultaneously. Certain implementations include an angle-selective imager, wherein light from substantially perpendicular to the plane of the imager is received, while incident light is selectively eliminated.

Address:

52 Monte Vis Ave, Atherton, CA 94027

Phone:

6503546522

VIN:

4JGBB8GB6BA650694

Make:

MERCEDES-BENZ

Model:

M-CLASS

Year:

2011