Charles L Barnett

Address:

8232 Rumford Rd, Indianapolis, IN 46219

VIN:

4T4BE46K98R024586

Make:

TOYOTA

Model:

CAMRY

Year:

2008

US Patent:

6426417, Jul 30, 2002

Filed:

Aug 2, 2000

Appl. No.:

09/601707

Inventors:

Charles Jackson Barnett - Indianapolis IN
Steven Eugene Dunlap - Fishers IN
Michael Edward Kobierski - Greenwood IN
John Arnold Werner - Indianapolis IN

Assignee:

Eli Lilly and Company - Indianapolis IN

International Classification:

C07D47102

US Classification:

544279

US Patent:

6570016, May 27, 2003

Filed:

Nov 14, 2001

Appl. No.:

09/979598

Inventors:

Bret Anthony Astleford - Martinsville IN
Charles Jackson Barnett - Indianapolis IN
Michael Edward Kobierski - Greenwood IN
Thomas Michael Wilson - Speedway IN

Assignee:

Eli Lilly and Company - Indianapolis IN

International Classification:

C07D295073

US Classification:

544381, 544363

Abstract:

This invention provides a process to prepare (2R)-anti-5-{3-[4-(10,11-difluoromethanodibenzosuber-5-yl)piperazin-1-yl]-2-hydroxypropoxy}quinoline.

US Patent:

6624304, Sep 23, 2003

Filed:

Mar 3, 2003

Appl. No.:

10/378436

Inventors:

Bret Anthony Astleford - Martinsville IN
Charles Jackson Barnett - Indianapolis IN
Michael Edward Kobierski - Greenwood IN
Thomas Michael Wilson - Speedway IN

Assignee:

Eli Lilly and Company - Indianapolis IN

International Classification:

C07D295073

US Classification:

544381, 544363

Abstract:

This invention provides a process to prepare (2R)-anti-5-{3-[4-(10,11-difluoromethanodibenzosuber-5-yl)piperazin-1-yl]-2-hydroxypropoxy}quinoline.

US Patent:

20040010005, Jan 15, 2004

Filed:

Feb 21, 2003

Appl. No.:

10/362496

Inventors:

Charles Barnett - Indianapolis IN, US
Rui Gu - Indianapolis IN, US
Michael Kobierski - Greenwood IN, US

International Classification:

C07D491/02
A61K031/4745

US Classification:

514/292000, 546/083000

Abstract:

A process for preparing (1R,3S)-3-(9-chloro-3-methyl-4-oxo-5H-(isoxazoloquinolin-5-yl))cyclohexanecarboxylic acid and esters thereof, as represented by formulas II and III, wherein R is a lower alkyl groups, and A and B are N or O, provided that when A is N, B is O, or when A is O, B is N: Formula (III) and Formula (II).

US Patent:

54162114, May 16, 1995

Filed:

May 24, 1993

Appl. No.:

8/066831

Inventors:

Charles J. Barnett - Indianapolis IN
Thomas M. Wilson - Speedway IN

Assignee:

Eli Lilly and Company - Indianapolis IN

International Classification:

C07D48704
C07B 3710

US Classification:

544280

Abstract:

Processes for preparing 5-substituted pyrrolo[2,3-d]pyrimidines which are useful as intermediates for the preparation of pyrrolo[2,3-d]pyrimidine antineoplastic agents or as antineoplastic agents themselves are provided.

US Patent:

51590905, Oct 27, 1992

Filed:

Apr 16, 1991

Appl. No.:

7/641969

Inventors:

Charles J. Barnett - Indianapolis IN
Thomas M. Wilson - Indianapolis IN

Assignee:

Eli Lilly and Company - Indianapolis IN

International Classification:

C07C24900
C07C 6976
C07C 6702
C07D47102

US Classification:

552 10

Abstract:

A process and intermediates for the enantioselective synthesis of 5,10-dideaza-5,6,7,8-tetrahydrofolic acid are disclosed.

US Patent:

52783073, Jan 11, 1994

Filed:

Sep 25, 1992

Appl. No.:

7/951483

Inventors:

Charles J. Barnett - Indianapolis IN
Thomas M. Wilson - Speedway IN

Assignee:

Eli Lilly and Company - Indianapolis IN

International Classification:

C07B 4102
C07D48704

US Classification:

544280

Abstract:

The present invention provides a process for preparing a 4-hydroxypyrrolo[2,3-d]pyrimidine derivative of the formula ##STR1## wherein R is NHC*H(COOR. sup. 1)CH. sub. 2 CH. sub. 2 COOR. sup. 1 or OR. sup. 1 ; R. sup. 1 is H or a carboxyl protecting group; the configuration about the carbon atom designated * is L; n is 0 or 1; and A is an aryl group optionally having, in addition to the COR substituent, one or two substituents selected from the group consisting of halo, hydroxy, C. sub. 1 -C. sub. 4 alkyl and C. sub. 1 -C. sub. 4 alkoxy; or a salt thereof, which comprises (a) halogenating a compound of the formula ##STR2## wherein R, R. sup. 1, A and * are as defined above; j is 0 or 1; and (b) reacting 2,4-diamino-6-hydroxypyrimidine, or a salt thereof, with the reaction product from step (a), in the presence of a polar solvent.

US Patent:

54866146, Jan 23, 1996

Filed:

May 30, 1995

Appl. No.:

8/453529

Inventors:

Charles J. Barnett - Indianapolis IN
Thomas M. Wilson - Speedway IN

Assignee:

Eli Lilly and Company - Indianapolis IN

International Classification:

C07D21178
C07D40506
C07D40906

US Classification:

546207

Abstract:

This invention relates to intermediates, and processes thereto, for the preparation of tetrahydropyrido[2,3-d]pyrimidines which are useful for the treatment of susceptable neoplasms. The intermediates have the following formula II; ##STR1## wherein the R, R. sup. 1 and A groups are as defined in the specification.