Catherine A Phillips

US Patent:

7282222, Oct 16, 2007

Filed:

Mar 14, 2003

Appl. No.:

10/388964

Inventors:

Catherine Phillips - Amarillo TX, US

Assignee:

The United States of America as Represented by the Department of Veterans Affairs - Washington DC

International Classification:

A61K 35/28
A61K 35/26
A01N 25/00

US Classification:

424577, 514885

Abstract:

The present invention is directed to methods for delivering cells to a target tissue in a mammal using glycoconjugate to traffic the cell to a desired organ in the mammal. The methods according to the present invention are especially applicable to administering stem cells such as those derived from the bone marrow or from umbilical cord tissue. The methods are also useful for targeting a gene of interest to a tissue in a mammal by introducing a cell containing the gene of interest and administering a glycoconjugate to the mammal.

US Patent:

7563459, Jul 21, 2009

Filed:

Apr 20, 2007

Appl. No.:

11/788643

Inventors:

Catherine A. Phillips - Amarillo TX, US

Assignee:

The United States of America as represented by the Department of Vetrans Affairs - Washington DC

International Classification:

A61K 35/28
A61K 35/26
A01N 25/00

US Classification:

424577, 514885

Abstract:

The present invention is directed to methods for delivering cells to a target tissue in a mammal using glycoconjugate to traffic the cell to a desired organ in the mammal. The methods according to the present invention are especially applicable to administering stem cells such as those derived from the bone marrow or from umbilical cord tissue. The methods are also useful for targeting a gene of interest to a tissue in a mammal by introducing a cell containing the gene of interest and administering a glycoconjugate to the mammal.

US Patent:

20060171934, Aug 3, 2006

Filed:

Feb 1, 2005

Appl. No.:

10/940691

Inventors:

Catherine Phillips - Amarillo TX, US

Assignee:

Department of Veterans Affairs, Rehabilitation R&D Service - Baltimore MD

International Classification:

A61K 38/17
A61K 48/00
A61K 35/14

US Classification:

424093210, 424093700, 514008000

Abstract:

The present invention is directed to methods for delivering cells to a target tissue in a mammal using glycoconjugate to traffic the cell to a desired organ in the mammal. The methods according to the present invention are especially applicable to administering lymphoid cells such as natural killer (NK) cells activated with interleukin-2 (IL-2), lymphokine-activated killer (LAK) cells and/or tumor-infiltrating lymphocytes (TILs) and/or cytotoxic lymphocytes (CTLs), or stem cells such as those derived from the bone marrow or from umbilical cord tissue. The methods are also useful for targeting a gene of interest to a tissue in a mammal by introducing a cell containing the gene of interest and administering a glycoconjugate to the mammal.

US Patent:

20070196331, Aug 23, 2007

Filed:

Apr 20, 2007

Appl. No.:

11/788636

Inventors:

Catherine Phillips - Amarillo TX, US
Julian Breillatt - , US

International Classification:

A61K 38/19

US Classification:

424085100, 514008000

Abstract:

The present invention is directed to methods for delivering cells to a target tissue in a mammal using glycoconjugate to traffic the cell to a desired organ in the mammal. The methods according to the present invention are especially applicable to administering stem cells such as those derived from the bone marrow or from umbilical cord tissue. The methods are also useful for targeting a gene of interest to a tissue in a mammal by introducing a cell containing the gene of interest and administering a glycoconjugate to the mammal.

US Patent:

20070243173, Oct 18, 2007

Filed:

Apr 20, 2007

Appl. No.:

11/788577

Inventors:

Catherine Phillips - Amarillo TX, US

International Classification:

A61K 35/28

US Classification:

424093700

Abstract:

The present invention is directed to methods for delivering cells to a target tissue in a mammal using glycoconjugate to traffic the cell to a desired organ in the mammal. The methods according to the present invention are especially applicable to administering stem cells such as those derived from the bone marrow or from umbilical cord tissue. The methods are also useful for targeting a gene of interest to a tissue in a mammal by introducing a cell containing the gene of interest and administering a glycoconjugate to the mammal.

US Patent:

20070243174, Oct 18, 2007

Filed:

Apr 20, 2007

Appl. No.:

11/788578

Inventors:

Catherine Phillips - Amarillo TX, US
Julian Breillatt - , US

International Classification:

A61K 35/28

US Classification:

424093700

Abstract:

The present invention is directed to methods for delivering cells to a target tissue in a mammal using glycoconjugate to traffic the cell to a desired organ in the mammal. The methods according to the present invention are especially applicable to administering stem cells such as those derived from the bone marrow or from umbilical cord tissue. The methods are also useful for targeting a gene of interest to a tissue in a mammal by introducing a cell containing the gene of interest and administering a glycoconjugate to the mammal.

US Patent:

20070248577, Oct 25, 2007

Filed:

Apr 20, 2007

Appl. No.:

11/788645

Inventors:

Catherine Phillips - Amarillo TX, US
Julian Breillatt - , US

International Classification:

A61K 45/00
A61K 31/739
A61K 38/17

US Classification:

424093700, 514054000, 514008000

Abstract:

The present invention is directed to methods for delivering cells to a target tissue in a mammal using glycoconjugate to traffic the cell to a desired organ in the mammal. The methods according to the present invention are especially applicable to administering stem cells such as those derived from the bone marrow or from umbilical cord tissue. The methods are also useful for targeting a gene of interest to a tissue in a mammal by introducing a cell containing the gene of interest and administering a glycoconjugate to the mammal.

US Patent:

20100047215, Feb 25, 2010

Filed:

Oct 30, 2009

Appl. No.:

12/610183

Inventors:

Catherine A. PHILLIPS - Amarillo TX, US

International Classification:

A61K 35/12

US Classification:

424 937

Abstract:

The present invention is directed to methods for delivering stem cells to a target tissue in a mammal using glycoconjugate to traffic the stem cells to a desired organ in the mammal. The methods according to the present invention are especially applicable to administering stem cells such as those derived from the bone marrow or from umbilical cord tissue. The methods are also useful for targeting a gene of interest to a tissue in a mammal by introducing a cell containing the gene of interest and administering a glycoconjugate to the mammal.