The University of Alabama at Birmingham
Professor
The University of Alabama at Birmingham Oct 2007 - Sep 2011
Associate Professor
The University of Alabama at Birmingham Nov 1996 - Sep 2007
Assistant Professor
Loyola University Medical Center Oct 1989 - Sep 1994
Postdoctoral Fellow
Education:
Southern Illinois University School of Medicine 1984 - 1989
Doctorates, Doctor of Philosophy, Microbiology, Philosophy, Immunology
Idaho State University College of Business 1982 - 1984
Master of Science, Masters, Microbiology
Madras Christian College 1977 - 1980
Bachelors, Bachelor of Science, Zoology
Rishi Valley School 1971 - 1976
Skills:
Molecular Biology Immunology Cell Biology Cell Culture Lifesciences Science Life Sciences Biochemistry Animal Models Western Blotting Research Pcr Flow Cytometry Cell Neuroscience Protein Chemistry Cancer
Us Patents
Markers For Determination Of Patient Responsiveness
Robert C. Axtell - Menlo Park CA, US Lawrence Steinman - Stanford CA, US May H. Han - Menlo Park CA, US Brigit A. de Jong - Nijmegen, NL Chander Raman - Birmingham AL, US Michael Walker - Carlsbad CA, US Jing Shi - Carlsbad CA, US Tito A. Serafini - Belmont CA, US
Compositions and methods are provided for prognostic classification of inflammatory diseases, e.g. inflammatory demyelinating disease, patients into subtypes, which subtypes are informative of the patient's need for therapy and responsiveness to a therapy of interest. The patterns of cytokines provides for a signature pattern that can identify patients likely to benefit from therapeutic intervention as well as discriminate patients that have a high probability of responsiveness to a therapy from those that have a low probability of responsiveness. Assessment of this signature pattern thus allows improved methods of care. In one embodiment of the invention, the autoimmune disease is multiple sclerosis or neuromyelitis optica.
Markers For Determination Of Patient Responsiveness
Robert C. Axtell - Menlo Park CA, US Lawrence Steinman - Stanford CA, US May H. Han - Menlo Park CA, US Brigit A. de Jong - Nijmegen, NL Chander Raman - Birmingham AL, US Michael Walker - Carlsbad CA, US Jing Shi - Carlsbad CA, US
Compositions and methods are provided for prognostic classification of inflammatory diseases, e.g. inflammatory demyelinating disease, patients into subtypes, which subtypes are informative of the patient's need for therapy and responsiveness to a therapy of interest. The patterns of cytokines provides for a signature pattern that can identify patients likely to benefit from therapeutic intervention as well as discriminate patients that have a high probability of responsiveness to a therapy from those that have a low probability of responsiveness. Assessment of this signature pattern thus allows improved methods of care. In one embodiment of the invention, the autoimmune disease is multiple sclerosis or neuromyelitis optica.